Can Ultrasound Predict Histologic Pattern of Lung Injury in COVID‑19 patient?

Can Ultrasound Predict Histologic Pattern of Lung Injury in COVID‑19 patient?

We have read with great interest the study by de Almeida Monteiro et al. recently published in Intensive Care Medicine, where authors studied the relationship between histopathological data and lung ultrasonographic (LUS)... read more

Endemic COVID-19 Needs Novel, Prognostic Tests to Predict Severity and Progression

Endemic COVID-19 Needs Novel, Prognostic Tests to Predict Severity and Progression

COVID-19 has evolved into a long-term population health problem that requires new types of diagnostics. Diagnostic developers, therefore, are called on to expand their developmental focus to include novel tests to predict... read more

Prophylaxis for Pneumocystis Pneumonia in non‐HIV Immunocompromised Patients

Prophylaxis for Pneumocystis Pneumonia in non‐HIV Immunocompromised Patients

Our review shows that TMP/SMX prophylaxis is highly effective for prevention of Prophylaxis for Pneumocystis Pneumonia (PCP) in patients with hematological malignancies, bone marrow transplantation and solid organ transplantation,... read more

Medical oxygen crisis: a belated COVID-19 response

Medical oxygen crisis: a belated COVID-19 response

More than a year into the pandemic, global health agencies have set up a taskforce to address the vast unmet demand for medical oxygen. The global pandemic response mechanism, the Access to COVID-19 Tools Accelerator (ACT-A),... read more

Efficacy of Serum Angiotensin II Levels in Prognosis of Patients with COVID-19

Efficacy of Serum Angiotensin II Levels in Prognosis of Patients with COVID-19

The serum angiotensin II levels decrease significantly in patients with coronavirus disease 2019, and this decrease is correlated with lung damage. There was no statistical significance between the serum angiotensin II... read more

Point-of-Care Ultrasound (POCUS) and COVID-19

Point-of-Care Ultrasound (POCUS) and COVID-19

COVID-19 is a disease caused by infection with SARS-CoV-2, a virus that affects multiple organ systems with numerous disease manifestations. COVID-19 has a specific tropism for the lower respiratory tract, and the most common... read more

No Significant Difference between Tocilizumab and Placebo in Severe COVID-19 Pneumonia Patients

No Significant Difference between Tocilizumab and Placebo in Severe COVID-19 Pneumonia Patients

In this randomized trial involving hospitalized patients with severe COVID-19 pneumonia, the use of tocilizumab did not result in significantly better clinical status or lower mortality than placebo at 28 days. In this... read more

Interleukin-6 Receptor Antagonists in Critically Ill Patients with COVID-19

Interleukin-6 Receptor Antagonists in Critically Ill Patients with COVID-19

In critically ill patients with COVID-19 receiving organ support in ICUs, treatment with the interleukin-6 receptor antagonists tocilizumab and sarilumab improved outcomes, including survival. Both tocilizumab and sarilumab... read more

Effect of Nurse-Led GDLPT on the Prognosis of Pneumonia in Sepsis Patients in the ICU

Effect of Nurse-Led GDLPT on the Prognosis of Pneumonia in Sepsis Patients in the ICU

Nurse-led goal-directed lung physical therapy (GDLPT) improved the outcomes of pneumonia in sepsis patients, and was particularly associated with shortened mechanical ventilation duration and ICU stay, and reduced ICU mortality... read more

Helmet CPAP to treat hypoxic pneumonia outside the ICU

Helmet CPAP to treat hypoxic pneumonia outside the ICU

Respiratory failure due to COVID-19 pneumonia is associated with high mortality and may overwhelm health care systems, due to the surge of patients requiring advanced respiratory support. Shortage of intensive care unit... read more

SOFA Score Accuracy For Determining Mortality Of Severely Ill Patients With COVID-19 Pneumonia

SOFA Score Accuracy For Determining Mortality Of Severely Ill Patients With COVID-19 Pneumonia

The SOFA score possesses inadequate discriminant accuracy to be used for ventilator triage of COVID-19 patients. A better option is needed that incorporates variables specifically related to mortality in patients with COVID-19... read more

Epidemiology and microbiology of ventilator-associated pneumonia in COVID-19 patients

Epidemiology and microbiology of ventilator-associated pneumonia in COVID-19 patients

The COVID-19 pandemic is responsible for many hospitalizations in intensive care units (ICU), with widespread use of invasive mechanical ventilation (IMV) which exposes patients to the risk of ventilator-associated pneumonia... read more

Study finds genetic clues to pneumonia risk and COVID-19 disparities

Study finds genetic clues to pneumonia risk and COVID-19 disparities

Researchers at Vanderbilt University Medical Center and colleagues have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences. Their findings, published... read more

Human ACE2 peptide-mimics block SARS-CoV-2 pulmonary cells infection

Human ACE2 peptide-mimics block SARS-CoV-2 pulmonary cells infection

The current pandemic originated by SARS-CoV-2 causes an unprecedented health crisis. The medical world has found itself helpless in the face of this virus, having to deal with the absence of specific effective treatment.... read more