Tag: research
Mapping the Brain’s Genetic Landscape
Scientists have taken a step toward building a computer model of the brain's genome, one that may help clarify the genetic roots of schizophrenia, autism and other disorders. For the past two decades, scientists have been... read more
Vitamin Treatment For Sepsis Is Put To The Test
Dr. Jonathan Sevransky was intrigued when he heard that a well-known physician in Virginia had reported remarkable results from a simple treatment for sepsis. Could the leading cause of death in hospitals really be treated... read more
Antimicrobial Chemical Tied to Antibiotic Resistance Genes in Dust
Most people have heard about antibiotic-resistant germs. But how about antibiotic-resistant dust? A new Northwestern University study has found that an antimicrobial chemical called triclosan is abundant in dust — and linked... read more
Reprint of Recovery Programme for ICU Survivors Has No Effect on Relatives’ Quality of Life
The recovery programme intended for intensive care survivors did not have an effect on the relatives. Future recovery programmes should be targeted to help both patient and family, and future research should be conducted... read more
Seeing the Present Through the Past
As an MD-PhD candidate, now in the second year of a history of medicine PhD, I often reflect on the role of history in the medical school classroom and at the bedside. Medical history is a useful way to understand the roots... read more
Discontinuing 5-ASA Safe Upon Anti-TNF Induction for Ulcerative Colitis
Patients with ulcerative colitis who discontinue 5-aminosalicylate therapy once they begin anti-TNF therapy do not appear at great risk for adverse clinical events, according to research published in Gut. Researchers analyzed... read more
A Bold New Strategy for Stopping the Rise of Superbugs
Scientists have pinpointed a molecule that accelerates the evolution of drug-resistant microbes. Now they're trying to find a way to block it. The British chemist Leslie Orgel reputedly once said that "evolution is cleverer... read more
Implanted Organs That Won’t Be Rejected
Breakthrough development uses a patient's own stomach cells, cutting the risk of an immune response to implanted organs. Israeli researchers report that they have invented the first fully personalized tissue implant, engineered... read more
Is a Golden Age of Resuscitation on the Horizon?
Is emergency medicine on the verge of "the dawn of a new golden age of resuscitation?" That's the bold prediction from CPR innovator Keith Lurie, MD, a professor of internal and emergency medicine at the University of Minnesota,... read more
Lab-grown ‘Mini Brains’ Produce Electrical Patterns That Resemble Those of Premature Babies
'Mini brains' grown in a dish have spontaneously produced human-like brain waves for the first time — and the electrical patterns look similar to those seen in premature babies. The advancement could help scientists to... read more
Effect of Bag-Mask Ventilation vs Endotracheal Intubation During CPR on Neurological Outcome After OHCA
Among patients with out-of-hospital cardiorespiratory arrest (OHCA), the use of BMV compared with ETI failed to demonstrate noninferiority or inferiority for survival with favorable 28-day neurological function, an inconclusive... read more
Exploring the Potential Effectiveness of Combining Optimal Nutrition With Electrical Stimulation to Maintain Muscle Health in Critical Illness
This article explores the potential role of nutrition and EMS in maintaining muscle health in critical illness. Within this article, we will evaluate fundamental concepts of muscle wasting and evaluate the effects of EMS,... read more
Erasing Death: The Science That Is Rewriting the Boundaries Between Life and Death
Dr. Sam Parnia, Director of the AWARE Study (AWAreness during REsuscitation) and one of the world's leading experts on the scientific study of death and near-death experiences (NDE), presents cutting-edge research from the... read more
Nurse intuition may play a role in critical-care outcomes
Nurse intuition doesn't sound scientific, but it could play a key role in critical-care outcomes, according to a small study published in DovePress. The researchers conducted a descriptive phenomenological study, interviewing... read more
Never Underestimate the Simple Things We Do To Our Patients
In this compelling episode, Professor Paul Wischmeyer, shares some of his experiences as a patient in the ICU. Since he was 15 he has endured multiple hospitalizations and ICU stays for his inflammatory bowel disease. This... read more
Effect of Human Recombinant Alkaline Phosphatase on 7-Day Creatinine Clearance in Patients With Sepsis-Associated AKI
In this randomized, double-blind, placebo-controlled, dose-finding adaptive phase 2a/2b trial enrolling 301 adults, the optimal therapeutic dose of recombinant alkaline phosphatase was 1.6 mg/kg. Treatment with this dose... read more
Ron Daniels Responds to Study on Sepsis Mortality Rates
New research presented at this year’s ESICM LIVES conference (the annual meeting of the European Society of Intensive Care Medicine) shows that in rich countries overall, mortality from sepsis has fallen by around a quarter... read more
