Feasibility of HEMS Performed Prehospital E-CPR in Pediatric Cardiac Arrests

Feasibility of HEMS Performed Prehospital E-CPR in Pediatric Cardiac Arrests

This case-series shows that a properly trained regular Helicopter Emergency Medical Services (HEMS) crew of only two health care professionals (doctor and flight nurse) can establish Extracorporeal-Cardiopulmonary Resuscitation... read more

Neonatology Questions and Controversies: Neonatal Hemodynamics

Neonatology Questions and Controversies: Neonatal Hemodynamics

Dr. Richard Polin's Neonatology Questions and Controversies series highlights the toughest challenges facing physicians and care providers in clinical practice, offering trustworthy guidance on up-to-date diagnostic and treatment... read more

AKI Defined by Fluid-Corrected Creatinine in Premature Neonates

AKI Defined by Fluid-Corrected Creatinine in Premature Neonates

In this secondary analysis of the multicenter PENUT trial, we describe fluid-corrected acute kidney injury (AKI) and evaluate associations with short-term and long-term outcomes in premature neonates with fluid-corrected... read more

Outcomes and Characteristics of Cardiac Arrest in Children with Pulmonary Hypertension

Outcomes and Characteristics of Cardiac Arrest in Children with Pulmonary Hypertension

In this prospective study of children who received CPR in intensive care units, a pre-existing diagnosis pulmonary hypertension was present in 16% of children but was not associated with statistically significant differences... read more

Multiple Electrolytes Solution vs. Saline as Bolus Fluid for Pediatric Septic Shock Resuscitation

Multiple Electrolytes Solution vs. Saline as Bolus Fluid for Pediatric Septic Shock Resuscitation

Among children presenting with septic shock, fluid resuscitation with MES (balanced crystalloid) as compared with 0.9% saline resulted in a significantly lower incidence of new and/or progressive AKI during the first 7 days... read more

Oxygen Support Needs in Children with RSV vs. COVID-19

Oxygen Support Needs in Children with RSV vs. COVID-19

Children with respiratory syncytial virus (RSV) had a higher risk of pneumonia, bronchiolitis, and a hospital stay of more than 4 days vs children with COVID-19 or influenza. Investigators compared demographic and clinical... read more

Multifaceted Early Mobility Intervention Impact for Critically Ill Children

Multifaceted Early Mobility Intervention Impact for Critically Ill Children

This study will examine whether a multifaceted strategy to optimize early mobility affects the duration of mechanical ventilation, delirium incidence, and functional outcomes in critically ill children. This study will... read more

Heparin-based vs. Bivalirudin-based Anticoagulation in Pediatric ECMO

Heparin-based vs. Bivalirudin-based Anticoagulation in Pediatric ECMO

Bivalirudin may be a safe, cost-effective alternative to heparin in achieving anticoagulation in pediatric extracorporeal membrane oxygenation (ECMO) patients. Prospective multicenter studies and randomized control trials... read more

Sick Children Identification in Acute Care Settings

Sick Children Identification in Acute Care Settings

At the heart of every pediatric consultation is the clinician’s responsibility to determine ‘is this child sick?’ In pediatrics illustrative language communicates a clinical picture of the child before us. When... read more

Heterogeneity in Pediatric ARDS: Challenges and Complexities in Diagnosis and Treatment

Heterogeneity in Pediatric ARDS: Challenges and Complexities in Diagnosis and Treatment

Pediatric intensive care physicians are well-acquainted with the concept of heterogeneity, as the patients, pathologies, and treatments they encounter can vary greatly both within the pediatric intensive care unit and within... read more

Pronation Improves Respiratory Outcomes in Neonates with Respiratory Failure

Pronation Improves Respiratory Outcomes in Neonates with Respiratory Failure

This study found that 6-hour periods of pronation (lying on the stomach) can improve gas exchange and lung function in neonates (newborn infants) with three types of respiratory failure, without causing any negative effects... read more

The developing kidney: Perinatal aspects and relevance throughout life

The developing kidney: Perinatal aspects and relevance throughout life

Human perinatal nephrology is a very diverse field in medicine, shared—among others—between obstetricians, neonatologists and nephrologists. Extremely low birth weight infants, babies with growth restriction, and specific... read more

Surfactant Therapies for Pediatric ARDS

Surfactant Therapies for Pediatric ARDS

We advocate for well-designed preclinical and explanatory clinical studies to investigate the use of surfactant for pediatric (PARDS) and neonatal (NARDS) acute respiratory distress syndrome. Given the accumulating knowledge... read more

Pulmonary Aeration and Posterior Collapse Assessed by Electrical Impedance Tomography in Healthy Children

Pulmonary Aeration and Posterior Collapse Assessed by Electrical Impedance Tomography in Healthy Children

The aim of this study was to evaluate the changes in the lung aeration estimated by electrical impedance tomography as the end-expiratory lung impedance after anesthesia induction in pediatric patients. This was a prospective,... read more

Sepsis-Associated AKI Risks in the PICU

Sepsis-Associated AKI Risks in the PICU

In children with severe sepsis, the degree of hemodynamic support as measured by the VIS and the presence of fluid overload may identify patients at increased risk of developing severe acute kidney injury (AKI). Children... read more

Nasotracheal Intubation on Postoperative Neonates with Congenital Heart Disease

Nasotracheal Intubation on Postoperative Neonates with Congenital Heart Disease

Nasotracheal intubation (NTI) is feasible and safe in neonatal cardiac surgery. System-level engagement with stakeholders is necessary to change clinical practice. NTI facilitates early SLP evaluation and treatment and significantly... read more

Trends in Time to Extubation for Pediatric Postoperative Cardiac Patients

Trends in Time to Extubation for Pediatric Postoperative Cardiac Patients

In this large, multicenter database study, early extubation rates in postoperative cardiac patients did not significantly change between 2009 and 2018. Centers that performed early extubation more frequently did not have... read more