Norepinephrine at Extubation: No Weight-Related Reintubation Risk

This multicenter cohort study investigated the association between the use of norepinephrine at the time of extubation and the rate of reintubation within 7 days in critically ill patients, with a specific focus on those... read more

4D Trial Unlocks Calm: Dexmedetomidine Eases Hyperactive Delirium in Non-Intubated ICU Patients

The 4D randomized clinical trial, a multicenter, double-blind, placebo-controlled study conducted across nine ICUs, investigated the effectiveness of continuous intravenous dexmedetomidine infusion versus placebo in non-intubated... read more

The Airway Manual: Practical Approach to Airway Management

The book provides up-to-date and easy to understand information on airway management with special emphasis on practical management along with required theory background and key points. It covers all aspects of airway management... read more

The Airway Manual: Practical Approach to Airway Management

Mechanical Ventilation in Emergency Medicine

This book discusses mechanical ventilation in emergency settings, covering the management of patients from the time of intubation until transfer to the ICU. It provides an introduction to key concepts of physiology pertinent... read more

Mechanical Ventilation in Emergency Medicine

Managing a Critically Ill Patient with HIV, TB, and COVID-19

Treating a patient with HIV, active tuberculosis (TB), and COVID-19 is an immense clinical challenge due to the complex interplay of these three infections. This rare but dangerous combination significantly increases the... read more

Endotracheal Intubation Preoxygenation in Resource-limited Settings

Optimal preoxygenation strategies for endotracheal intubation (ETI) in LRS require both protocol adaptation and clinical resourcefulness. An individualized approach using the most feasible combination of techniques should... read more

The Influencing Factors of Neonatal Extubation Failure

This study conducted a systematic review and meta-analysis of 22 studies, revealing significant differences in risk factors between the extubation success and failure groups. Subgroup analysis further showed variations in... read more

Airway Management Success in Out-of-hospital Cardiac Arrest Using Different Devices

Although this study found no significant difference in the FPS rates between direct laryngoscopy and video laryngoscopy, the more frequent use of conventional laryngoscopy was associated with a lower FPS rate among anesthetists.... read more

Early Multimodal Rehabilitation Safely Accelerates Recovery for Ventilated Patients

This single-center, controlled clinical trial investigates the efficacy and safety of an early multimodal rehabilitation program (MRP) versus a late MRP in mechanically ventilated adult patients in the intensive care unit... read more

Intubating the Critically Ill Patient: A Step-by-Step Guide for Success in the ED and ICU

Intubating critically ill patients is a process that requires a well-thought-out, step-by-step plan, specific to each patient. This book teaches the steps necessary to predict, prepare, perform, and provide pre and post-intubation... read more

Intubating the Critically Ill Patient: A Step-by-Step Guide for Success in the ED and ICU

Thirst Management in Orotracheally Intubated and Mechanically Ventilated Patients

Symptom Management Theory (SMT)-based thirst management is an effective strategy. The 5 mL cold water spray method significantly reduces thirst intensity and distress in mechanically ventilated patients under fasting and... read more

Analgosedation Practice During Noninvasive Respiratory Supports

Sedation is frequently used in patients with acute respiratory failure (ARF) undergoing Noninvasive Respiratory Supports (NRSs). Current analgesic practices are becoming more standardized, with analgosedation strategies increasingly... read more

Accurate Percutaneous Tracheal Tube Placement Using Visual-Guided Transillumination Method

The novel Illuminated Tracheal Alignment Guide (iTAG) device and technique is the first of our knowledge to test the identification of tracheostomy sites by way of laser-guided transillumination. We believe this device... read more

Extubation in the Operating Room After Elective On-pump CABG Surgery

Although immediate extubation in the operating room following on-pump coronary artery bypass graft (CABG) surgery did not show significant differences in ICU or hospital length of stay (LOS), mortality, or ICU readmission... read more

NIV Effectiveness in Critical Patients with ARF and Do Not Intubate Order

The prevalence of do-not-intubate (DNI) order was frequent in patients with acute respiratory failure (ARF) admitted to the ICU, being related to age, comorbidity, frailty and the underlying disease. non-invasive ventilation... read more

Nebulized Furosemide Effect on the Mortality of Mechanically Ventilated ARDS Adult Patients

This RCT tackles an important topic in critical care medicine, which involves a large number of critically ill patients and continues to harbor high mortality despite improvements in management. The results of the study... read more

Bundle of Care Effectiveness on Tolerance of Awake-prone Positioning in ARF Patients

In the evaluated population of patients with COVID-19-related ARF, implementing a bundle-of-care strategy was associated with a longer AW-PP exposure and a reduced risk of endotracheal intubation. In this secondary analysis... read more

NHF Oxygen During Apnoea on Hypoxemia and Intubation Success in Pediatric Emergency and ICU

The use of nasal high-flow (NHF) during emergency intubation in children did not result in a reduction in hypoxemic events or an increase in the frequency of successful intubation on the first attempt. However, in the... read more

Helmet CPAP as NIV for COVID-19 Patients

The COVID-19 pandemic has challenged healthcare systems globally, highlighting the need for effective respiratory support strategies. Helmet continuous positive airway pressure (CPAP) has emerged as a potential noninvasive... read more

Tracheostomy in COVID-19 Patients

Tracheostomy is common in critically ill COVID-19 patients. In patients predicted to need a tracheostomy at some point, early, rather than late, tracheostomy might be a means to reduce the time spent in ICU. However,... read more

Different Anticoagulation Regimens Effectiveness in Critically Ill Patients

This study compared the efficacy of therapeutic anticoagulation guided by anti-Xa levels vs. a D-dimer-based protocol in ICU patients with COVID-19. Given the heightened risk of thrombosis despite anticoagulation therapy... read more

Exploring the Effectiveness of HFNC in the Neurointensive Care Unit

The high flow nasal cannula (HFNC) is becoming increasingly prevalent in both adult and pediatric general intensive care. Despite limited reporting in neurocritical care, we have successfully utilized HFNC in our cohort... read more