Impact of Early Neuraminidase Inhibitor Treatment on Clinical Outcomes in Patients with Influenza B-related Pneumonia

The aim of this study is to evaluate the impact of early (within 2 days after disease onset) neuraminidase inhibitor (NAI) administration on clinical outcomes in patients with laboratory-confirmed influenza B-related pneumonia... read more

Cancer, CVD Patients More Likely to Contract COVID-19

Patients with cancer and cardiovascular disease may have a potentially higher risk of contracting COVID-19 and a higher likelihood of experiencing adverse outcomes from the disease, according to a paper published March 20... read more

Lung Ultrasonography Features of COVID-19 Pneumonia

As lung abnormalities may develop before clinical manifestations and nucleic acid detection, experts have recommended early chest computerized tomography (CT) for screening suspected patients. The high contagiousness... read more

WHO Declares the Coronavirus Outbreak a Pandemic

The World Health Organization on Wednesday declared the rapidly spreading coronavirus outbreak a pandemic, acknowledging what has seemed clear for some time — the virus will likely spread to all countries on the globe. Director-General... read more

Severe Influenza in Critically Ill Patients

The present review summarizes current knowledge on pathogenesis and clinical manifestations of severe influenza. Immunological dysfunction during viral infection correlates with severity and mortality among ICU patients.... read more

Respiratory Support for Patients with COVID-19 Infection

Coronavirus disease 2019 (COVID-19) has affected more than 50 countries so far this year. Xiaobo Yang and colleagues described in their single-centered, retrospective, observational study that 52 of 710 patients with confirmed... read more

Review of the Current Evidence on COVID-19 in Intensive Care

Join Dr. David Lyness as he discusses the current evidence on COVID-19 in Intensive Care. A coronavirus is one of many viruses that cause diseases in mammals and birds. In humans, coronaviruses cause respiratory tract... read more

Critical Care Crisis and Some Recommendations During the COVID-19 Epidemic in China

The COVID-19 epidemic has placed a huge burden on the Chinese health care system. This crisis has dramatically affected the delivery of critical care due to a lack of resources, lack of prediction models and of course the... read more

Imaging Changes of Severe COVID-19 Pneumonia in Advanced Stage

The imaging changes of acute stage from a case of 75-year-old male patient with severe COVID-19 pneumonia combined acute respiratory distress syndrome (ARDS), septic shock, and multiple organ dysfunction syndrome (MODS) who... read more

Empirical Anti-MRSA Therapy Not Associated with Reduced Mortality for Patients with Pneumonia

This study suggests that empirical anti-MRSA therapy was not associated with reduced mortality for any group of patients hospitalized for pneumonia. These results contribute to a growing body of evidence that questions the... read more

Clinical Characteristics of Patients With 2019 Novel Coronavirus

In this single-center case series of 138 hospitalized patients with confirmed 2019 novel coronavirus (2019-nCoV)–infected pneumonia (NCIP) in Wuhan, China, presumed hospital-related transmission of 2019-nCoV was suspected... read more

Interim Clinical Guidance for Management of Patients with Confirmed Coronavirus Infection

This interim guidance is for clinicians caring for patients with confirmed 2019 novel coronavirus (2019-nCoV) infection. CDC will update this interim guidance as more information becomes available. There are a limited... read more

Conservative vs. Interventional Treatment for Spontaneous Pneumothorax

Although the primary outcome was not statistically robust to conservative assumptions about missing data, the trial provides modest evidence that conservative management of primary spontaneous pneumothorax was noninferior... read more

Wuhan Coronavirus Infections Could Be 30 Times Higher Than Official Total

The number of people infected with a SARS-like form of coronavirus in Wuhan, China could already be more than 30 times higher the the official tally, researchers in Hong Kong have warned. Gabriel Leung, the chair of public... read more

Clinical Features of Patients Infected with Coronavirus in Wuhan, China

A cohort of 41 patients with laboratory-confirmed 2019-nCoV infection. Patients had serious, sometimes fatal, pneumonia and were admitted to the designated hospital in Wuhan, China, by Jan 2, 2020. Clinical presentations... read more

The New Coronavirus: What We Do And Don’t Know

A rapidly evolving health story broke in late December when a novel illness originating in Wuhan, China made the news. Reports of the number of infected people swiftly rose, and isolated cases of this new coronavirus —... read more

A Novel Coronavirus from Patients with Pneumonia in China

4 lower respiratory tract samples, including bronchoalveolar-lavage fluid, were collected from patients with pneumonia of unknown cause who were identified in Wuhan on December 21, 2019, or later and who had been present... read more

Clinical Profile and Predictors of Outcome of Pediatric ARDS in a PICU

Pediatric acute respiratory distress syndrome (ARDS) contributes to a significant burden in the PICU of a developing country and is associated with significantly higher mortality. Infection remains the most common etiology.... read more

Risks and Benefits of Stress Ulcer Prophylaxis for Patients With Severe Sepsis

Since the rate of gastrointestinal bleeding requiring endoscopic hemostasis is not different comparing patients with and without stress ulcer prophylaxis, and the increase in hospital-acquired pneumonia is significant, routine... read more

5-year Study Shows Predominance of Non-Device-Associated Pneumonia

Among more than 160,000 patients admitted to University of North Carolina hospitals during a recent 5-year period, non-device-associated, or ND, pneumonia was implicated in three of every four nosocomial pneumonia cases,... read more

In-line Filtration of Intravenous Infusion May Reduce Organ Dysfunction of Adult Critical Patients

In-line filtration with finer 0.2 and 1.2 μm filters may be associated with less organ dysfunction and less inflammation in critically ill adult patients. Comparing fine filter vs control filter cohort, respiratory... read more

Post-extubation Dysphagia

Despite having the tools and techniques for tracheal intubation for > 4000 years, and performing oral intubation with positive pressure mechanical ventilation for > 50 years, only recently has attention focused on... read more