Liberation from Invasive Mechanical Ventilation with Continued Receipt of Vasopressor Infusions

Weaning protocols for discontinuation of invasive mechanical ventilation often mandate resolution of shock. Whether extubation while receiving vasopressors is associated with harm is uncertain. To examine whether extubation... read more

Liberation from Invasive Mechanical Ventilation with Continued Receipt of Vasopressor Infusions

Treating Hypoxia in Discharged COVID-19 Patients

The ICU technique of placing a hypoxic patient in a prone position is being widely used to care for COVID-19 patients in respiratory distress to improve oxygenation and possibly to avoid intubation. The COVID-19 pandemic... read more

Treating Hypoxia in Discharged COVID-19 Patients

Noninvasive Respiratory Support for COVID-19 Patients: When, for Whom, and How?

The significant mortality rate and prolonged ventilator days associated with invasive mechanical ventilation (IMV) in patients with severe COVID-19 have incited a debate surrounding the use of noninvasive respiratory support... read more

Noninvasive Respiratory Support for COVID-19 Patients: When, for Whom, and How?

Transtracheal Jet Ventilation in the Can’t Intubate Can’t Oxygenate Emergency

Transtracheal jet ventilation (TTJV) is associated with a high risk of device failure and barotrauma in the CICO emergency. Guidelines and recommendations supporting the use of TTJV in CICO should be reconsidered. 44 studies... read more

Transtracheal Jet Ventilation in the Can’t Intubate Can’t Oxygenate Emergency

Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 Pneumonia

The research will be retrospective, and will include a review of medical history of all patients admitted in the COVID-19 ICU of the University hospital Osijek during 2020 and 2021. Associated comorbidity, hospital admission... read more

Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 Pneumonia

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19

An overall good trial that supports the use of high flow oxygen therapy in patients with Severe COVID-19. Randomized controlled trial conducted across three centers in Columbia over 5 months from August 2020 to January... read more

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19

Ventilator Modes Made Easy: An Easy Reference for RRT’s, RN’s, and Medical Residents

Who says understanding ventilator modes has to be hard? This book gives you easy to understand information that every RRT, RN, or Resident always wishes they had. Each mode is described in simple language and answers the... read more

Ventilator Modes Made Easy: An Easy Reference for RRT’s, RN’s, and Medical Residents

Respiratory Drive in Sepsis and Septic Shock Patients: Modulation by High-flow Nasal Cannula

Patients with sepsis and septic shock of extrapulmonary origin present elevated respiratory drive and effort, which can be effectively reduced by high-flow nasal cannula. 25 nonintubated patients with extrapulmonary sepsis... read more

Respiratory Drive in Sepsis and Septic Shock Patients: Modulation by High-flow Nasal Cannula

Mechanical Ventilation Promotes Lung Tumor Spread by Modulation of Cholesterol Cell Content

Mechanical stretch of cancer cells can alter their invasiveness. During mechanical ventilation, lungs may be exposed to an increased amount of stretch, but the consequences on lung tumors have not been explored. To characterize... read more

Mechanical Ventilation Promotes Lung Tumor Spread by Modulation of Cholesterol Cell Content

Safe Tracheal Extubation After General Anesthesia

Tracheal extubation generates less interest than tracheal intubation. Research, guidelines and clinical anecdotes tend to focus on airway management at the beginning of anesthesia, and it is rare for the challenges of extubation... read more

Safe Tracheal Extubation After General Anesthesia

Intubation Practice and Outcomes Among Pediatric Emergency Departments

While tracheal intubation (TI) characteristics vary between pediatric Emergency Departments and ICUs, outcomes are similar. Shock and limited mouth opening were independently associated with adverse TI events in the Emergency... read more

Intubation Practice and Outcomes Among Pediatric Emergency Departments

Etomidate vs. Ketamine for Emergency Endotracheal Intubation

While the primary outcome of Day 7 survival was greater in patients randomized to ketamine, there was no significant difference in survival by Day 28. A prospective, randomized, open-label, parallel assignment, single-center... read more

Etomidate vs. Ketamine for Emergency Endotracheal Intubation

Outcome After Intubation for Septic Shock with Respiratory Distress and Hemodynamic Compromise

Intubation within 24 h of sepsis was not associated with hospital mortality but resulted in fewer 28-day hospital-free days. Although intubation remains a high-risk procedure, we did not identify an increased risk in mortality... read more

Outcome After Intubation for Septic Shock with Respiratory Distress and Hemodynamic Compromise

To Bronch or Not to Bronch – That Is the Question

Percutaneous tracheostomy was safely and effectively performed by an experienced surgical team both with and without bronchoscopic guidance with no difference in the complication rates. This study suggests that the use... read more

To Bronch or Not to Bronch – That Is the Question

First-Pass Orotracheal Intubation: Video Laryngoscopy vs. Direct Laryngoscopy

Among patients in the ICU requiring intubation, video laryngoscopy compared with direct laryngoscopy did not improve first-pass orotracheal intubation rates and was associated with higher rates of severe life-threatening... read more

First-Pass Orotracheal Intubation: Video Laryngoscopy vs. Direct Laryngoscopy

Facemask vs. Helmet – Noninvasive Ventilation

We use Noninvasive ventilation (NIV) to treat various disease processes, such as acute hypercapnic and hypoxemic respiratory failure, post-extubation failure, and neuromuscular diseases. Data supports NIV use in some conditions,... read more

Facemask vs. Helmet – Noninvasive Ventilation

Head Rotation in Anaesthetised Apnoeic Patients Significantly Increases Mask Ventilation Efficiency

Head rotation of 45° in anaesthetised apnoeic adults significantly increases the efficiency of mask ventilation compared with the neutral head position. Head rotation is an effective alternative to improve mask ventilation... read more

Head Rotation in Anaesthetised Apnoeic Patients Significantly Increases Mask Ventilation Efficiency