Tag: research
Implantation of Impella CP LV Assist Device Under the Guidance of 3D Intracardiac Echocardiography
This translational study in ovine model confirms that three-dimensional intracardiac echocardiography is a feasible option to guide implantation of the Impella CP® for left ventricular mechanical support and should be considered... read more
Blood Thinners May Improve Survival Among Hospitalized COVID-19 Patients
Treating hospitalized COVID-19 patients with anticoagulants--blood thinners that slow down clotting--may improve their chances of survival, researchers from the Mount Sinai COVID Informatics Center report. The study,... read more
50 Studies Every Intensivist Should Know
50 Studies Every Intensivist Should Know presents key studies that have shaped the practice of critical care medicine. Selected using a rigorous methodology, the studies cover topics including: sedation and analgesia, resuscitation,... read more
On the Front Lines in Fight Against COVID-19
As a worldwide pandemic washes over the St. Louis region, the Washington University Medical Campus is eerily quiet. Most visitors, students, staff and research faculty are no longer on campus. Limited patients come to its... read more
Pandemic Science Out of Control
A toxic legacy of poor-quality research, media hype, lax regulatory oversight, and vicious partisanship has come home to roost in the search for effective treatments for COVID-19. The rush to offer unproven treatments... read more
COVID-19 and Critical Care
In this podcast, we talk about the clinical journey of a COVID-19 patient and some insights from the critical care unit. There are some concepts here that we probably don't do full justice to in the time we had, so here are... read more
Comparison of Echocardiographic and Invasive Measures of Volaemia and Cardiac Performance in Critically Ill Patients
Static echocardiographic variables did not reliably reflect the volume state as defined by estimates of mean systemic filling pressure. There was no statistical or clinically robust relationship between static echocardiographic... read more
Yale study finds self-isolation would dramatically reduce ICU bed demand
As soon as Alison Galvani learned of the COVID-19 virus in China and its devastating spread there, she foresaw what might happen to healthcare facilities in the United States. The Yale professor and colleagues at the... read more
BCG Vaccination Might Protect Healthcare Workers Against COVID-19
Australian and European researchers are testing if the Bacille Calmette-Guerin (BCG) vaccine, introduced in the 1920s to fight tuberculosis, will be deployed to combat COVID-19, the respiratory disease caused by the novel... read more
Influenza: The Hundred-Year Hunt to Cure the Deadliest Disease in History
A veteran ER doctor explores the troubling, terrifying, and complex history and present-day research of the flu virus, from the origins of the Great Flu that killed millions, to vexing questions such as: are we prepared for... read more
Pandemic: Tracking Contagions, from Cholera to Ebola and Beyond
Prizewinning science journalist Sonia Shah presents a startling examination of the history of viral infections that have ravaged humanity—and how that knowledge prepares us to stop the next worldwide outbreak. Over the... read more
Safety and Immunogenicity Study of 2019-nCoV Vaccine
Vaccine and Treatment Evaluation Unit (VTEU) at Emory is participating in a clinical trial to test an experimental vaccine for COVID-19. The trial began March 16 at Kaiser Permanente Washington Health Research Institute... read more
UC Davis Researchers Race to Develop Coronavirus Solutions
Clinical pathologists, infectious disease physicians and scientists at the UC Davis Medical Center, School of Medicine, California National Primate Research Center and Center for Immunology and Infectious Diseases are collaborating... read more
How Blood From Coronavirus Survivors Might Save Lives
Hospitals in New York City are gearing up to use the blood of people who have recovered from COVID-19 as a possible antidote for the disease. Researchers hope that the century-old approach of infusing patients with the... read more
The Perfect Predator: A Scientist’s Race to Save Her Husband from a Deadly Superbug: A Memoir
A riveting memoir of one woman's extraordinary effort to save her husband's life-and the discovery of a forgotten cure that has the potential to save millions more. Epidemiologist Steffanie Strathdee and her husband, psychologist... read more
Genome: The Autobiography of a Species in 23 Chapters
The genome's been mapped. But what does it mean? Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost... read more
Miracle Cure: The Creation of Antibiotics and the Birth of Modern Medicine
The epic history of how antibiotics were born, saving millions of lives and creating a vast new industry known as Big Pharma. As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set... read more
Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It
The fascinating, true story of the world's deadliest disease. In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children... read more
The Drug Hunters: The Improbable Quest to Discover New Medicines
The surprising, behind-the-scenes story of how our medicines are discovered, told by a veteran drug hunter. The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity—... read more
Focus on Clinical Trial Interpretation
In a recently published meta-epidemiological study of 604 randomised clinical trials (RCTs) published between 1977 and 2018 from 53 Cochrane systematic reviews in critical care, less than 7% of the RCTs had overall low risk... read more
Decrease Delirium in Older ICU Adults Using Music
Researchers from the Regenstrief Institute and Mayo Clinic are leading the first study to test whether exposure to music can decrease delirium in older adults who are receiving mechanical ventilation in the Intensive Care... read more
Instrumental Activities of Daily Living Related to ARDS Survivors’ Quality of Life
Instrumental Activities of Daily Living (IADL), not body functions & structures measures, are related to ARDS survivors' quality of life and should be included in future studies. Bringing greater consistency to outcomes... read more
