Tag: intubation
Emergency Department Hyperoxia Associated with Increased Mortality in Mechanically Ventilated Patients
Emergency Department exposure to hyperoxia is common and associated with increased mortality in mechanically ventilated patients achieving normoxia after admission. This suggests that hyperoxia in the immediate post-intubation... read more
Airway Closure during Surgical Pneumoperitoneum in Obese Patients
In obese patients, complete airway closure is frequent during anesthesia and is worsened by Trendelenburg pneumoperitoneum, which increases airway opening pressure and alveolar pressure: besides preventing alveolar derecruitment,... read more
Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults
Lower respiratory tract infections (LRTIs) are the leading cause of infectious disease-related deaths worldwide yet remain challenging to diagnose because of limitations in existing microbiologic tests. In critically ill... read more
Effect of High-Flow Nasal Oxygen vs Standard Oxygen on 28-Day Mortality in Immunocompromised Patients With ARF
Among critically ill immunocompromised patients with acute respiratory failure (ARF), high-flow oxygen therapy did not significantly decrease day-28 mortality compared with standard oxygen therapy. Of 778 randomized patients... read more
Alternatives to Rapid Sequence Intubation: Contemporary Airway Management with Ketamine
Endotracheal intubation (ETI) is a high-risk procedure commonly performed in emergency medicine, critical care, and the prehospital setting. Traditional rapid sequence intubation (RSI), the simultaneous administration of... read more
Noninvasive ventilation for avoidance of reintubation in patients with various cough strength
The aim of this study was to assess whether prophylactic noninvasive ventilation (NIV) would benefit patients with various cough strengths.... read more
The Effect of Adhesive Tape vs. Endotracheal Tube Fastener in Critically Ill Adults
The optimal securement method of endotracheal tubes is unknown but should prevent dislodgement while minimizing complications. The use of an endotracheal tube fastener might reduce complications among critically ill adults... read more
PERFECT Protocol: Volume-based Feeding in Ventilated Adults
Underfeeding in critical illness is common and associated with poor outcomes. Researchers in the UK designed a before-and-after study to evaluate the safety, efficacy and clinical outcomes associated with volume-based feeding... read more
Tidal Volume Strategies for those without ARDS
This paper justifies utilizing a higher tidal volume strategy for our patients without primary ARDS/pulmonary disease. This can be very useful. Patient comfort and patient-ventilator synchrony are extremely important. This... read more
Diagnosis and Management of Acute Exacerbations of COPD – Pharmacology CME
As more and more patients present to the ED with symptoms that suggest an acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD) –worsening dyspnea, cough and sputum production – emergency clinicians can... read more
Tracheal Intubation Practice and Safety Across International PICUs
There were both similarities and differences in tracheal intubation practice and outcomes across international PICUs. Fewer adverse tracheal intubation–associated events were reported from International versus North American... read more
Airway Management in Microgravity
In the near future, space programs will shift their focus toward long‐duration interplanetary missions, in particular to the Moon and Mars. These exploration missions will be associated with an increased risk of acute medical... read more
Sleep Deprived-Patients in ICU May Fail to Get Off Ventilation
Attempts to wean intubated, critically ill patients off mechanical ventilators were less successful when the patients exhibited atypical sleep or pathological wakefulness, researchers reported. The findings suggest that sleep... read more
Bag-Mask Ventilation during Tracheal Intubation of Critically Ill Adults
Among critically ill adults undergoing tracheal intubation, patients receiving bag-mask ventilation had higher oxygen saturations and a lower incidence of severe hypoxemia than those receiving no ventilation. Among the 401... read more
The PreVent Trial, Assessing the Role of Bag-mask Ventilation During Tracheal Intubation in Critically Ill Adults
In this "Breathe Easy Critical Perspective" podcast, Dr. Dominique Pepper interviews Dr. Matthew Semler. They discuss the PreVent trial, a recent publication in the 2019 issue of the NEJM that assessed the role of bag-mask... read more
Effect of high-flow nasal cannula oxygen therapy in adults with acute hypoxemic respiratory failure
Conflicting recommendations exist on whether high-flow nasal cannula (HFNC) oxygen therapy should be administered to adult patients in critical care with acute hypoxemic respiratory failure. We performed a meta-analysis of... read more
Cricoid Pressure in Airway Management: The IRIS Trial
This large randomized clinical trial performed in patients undergoing anesthesia with RSI failed to demonstrate the non-inferiority of the sham procedure in preventing pulmonary aspiration. Further studies are required in... read more