Ratio-based Transfusion and Non-trauma Patients

Researchers at Massachusetts General Hospital (MGH) urge caution in adopting ratio-based transfusion - a practice previously studied only in patients with severe traumatic injuries - in non-trauma patients. Their study published... read more

Ratio-based Transfusion and Non-trauma Patients

Presentations of adult septic patients in the prehospital setting as recorded by emergency medical services

The most common keywords related to septic patients’ symptom presentation were: abnormal/ suspected abnormal temperature (64.1.%), pain (38.4%), acute altered mental status (38.2%), weakness of the legs (35.1%), breathing... read more

Presentations of adult septic patients in the prehospital setting as recorded by emergency medical services

Meta-Analysis of Therapeutic Hypothermia for Traumatic Brain Injury in Adult and Pediatric Patients

Therapeutic hypothermia is a likely beneficial treatment following TBI in adults, improving both neurologic outcomes and decreasing mortality rates. Our work suggests that the optimal management strategy to improve both morbidity... read more

Meta-Analysis of Therapeutic Hypothermia for Traumatic Brain Injury in Adult and Pediatric Patients

National ICU Quality Indicators Revisited

The use of QI at a national level is a suitable method to focus on quality in healthcare. Independently of public access to the results, a local or national ICU network will have a lot to gain from engaging in the process... read more

National ICU Quality Indicators Revisited

Cerebral Microbleeds as Predictors of Mortality

Cerebral microbleeds (CMB) represent a common magnetic resonance imaging marker of cerebral small vessel disease, increasingly recognized as a subclinical marker of stroke and dementia risk. CMB detection may reflect the... read more

Cerebral Microbleeds as Predictors of Mortality

Multifaceted educational intervention shortened time to antibiotic administration in children with sepsis

A multifaceted educational intervention shortened time to antibiotic administration in children with severe sepsis and septic shock: ABISS Edusepsis pediatric study. The Surviving Sepsis Campaign (SSC) recommends the administration... read more

Multifaceted educational intervention shortened time to antibiotic administration in children with sepsis

Stapled versus hand-sewn

Stapled versus hand-sewn: A prospective emergency surgery study. An American Association for the Surgery of Trauma multi-institutional study. Data from the trauma patient population suggests handsewn (HS) anastomoses are... read more

Stapled versus hand-sewn

Quality of Care at Hospitals Identified as Outliers in Publicly Reported Mortality Statistics for Percutaneous Coronary Intervention

Public reporting of percutaneous coronary intervention (PCI) outcomes may create disincentives for physicians to provide care for critically ill patients, particularly at institutions with worse clinical outcomes. Large hospitals... read more

Quality of Care at Hospitals Identified as Outliers in Publicly Reported Mortality Statistics for Percutaneous Coronary Intervention

The status of intensive care medicine research and a future agenda for very old patients in the ICU

The "very old intensive care patients" (abbreviated to VOPs; greater than 80 years old) are probably the fastest expanding subgroup of all intensive care unit (ICU) patients. Up until recently most ICU physicians... read more

The status of intensive care medicine research and a future agenda for very old patients in the ICU

Association of β-Blockers With Functional Outcomes After Acute Myocardial Infarction

This cohort study uses Minimum Data Set and Medicare claims data to assess the association of β-blocker use after acute myocardial infarction with functional decline, mortality, and rehospitalization among long-stay nursing... read more

Association of β-Blockers With Functional Outcomes After Acute Myocardial Infarction

MR-proADM Accuracy Superior for Sepsis Mortality Prediction

The use of novel sepsis biomarkers has increased in recent years. However, their prognostic value with respect to illness severity has not been explored. In this work, we examined the ability of mid-regional proadrenomedullin... read more

MR-proADM Accuracy Superior for Sepsis Mortality Prediction

Clinical practice guideline on diagnosis and treatment of hyponatraemia

Hyponatraemia, defined as a serum sodium concentration <135 mmol/l, is the most common disorder of body fluid and electrolyte balance encountered in clinical practice. It can lead to a wide spectrum of clinical symptoms,... read more

Clinical practice guideline on diagnosis and treatment of hyponatraemia

How survival of cancer patients in critical care has improved in the last 3 decades

Comprehensive care for critically ill patients with cancer is a collaborative effort, and close cooperation between oncology as well as palliative and critical care is essential. Collaborative decision making is a cornerstone... read more

How survival of cancer patients in critical care has improved in the last 3 decades

Interventions to improve antibiotic prescribing practices for hospital inpatients

This review includes 221 studies (58 RCTs, and 163 NRS). Most studies were from North America (96) or Europe (87). The remaining studies were from Asia (19), South America (8), Australia (8), and the East Asia (3). We found... read more

Interventions to improve antibiotic prescribing practices for hospital inpatients

Deaths After PCI: Study Compares Public Reporting Models Both With and Without Cardiogenic Shock

Three distinct models for reporting risk-adjusted mortality rates among hospitals and physicians performing PCI in New York State demonstrate a high degree of agreement, despite variation in how they handle the inclusion... read more

Deaths After PCI: Study Compares Public Reporting Models Both With and Without Cardiogenic Shock

Critical Care Patients Benefit From Restrictive Transfusion Strategy

Although a restrictive transfusion strategy significantly reduces the risk for 30-day all-cause mortality in critical care patients, its benefits are less clear in perioperative patients, according to a meta-analysis by a... read more

Critical Care Patients Benefit From Restrictive Transfusion Strategy

Lower C. difficile mortality with vancomycin than metronidazole

Treating Clostridium difficile infection with vancomycin achieves the same recurrence rates as does treatment with metronidazole, but with a significantly lower 30-day mortality, new research suggests. The 30-day mortality... read more

Lower C. difficile mortality with vancomycin than metronidazole