Surviving Critical Illness: What Is Next?

This consensus-based framework for PT after hospital discharge aims to improve long-term outcomes for survivors of critical illness. Physical therapists should seek close collaboration with the multidisciplinary team... read more

Interventions for Preventing Critical Illness Polyneuropathy and Critical Illness Myopathy

There is moderate quality evidence from two large trials that intensive insulin therapy reduces CIP/CIM, and high quality evidence that it reduces duration of mechanical ventilation, ICU stay and 180-day mortality, at the... read more

MODS on Day 1 is a Major Source of Mortality in the PICU

Multiple Organ Dysfunction Syndrome (MODS) present on Day 1 of admission continues to be a major source of morbidity and mortality in the PICU, but risk of poor neurologic outcome may be improved. Further research is... read more

Post-ICU Clinics and Peer Support Groups to Reduce PICS

Kyle B. Enfield, MD, and Kimberley J. Haines, PhD, BHSc, discuss implementing post-ICU clinics and peer support groups following critical illness to help reduce the burden of post-intensive care syndrome (PICS). Dr. Haines... read more

Circulating Gasdermin-D in Critically Ill Patients

This is the first study to demonstrate that the active form of GSDM-D is found exclusively in the circulation of septic critically ill patients raising its potential as an agent of dysregulated immunity in systemic infection.... read more

Palliative Care in the Emergency Department As Seen By Providers and Users

This study provides insights into targets for changes in Italian Emergency Departments. Room for improvement relates to training for healthcare professionals on palliative care, the development of a shared care pathway for... read more

What Should You Know About Evidence-Based Guidelines?

As healthcare professionals we want to provide patients the best possible medical care. Prehospital care, like the rest of medicine, is constantly changing, since the research performed today will shape the medical care we... read more

Intra-Operative Events During Cardiac Surgery are Risk Factors for the Development of Delirium in the ICU

Risk factors for delirium following cardiac surgery are incompletely understood. The aim of this study was to investigate whether intra-operative pathophysiological alterations and therapeutic interventions influence... read more

Improving Outcomes for ICU Survivors

In response to the many challenges faced by ICU survivors today, there has been an increasing need to relieve this burden. Despite that many clinical trials have been implemented to find new strategies, post-intensive care... read more

Collaborative Practice in Critical Care Settings

This practical and evidence-based workbook offers a series of assessment, implementation and evaluation activities for professionals working in critical care contexts. Designed to improve the quality of care delivery,... read more

Collaborative Practice in Critical Care Settings

Occupational Therapy in the ICU

The role of occupational therapists in ICU rehabilitation is not currently well established. Current interventions in the ICU are dominated by physical rehabilitation with a growing role in communication and delirium... read more

Traditional vs. Alternative Metrics to Measure the Impact on Critical Care Medicine

In this analysis of major pulmonary and critical care journals the correlation between traditional publishing metrics and Altmetric Attention Scores (AAS) was fair, with a strong positive correlation between citations and... read more

Critically Ill Patients Show a Differential Contractile Response to Neuromuscular Electrical Stimulation

This retrospective sub-analysis aimed to outline the characteristics of, as well as predictors for, a contractile response to Neuromuscular Electrical Stimulation (NMES), and also potential clinical benefits resulting from... read more

Vitamin D Deficiency in ICU Patients

Vitamin D research has experienced a true hype in all fields of medicine in the last decades. In critical illness, this increased interest has only started 10 years ago. The high prevalence of vitamin D deficiency in... read more

Antipsychotics Not Helpful for Delirium in ICU

Delirium is a confused mental state that includes changes in awareness, thinking, judgment, sleeping patterns, and behavior. It can affect patients of any age but is more common among older adults who experience major illness... read more

Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection

The provision of procalcitonin assay results, along with instructions on their interpretation, to emergency department and hospital-based clinicians did not result in less use of antibiotics than did usual care among patients... read more

Determinants of Citation Impact in Large Clinical Trials in Critical Care

Clinical trials conducted by investigator-led research groups are significantly more frequently cited than industry-led trials in critical care medicine. In addition, costs appear to be substantially lower with investigator-led... read more

Comparison of Diagnostic Accuracy Among Procalcitonin, C-reactive protein, and Interleukin 6 for Blood Culture Positivity in General ICU Patients

Despite various technological advances, it still usually takes at least 24 to 48 h to obtain a blood culture result. The subsequent delays in diagnosis and treatment of infection can negatively impact care in the intensive... read more

More Precise Sepsis Therapy with Distinct Clinical Phenotypes

In this retrospective analysis of data sets from patients with sepsis, 4 clinical phenotypes were identified that correlated with host-response patterns and clinical outcomes, and simulations suggested these phenotypes may... read more

Laryngeal Injury and Upper Airway Symptoms After Oral Endotracheal Intubation With Mechanical Ventilation During Critical Care

Laryngeal injury from intubation is common in the ICU setting. Guidelines for laryngeal assessment and postextubation surveillance do not exist. A systematic approach to more robust investigations could increase knowledge... read more

Department-Based ICU Improves Patient Survival Rates

A new Michigan Medicine study found that implementing a dedicated emergency medicine department-based intensive care unit improved patient survival rates and lowered inpatient intensive care unit (ICU) admissions. In the... read more

Outcome Assessment in Advanced Practice Nursing

As the role of the nurse continues to expand in today's healthcare environment, APRNs and DNPs are more frequently tasked with quantifying, evaluating, and improving their individual care processes, as well as demonstrating... read more

Outcome Assessment in Advanced Practice Nursing