Wuhan Coronavirus Infections Could Be 30 Times Higher Than Official Total

The number of people infected with a SARS-like form of coronavirus in Wuhan, China could already be more than 30 times higher the the official tally, researchers in Hong Kong have warned. Gabriel Leung, the chair of public... read more

Clinical Features of Patients Infected with Coronavirus in Wuhan, China

Clinical Features of Patients Infected with Coronavirus in Wuhan, China

A cohort of 41 patients with laboratory-confirmed 2019-nCoV infection. Patients had serious, sometimes fatal, pneumonia and were admitted to the designated hospital in Wuhan, China, by Jan 2, 2020. Clinical presentations... read more

The New Coronavirus: What We Do And Don’t Know

The New Coronavirus: What We Do And Don’t Know

A rapidly evolving health story broke in late December when a novel illness originating in Wuhan, China made the news. Reports of the number of infected people swiftly rose, and isolated cases of this new coronavirus —... read more

A Novel Coronavirus from Patients with Pneumonia in China

A Novel Coronavirus from Patients with Pneumonia in China

4 lower respiratory tract samples, including bronchoalveolar-lavage fluid, were collected from patients with pneumonia of unknown cause who were identified in Wuhan on December 21, 2019, or later and who had been present... read more

Clinical Profile and Predictors of Outcome of Pediatric ARDS in a PICU

Clinical Profile and Predictors of Outcome of Pediatric ARDS in a PICU

Pediatric acute respiratory distress syndrome (ARDS) contributes to a significant burden in the PICU of a developing country and is associated with significantly higher mortality. Infection remains the most common etiology.... read more

Risks and Benefits of Stress Ulcer Prophylaxis for Patients With Severe Sepsis

Risks and Benefits of Stress Ulcer Prophylaxis for Patients With Severe Sepsis

Since the rate of gastrointestinal bleeding requiring endoscopic hemostasis is not different comparing patients with and without stress ulcer prophylaxis, and the increase in hospital-acquired pneumonia is significant, routine... read more

5-year Study Shows Predominance of Non-Device-Associated Pneumonia

5-year Study Shows Predominance of Non-Device-Associated Pneumonia

Among more than 160,000 patients admitted to University of North Carolina hospitals during a recent 5-year period, non-device-associated, or ND, pneumonia was implicated in three of every four nosocomial pneumonia cases,... read more

In-line Filtration of Intravenous Infusion May Reduce Organ Dysfunction of Adult Critical Patients

In-line Filtration of Intravenous Infusion May Reduce Organ Dysfunction of Adult Critical Patients

In-line filtration with finer 0.2 and 1.2 μm filters may be associated with less organ dysfunction and less inflammation in critically ill adult patients. Comparing fine filter vs control filter cohort, respiratory... read more

Post-extubation Dysphagia

Post-extubation Dysphagia

Despite having the tools and techniques for tracheal intubation for > 4000 years, and performing oral intubation with positive pressure mechanical ventilation for > 50 years, only recently has attention focused on... read more

Serum Creatinine in the Critically Ill Patient With Sepsis

Serum Creatinine in the Critically Ill Patient With Sepsis

A 73-year-old man underwent esophageal resection for cancer. He had a history of hypertension that was treated with an angiotensin receptor blocker. Preoperative estimated glomerular filtration rate (GFR) was 98 mL/min/1.73... read more

Prophylactic Antibiotics After Cardiac Arrest?

Prophylactic Antibiotics After Cardiac Arrest?

This is a multicenter, double-blind, placebo-controlled trial of patients resuscitated from shockable out-of-hospital cardiac arrest.​ Patients were randomized to placebo versus intravenous amoxicillin-clavulanate for two... read more

How Should We Treat Acinetobacter Pneumonia?

How Should We Treat Acinetobacter Pneumonia?

The optimal treatment for multidrug-resistant A. baumannii pneumonia has not been established. New therapeutic options are urgently needed. Well designed, randomized controlled trials must been conducted to comprehensively... read more

The Effect of Early Mobilization in Critically Ill Patients

The Effect of Early Mobilization in Critically Ill Patients

This study indicated that early mobilization was effective in preventing the occurrence of ICU-AW, shortening the length of ICU and hospital stay, and improving the functional mobility. However, it had no effect on the ICU... read more

XueBiJing Injection vs. Placebo for Critically Ill Patients with Severe Community-Acquired Pneumonia

In critically ill patients with severe community-acquired pneumonia, XueBiJing injection led to a statistically significant improvement in the primary endpoint of the pneumonia severity index as well a significant improvement... read more

Development and Assessment of Objective Surveillance Definitions for Nonventilator Hospital-Acquired Pneumonia

Development and Assessment of Objective Surveillance Definitions for Nonventilator Hospital-Acquired Pneumonia

These findings suggest that objective surveillance for NV-HAP using electronically computable definitions that incorporate common clinical criteria is feasible and generates incidence, mortality, and adjusted ORs for hospital... read more

Impact of a Multifaceted Prevention Program on VAP Including Selective Oropharyngeal Decontamination

Impact of a Multifaceted Prevention Program on VAP Including Selective Oropharyngeal Decontamination

Ventilator-associated pneumonia (VAP) remains a serious complication of mechanical ventilation (MV), and has an incidence between 2 and 16 episodes per 1000 ventilator-days, an attributable mortality of 5–13%, excess ICU... read more

Diagnosis of Nonventilated Hospital-acquired Pneumonia

Diagnosis of Nonventilated Hospital-acquired Pneumonia

Nonventilated hospital-acquired pneumonia (NV-HAP) poses several barriers for diagnosis compared with VAP, and the available knowledge is limited. A call for further research in diagnosis of nonventilated HAP is urgent.... read more