Tag: OHCA
Sodium Bicarbonate In In-Hospital and Out-of-Hospital Cardiac Arrest
Cardiac arrest is a common cause of death worldwide. Sodium bicarbonate (SB) has commonly been used during cardiopulmonary resuscitation (CPR) to correct metabolic acidosis (MA). However, the existence of evidence about its... read more
Treatment of Refractory Cardiac Arrest by Controlled Reperfusion of the Whole Body
This multicenter, prospective, all-comers observational study has provided preliminary data on a new approach to treat patients with prolonged refractory CA and CCPR by applying an advanced extracorporeal perfusion circuit,... read more
ECPR for Hypothermic Refractory Cardiac Arrests in Temperate Climates
Accidental hypothermia designates an unintentional drop in body temperature below 35 °C. There is a major risk of ventricular fibrillation below 28 °C and cardiac arrest is almost inevitable below 24 °C. In such cases,... read more
ECPR in 2023
Extracorporeal cardiopulmonary resuscitation (ECPR) is invasive and resource intense. Data suggesting a survival benefit in patients after OHCA and ECPR derive from retrospective registries and meta-analyses. In order to... read more
Mild Hypercapnia or Normocapnia after OHCA
In patients with coma who were resuscitated after out-of-hospital cardiac arrest (OHCA), targeted mild hypercapnia did not lead to better neurologic outcomes at 6 months than targeted normocapnia. A total of 1,700 patients... read more
Duration of Device-Based Fever Prevention After Cardiac Arrest
While fever prevention for 72 hours after cardiac arrest has been endorsed by international guidelines since 2005, there is a lack of randomized control trial (RCT) generated data supporting this after the initial 24 hours... read more
Differential Diagnosis and Cause-specific Treatment During OHCA
The cardiopulmonary resuscitation (CPR) guidelines recommend identifying and correcting the underlying reversible causes of out-of-hospital cardiac arrest (OHCA). However, it is uncertain how often these causes can be... read more
Emergency vs. Delayed Catheterization in Survivors of OHCA
In this randomized clinical trial, for patients who experience an out-of-hospital cardiac arrest (OHCA) without ST-segment elevation on ECG, a strategy of emergency CAG was not better than a strategy of delayed CAG with respect... read more
Inhaled Hydrogen Efficacy on Neurological Outcome Following Brain Ischemia During Post-cardiac Arrest Care
Inhaled molecular hydrogen gas (H2) has been shown to improve outcomes in animal models of cardiac arrest (CA). H2 inhalation is safe and feasible in patients after CA. We investigated whether inhaled H2 would improve outcomes... read more
COVID-19 Pandemic Effect on the Incidence and Survival Outcomes of EMS-witnessed OHCA
While other international studies have observed higher incidence and reduced survival in non-EMS-witnessed out-of-hospital cardiac arrest (OHCA) during the COVID-19 pandemic, this study did not identify any significant impacts... read more
IHCA Variation Throughout the Day
We observed higher rates of hospital cardiac arrest (IHCA), and poorer outcomes at night. However, in those admitted to ICU, this variation was absent. This suggests patient factors and processes of care issues contribute... read more
Improving Access to ECMO for OHCA
Mobile teams using transport accessibility frameworks and principles can significantly improve patient access for out-of-hospital cardiac arrest (OHCA) compared to in-hospital extracorporeal cardiopulmonary resuscitation... read more
Expert Consensus on PeRcutaneous Cannulation for ECPR
We present inclusion and exclusion criteria and a comprehensive, detailed, generalizable list of best practices for extracorporeal cardiopulmonary resuscitation (ECPR) initiation following refractory out-of-hospital cardiac... read more
Pulse Oximetry Waveform: A Non-invasive Physiological Predictor for the ROSC During CPR
Pulse oximetry plethysmography (POP) may be a novel and effective method for predicting return of spontaneous circulation (ROSC) during resuscitation, with a prognostic value similar to ETCO2 at early stage. 150 out-of-hospital... read more
Epinephrine vs. Norepinephrine in Cardiac Arrest Patients with Post-resuscitation Shock
Among patients with post-resuscitation shock after out-of-hospital cardiac arrest, use of epinephrine was associated with higher all-cause and cardiovascular-specific mortality, compared with norepinephrine infusion. Until... read more
Effect of Intra-arrest Transport, ECPR, and Treatment on Functional Neurologic Outcome
Among patients with refractory out-of-hospital cardiac arrest, the bundle of early intra-arrest transport, extracorporeal cardiopulmonary resuscitation (ECPR), and invasive assessment and treatment did not significantly improve... read more
Optimal CPR Duration for Favorable Neurological Outcomes After OHCA
A favorable neurological outcome is closely related to patient characteristics and total cardiopulmonary resuscitation (CPR) duration. The total CPR duration consists of pre-hospital and in-hospital durations. To... read more
Change in Out-of-Hospital 12-lead ECG Diagnostic Classification in Patients Resuscitated From OHCA
Change in 12-lead ECG classification from OH to ED setting in patients resuscitated from out-of-hospital cardiac arrest (OHCA) was common (49%). The OH STEMI classification changed to a less ischemic (non-STEMI) ED classification... read more
Et Tu, Calcium?
We know our core medications for ACLS (epinephrine, amiodarone, lidocaine) but what is the role of other medications, like calcium? We know calcium can be used in the non-ACLS setting for hyperkalemia to prevent or treat... read more
Hypothermia vs Normothermia for Out-of-Hospital Cardiac Arrest
Hypothermia was first introduced in 2002 by two studies, Bernard et al and The Hypothermia After Cardiac Arrest (HACA) trial. The latter, although a small trial, showed improved neurologic outcomes at six months when patients... read more
Endotracheal Intubation vs. Supraglottic Procedure in Pediatric OHCA
The findings of this large cohort study suggest that endotracheal intubation (ETI) in pediatric out-of-hospital cardiac arrest (OHCA), although performed by trained physicians, is associated with a worse outcome, regardless... read more
