Interim Clinical Treatment Considerations for Severe Manifestations of Mpox

Interim Clinical Treatment Considerations for Severe Manifestations of Mpox

The Centers for Disease Control and Prevention (CDC) released a Morbidity and Mortality Weekly Report (MMWR) titled "Interim Clinical Treatment Considerations for Severe Manifestations of Mpox—United States, February 2023."... read more

Trauma Group Publishes Action Plan, Makes Data Available for Secondary Analyses

Trauma Group Publishes Action Plan, Makes Data Available for Secondary Analyses

The American College of Surgeons (ACS) has long advocated for the creation of a US National Trauma System to improve quality of care, decrease inequities, and save lives as one of its top legislative priorities, part of which... read more

Molnupiravir Improves Recovery Time in COVID-19 Patients at High Risk of Severe Outcomes

Molnupiravir Improves Recovery Time in COVID-19 Patients at High Risk of Severe Outcomes

This analysis of a large randomized trial involving people who are at high risk of experiencing severe outcomes from COVID-19 and who had been vaccinated against SARS-CoV-2 infection found that adding molnupiravir to usual... read more

China: Nearly 250 million people might be infected with COVID-19

China: Nearly 250 million people might be infected with COVID-19

According to a leaked government document that has been circulating on social media, it is estimated that up to 248 million people in China may have been infected with COVID-19 since control measures were lifted. This... read more

Bougie vs. Endotracheal Tube with Stylet on Successful Intubation

Bougie vs. Endotracheal Tube with Stylet on Successful Intubation

Among critically ill adults undergoing tracheal intubation, use of a bougie did not significantly increase the incidence of successful intubation on the first attempt compared with use of an endotracheal tube with stylet. Among... read more

Algorithm that Detects Sepsis Cut Deaths by 18%

Algorithm that Detects Sepsis Cut Deaths by 18%

Hospital patients are at risk of a number of life-threatening complications, especially sepsis—a condition that can kill within hours and contributes to one out of three in-hospital deaths in the U.S. Overworked doctors... read more

Subphenotypes of AKI in Adults

Subphenotypes of AKI in Adults

Subphenotyping may help reduce heterogeneity under the umbrella term of acute kidney injury (AKI). Despite challenges remain, the identification of AKI subphenotypes has opened the potential of AKI research focused on better... read more

Myocarditis After COVID‐19 mRNA Vaccination in Australia

Myocarditis After COVID‐19 mRNA Vaccination in Australia

Myocarditis in adolescents and young adults following the administration of coronavirus disease 2019 (COVID‐19) mRNA vaccines has been reported. Vaccination of 12–16‐year‐old adolescents with Comirnaty (tozinameran,... read more

Mental Health Morbidity Among Caregivers

Mental Health Morbidity Among Caregivers

While much of the research on post-ICU mental health morbidity has focused upon the survivors themselves, emerging data shows that caregivers of ICU patients are similarly impacted. The collective sequelae experienced... read more

Public Sepsis Awareness Campaigns Should Be Created Based on Local Data

Public Sepsis Awareness Campaigns Should Be Created Based on Local Data

Although public knowledge of sepsis and its mortality is generally low, some countries have high awareness and knowledge, and as such, any public awareness campaigns should be created based on local data. This will also... read more

Intravenous Tenecteplase vs. Alteplase for Acute Ischemic Stroke

Intravenous Tenecteplase vs. Alteplase for Acute Ischemic Stroke

Between Dec 10, 2019, and Jan 25, 2022, 1,600 patients were enrolled and randomly assigned to tenecteplase (n=816) or alteplase (n=784), of whom 1577 were included in the intention-to-treat (ITT) population (n=806 tenecteplase;... read more

Benchmarking Saliency Methods for Chest X-ray Interpretation

Benchmarking Saliency Methods for Chest X-ray Interpretation

Saliency methods, which "explain" deep neural networks by producing heat maps that highlight the areas of the medical image that influence model prediction, are often presented to clinicians as an aid in diagnostic decision-making.... read more

Medical Nutrition Therapy and Clinical Outcomes in Critically Ill Adults

Medical Nutrition Therapy and Clinical Outcomes in Critically Ill Adults

Calorie intake was mainly provided according to the targets recommended by the active ESPEN guideline, but protein intake was lower. In patients staying in ICU ≥ 5 days, early moderate daily calorie and protein intakes... read more

Hydroxychloroquine Not Associated With Decreased Risk for COVID-19 Hospitalization

Hydroxychloroquine Not Associated With Decreased Risk for COVID-19 Hospitalization

Results of a multicenter, double-blinded, randomized controlled trial found no evidence to support the use of hydroxychloroquine for COVID-19 infection in the outpatient setting. These findings were published in The Lancet... read more

Patients Monitored Using Wearable Monitors Experienced Fewer Unplanned ICU Admissions

Patients Monitored Using Wearable Monitors Experienced Fewer Unplanned ICU Admissions

Implementation of continuous monitoring of patient vital signs using wearable monitoring technology linked wirelessly to hospital systems was associated with a reduction in unplanned ICU admissions and rapid response team... read more

Endovascular Resuscitation and Trauma Management

Endovascular Resuscitation and Trauma Management

This book focuses on endovascular methods for resuscitation and trauma management. Written by highly qualified and clinically active physicians from around the world, it shares information gathered over the past decade,... read more

Standardized Data Collection in Prehospital Critical Care

Standardized Data Collection in Prehospital Critical Care

The medical problems categorized by HEMS personnel can be seen as valid. The greatest challenges remain in the classification of stroke and other neurological emergencies. Patients treated by HEMS personnel are characterized... read more