Microbial Dynamics and Pulmonary Immune Responses in COVID-19 Secondary Bacterial Pneumonia

Secondary bacterial pneumonia (2°BP) is associated with significant morbidity following respiratory viral infection, yet remains incompletely understood. In a prospective cohort of 112 critically ill adults intubated... read more

Core Topics in Airway Management

Core Topics in Airway Management

Management of the airway is an important and challenging aspect of many clinicians' work and is a source of complications and litigation. The new edition of this popular book remains a clear, practical and highly-illustrated... read more

A Retrospective Closed Cohort Study on Distribution of Multidrug-Resistant Bacteria in VAP and its Impact on Patient Outcome

Gram-negative organisms, particularly Klebsiella and Acinetobacter, were the main multidrug-resistant (MDR) ventilator-associated pneumonia (VAP) culprits. MDR-VAP exhibited higher morbidity and mortality. A study... read more

Oxygen Therapy and Noninvasive Respiratory Supports in Acute Hypoxemic Respiratory Failure

Whereas oxygen supplementation should be initiated for patients with acute hypoxemic respiratory failure defined as PaO2 below 60 mm Hg or SpO2 ... read more

Sleep Disturbances Impact on Outcomes in ICU

Complete disappearance of rapid eye movement (REM) sleep was frequently observed in ICUs (50% of patients) and may occur at all times during the ICU stay, as well as in patients breathing spontaneously, after admission or... read more

Optimizing Oxygenation For Tracheal Intubation in Critically Ill Patients

Tracheal intubation (TI) is a common procedure frequently performed in critically ill patients and is an integral part of emergency airway management (EAM). However, it carries inherent risks and can significantly impact... read more

Tracheal Intubation in Critically Ill Adults with a Physiologically Difficult Airway

Using a Delphi method, agreement among a panel of international experts was reached for 53 statements providing guidance to clinicians worldwide on safe tracheal intubation practices in patients with a physiologically difficult... read more

Pressure Support Ventilation During ECMO Support in Patients with ARDS

In the initial phases of veno-venous extracorporeal membrane oxygenation (VV ECMO) support for severe acute respiratory distress syndrome (ARDS), ultraprotective controlled mechanical ventilation (CMV) is typically employed... read more

Prehospital Treatment of Severely Burned Patients

In the Berlin metropolitan area, paramedics and emergency physicians caring for severely burned patients need to consider long transport times. Current adherence to prehospital treatment recommendations is unsatisfactory.... read more

The Airway Manual: Practical Approach to Airway Management

The Airway Manual: Practical Approach to Airway Management

The book provides up-to-date and easy to understand information on airway management with special emphasis on practical management along with required theory background and key points. It covers all aspects of airway management... read more

Cardiac Arrest During a Ferric Derisomaltose Infusion Followed by Complete Heart Block

Bradycardia and heart block are rarely reported in the parenteral iron literature. Although rare, it may be reasonable to consider parenteral iron as a toxicological etiology for patients presenting with complete heart block... read more

Impact of extended lung protection during mechanical ventilation on lung recovery in patients with COVID-19 ARDS

The extended lung protection with strict control of ΔP for moderate to severe ARDS plus deranged mechanics is feasible and could be implemented in this pilot study with some beneficial impact on the recovery of lung function.... read more

Cardiac Arrest Following Prone Positioning

The complications that can arise from the prone position are often underestimated. Proceduralists, surgeons, and anesthesiologists need to be thoroughly knowledgeable about the common physiological changes that can occur... read more

Noninvasive Ventilation for Preoxygenation during Emergency Intubation

Among critically ill adults undergoing tracheal intubation, preoxygenation with noninvasive ventilation resulted in a lower incidence of hypoxemia during intubation than preoxygenation with an oxygen mask. Among the 1,301... read more

Risk Factors of Post-intubation Hypotension in Severe Pneumonia Patients

Post-intubation hypotension (PIH) was one of the serious complications after Endotracheal intubation (ETI) in Severe pneumonia (SP) patients. The risk factors of PIH were investigated in SP patients to provide a theoretical... read more

Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol

Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol

This quality improvement (QI) project aimed to standardize and re-establish RT-driven protocol for screening patients for SBT readiness and administering SBTs to appropriate patients. Endotracheally intubated and mechanically... read more

Critical Hypertension in Trauma Patients Following Prehospital Emergency Anesthesia

Critical Hypertension in Trauma Patients Following Prehospital Emergency Anesthesia

Delivery of prehospital emergency anesthesia (PHEA) to seriously injured trauma patients risks hemodynamic fluctuation. In adult trauma patients undergoing PHEA, 11.9% of patients experienced post-PHEA critical hypertension.... read more