Handbook of Corticosteroids

Handbook of Corticosteroids

Corticosteroids are a class of steroid hormones which are mainly produced in the adrenal cortex of the vertebrates but are also synthesized artificially. They ease redness, itching, swelling and allergic reactions. There... read more

The Feasibility of Studying Metabolites in PICU MODS

The Feasibility of Studying Metabolites in PICU MODS

Metabolites are generated from critical biological functions and metabolism. This pediatric study reviewed plasma metabolites in patients suffering from multi-organ dysfunction syndrome (MODS) in the pediatric intensive care... read more

Endogenous Agmatine Metabolism Correlated with the Progression of Sepsis

Endogenous Agmatine Metabolism Correlated with the Progression of Sepsis

Supplemental exogenous agmatine could ameliorate the lipopolysaccharide-induced systemic inflammatory responses and multiple organ injuries through the 2 receptor">imidazoline I2 receptor-ribosomal S6 kinase 2-nuclear factor-κB... read more

Medicating patients during extracorporeal membrane oxygenation

Medicating patients during extracorporeal membrane oxygenation

Extracorporeal membrane oxygenation (ECMO), which can support gas exchange or hemodynamics in patients with severe respiratory or cardiac failure, has demonstrated considerable evolution over the last decade [1], with a steady... read more

The Intensive Care Medicine Research Agenda in Nutrition and Metabolism

The Intensive Care Medicine Research Agenda in Nutrition and Metabolism

Priorities for clinical research in the field of nutritional management of critically ill patients were suggested, with the prospect that different nutritional interventions targeted to the appropriate patient population... read more

Resetting the Circadian Clock Might Boost Metabolic Health

Resetting the Circadian Clock Might Boost Metabolic Health

This Medical News feature discusses the role of circadian clock in regulating metabolism. Over the past 20 years, scientists have assembled a clearer picture of the circadian clocks that keep human physiology tuned to the... read more

The Gut Microbiome and Its Role in Cardiovascular Diseases

The Gut Microbiome and Its Role in Cardiovascular Diseases

The trimethylamine/TMAO pathway likely represents only one of many microbe-dependent pathways that will ultimately be linked to cardiovascular disease pathogenesis, and proven to be an important diagnostic and therapeutic... read more

Hypernatremia (Uggggh!)

Hyponatremia has become a little bit sexy. Not so with sodium that is too high. But I’ve seen a bunch of less than ideal management of hypernatremia, so I figured it is time to put out a podcast about it.... read more