Tag: mechanical ventilation
Flow-controlled Ventilation Enhances Lung Aeration
Lung-protective ventilation for acute respiratory distress syndrome (ARDS) aims for providing sufficient oxygenation and carbon dioxide clearance, while limiting the harmful effects of mechanical ventilation. This study... read more
Validation of Neuromuscular Blocking Agent Use in ARDS
The use of Neuromuscular Blocking Agents (NMBA) could significantly decrease mortality in moderate-to-severe acute respiratory distress syndrome (ARDS) patients and decrease the incidence of barotrauma during mechanical ventilation.... read more
Imaging Changes of Severe COVID-19 Pneumonia in Advanced Stage
The imaging changes of acute stage from a case of 75-year-old male patient with severe COVID-19 pneumonia combined acute respiratory distress syndrome (ARDS), septic shock, and multiple organ dysfunction syndrome (MODS) who... read more
Harmful Effects of Mechanical Ventilation on Neurocognitive Functions
Whether mechanical ventilation (MV) induces neurotoxicity that can trigger or accelerate chronic cognitive disorders is controversial. The relationship between MV and neurocognitive impairment, that persisted at hospital... read more
New Study on Prehospital Airway Control Trial Underway
Emory University Department of Emergency Medicine and Grady Memorial Hospital will take part in a U.S. Department of Defense-funded clinical trial to compare different ways to help people with traumatic injuries breathe. The... read more
Respiratory Drive in the ARDS: Pathophysiology, Monitoring, and Therapeutic Interventions
Neural respiratory drive, i.e., the activity of respiratory centres controlling breathing, is an overlooked physiologic variable which affects the pathophysiology and the clinical outcome of acute respiratory distress syndrome... read more
It’s Insane to Keep Using Mortality As a Primary Endpoint in Critical Care Trials
Mortality is an important endpoint, so we shouldn't ignore mortality trends entirely. However, the vast majority of these will be spurious. Thus, we should generally not change practice due to them. In the history of critical... read more
Coronavirus (2019-nCoV): Evidence Relevant to Critical Care
The 2019 Coronavirus outbreak was declared a global Public Health Emergency by the World Health Organization (WHO) on 30th January 2020. In order to ensure immediate access to relevant systematic reviews, this Cochrane... read more
Ventilatory Support and Mechanical Properties of the Fibrotic Lung Acting as a “Squishy Ball”
The management of the patient with lung fibrosis in the ICU is a challenge for the intensivist. The lack of studies defining the mechanical ventilation strategy, and the different underlying etiologies, make it difficult... read more
Expiratory Muscle Dysfunction in Critically Ill Patients
The expiratory muscles are the "neglected component" of the respiratory muscle pump. Rather as the heart does not comprise only a left ventricle, but also a right one, the respiratory muscle pump is much more than just the... read more
The ABCDE Bundle Associated with Significant Reductions in Duration of Mechanical Ventilation
The focus on long-term consequences of critical illness has intensified with increasing ICU utilization and survivorship. Post Intensive Care Syndrome (PICS) is increasingly recognized and has profound and long-lasting negative... read more
Clinical Decision Support Systems: Future or Present in ICU?
Clinical decision support systems (CDSS) are today, a reality. More complex, useful systems will be developed in the near future, forging CDSS an essential part of ICU monitoring. However, we need to understand the algorithms... read more
Risk Factors for the Development of ARDS in Mechanically Ventilated Adults in Peru
In this study of mechanically ventilated patients, 31% of study participants had acute respiratory distress syndrome (ARDS) at some point during their ICU stay. Optimal lung-protective ventilation was not used in a majority... read more
Effect of Stress Ulcer Prophylaxis on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation
Among ICU patients requiring mechanical ventilation, a strategy of stress ulcer prophylaxis with use of proton pump inhibitors vs histamine-2 receptor blockers resulted in hospital mortality rates of 18.3% vs 17.5%, respectively,... read more
Compliance With Evidence-Based Processes of Care After Transitions Between Staff Intensivists
No significant impact of transitions of care observed between individual staff physicians on evidence-based processes of care for mechanically ventilated adult patients. However, transitions were associated with a lower likelihood... read more
Ventilator Management: Advanced Concepts In Critical Care
Mechanical ventilation is a broad subject that encompasses many factors that must be considered while providing overall resuscitation. It is not as easy as just entering in a rate and tidal volume and pushing start. Critical... read more
Critical Care Opioids Impact in the 21st Century
Critical Care is impacted by opioids in multiple ways. Not only do they form the backbone of managing pain and sedation in the intensive care unit (ICU), the burgeoning opioid epidemic also feeds into opioid-related ICU admissions.... read more
