Effect of Out-of-Hospital Sodium Nitrite on Survival to Hospital Admission After Cardiac Arrest

Effect of Out-of-Hospital Sodium Nitrite on Survival to Hospital Admission After Cardiac Arrest

Among patients with out-of-hospital cardiac arrest, administration of sodium nitrite, compared with placebo, did not significantly improve survival to hospital admission. These findings do not support the use of sodium nitrite... read more

Prediction of Neurological Outcomes in Patients Treated With ECPR

Prediction of Neurological Outcomes in Patients Treated With ECPR

This prognostic study develops and validates a prediction model for neurological outcomes of patients with out-of-hospital cardiac arrest with shockable rhythm treated with extracorporeal cardiopulmonary resuscitation. A... read more

Decrease in CPR Initiation During COVID-19 Outbreak

Decrease in CPR Initiation During COVID-19 Outbreak

During the COVID-19 period, we observed decreased initiation of CPR by bystanders and first aid providers for BLS, and decreased ALS by the MMT, regardless if subjects were infected with SARS-CoV-2 or not. ROSC rates... read more

Microtools to Identify and Resuscitate Microcirculatory Dysfunction in Critically Ill Patients

Microtools to Identify and Resuscitate Microcirculatory Dysfunction in Critically Ill Patients

Despite recent advances in the timely restoration of impairments in the oxygen supply chain to the tissue (Yealy et al. 2014; Peake et al. 2014; Mouncey et al. 2015), circulatory shock remains a major contributor to mortality... read more

The Use of Venous Doppler to Predict Adverse Kidney Events in a General ICU Cohort

The Use of Venous Doppler to Predict Adverse Kidney Events in a General ICU Cohort

This study indicates that portal and hepatic flows may be clinical useful tools to help identify patients at risk for renal injury. It is likely that they are indicative of elevated right atrial pressure causing venous congestion,... read more

Viscoelastic Hemostatic Assay Augmented Protocols for Major Trauma Hemorrhage

Our international randomized trial has evaluated the role of VHAs to individualize care and augment empiric hemostatic resuscitation in the challenging and time-critical environment of trauma care. Empiric haemostatic therapy... read more

TEG for Hypocoagulable Patients with Non-Traumatic Bleeding

TEG for Hypocoagulable Patients with Non-Traumatic Bleeding

Thromboelastogram (TEG) has been extensively studied in trauma and surgical patients, but has not been well studied in nontraumatic bleeding, nor has its use been well evaluated in the emergency department. This study... read more

Limiting Radiation in Trauma Imaging & Trauma Resuscitation

Limiting Radiation in Trauma Imaging & Trauma Resuscitation

Appropriate clinical decision-making in the initial evaluation and management of trauma patients in the emergency department is critical to optimize patient outcomes. This supplement provides evidence-based recommendations... read more

Scvo2 in Sepsis: A Measurement Provided by Respiratory Care Practitioners

Scvo2 in Sepsis: A Measurement Provided by Respiratory Care Practitioners

When treating patients with sepsis, intensive care unit (ICU) and emergency department clinicians have learned that improved outcomes occur when staff members work together as a team. This article outlines the value of central... read more

Critical Care and Hospitalist Medicine Made Ridiculously Simple

Critical Care and Hospitalist Medicine Made Ridiculously Simple

A fundamental and thorough guide to the treatment of hospitalized patients in critical care situations, "Critical Care and Hospitalist Medicine Made Ridiculously Simple" provides both introductory information as well as a... read more

Clinical Experience of Whole-body CT as the Initial Evaluation Tool After ECPR in OHCA Patients

Clinical Experience of Whole-body CT as the Initial Evaluation Tool After ECPR in OHCA Patients

Routine whole-body computed tomography (CT) after extracorporeal cardiopulmonary resuscitation (ECPR) in out-of-hospital cardiac arrest (OHCA) patients appears to have a limited role, as the majority is caused by ACS. However,... read more

Cardiopulmonary Resuscitation in the Emergency Department During COVID-19

Cardiopulmonary Resuscitation in the Emergency Department During COVID-19

Emergency medical services (EMS) is called for a 65-year-old man with a 1-week history of cough, fever, and mild shortness of breath now reporting chest pain. Vitals on scene were HR 110, BP 135/90, SpO2 88% on room air.... read more

Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2

Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2

In this case series of hospitalized children who met criteria for PIMS-TS, there was a wide spectrum of presenting signs and symptoms and disease severity, ranging from fever and inflammation to myocardial injury, shock,... read more

Enteral Fluid Resuscitation? The WHO to the rescue in the ED/ICU?

Enteral Fluid Resuscitation? The WHO to the rescue in the ED/ICU?

Prior to the 1970's, restricting oral intake was a "cornerstone" therapy of diarrheal illness, due to the pervasive belief that the GI tract needed time to heal and recover before resuming normal function. This was felt... read more