Fluid Resuscitation with PPD Attenuates Crush Injury-related AKI and Improves Survival

In-hospital renal replacement therapy (RRT) is widely used for the treatments of acute kidney injury (AKI) in crush injury (CI) victims. This study was designed to investigate whether preventive peritoneal dialysis (PPD)... read more

Fluid Resuscitation with PPD Attenuates Crush Injury-related AKI and Improves Survival

Early Mobilization on CRRT is Safe and May Improve Filter Life

Despite studies demonstrating benefit, patients with femoral vascular catheters placed for continuous renal replacement therapy (CRRT) are frequently restricted from mobilization. No researchers have reported filter pressures... read more

Early Mobilization on CRRT is Safe and May Improve Filter Life

Effects of Baseline Thrombocytopenia and Platelet Decrease Following RRT Initiation in Patients With Severe AKI

Baseline thrombocytopenia and platelet decrease following renal replacement therapy initiation were associated with increased mortality, and baseline thrombocytopenia was associated with decreased rates of renal recovery.... read more

Effects of Baseline Thrombocytopenia and Platelet Decrease Following RRT Initiation in Patients With Severe AKI

Identifying At-Risk Patients for Sub-optimal Beta-lactam Exposure in Critically Ill Patients with Severe Infections

Conventional beta-lactam dosing is flawed in critically ill patients. Useful tools such as the MeroRisk Calculator need to be comprehensively evaluated clinically, and if successful should be added into clinical practice... read more

Identifying At-Risk Patients for Sub-optimal Beta-lactam Exposure in Critically Ill Patients with Severe Infections

Sedation in the ICU – Good Past – Better Future?

The concepts for good sedation include defining the range of sedation, the need for agents with rapid response that can be easily and rapidly varied in restless and confused patients, various modes of ventilation, continuous... read more

Sedation in the ICU – Good Past – Better Future?

A Positive Fluid Balance is an Independent Prognostic Factor in Patients with Sepsis

Intravenous fluid administration is an essential component of sepsis management, but a positive fluid balance has been associated with worse prognosis. We analyzed whether a positive fluid balance and its persistence over... read more

A Positive Fluid Balance is an Independent Prognostic Factor in Patients with Sepsis

Continuous RRT – Understanding Circuit Hemodynamics to Improve Therapy Adequacy

The utilization of continuous renal replacement therapy (CRRT) increases throughout the world. Technological improvements have made its administration easier and safer. However, CRRT remains associated with numerous pitfalls... read more

Continuous RRT – Understanding Circuit Hemodynamics to Improve Therapy Adequacy

Hospital Variation in RRT for Sepsis in the United States

Use of renal replacement therapy (RRT) in sepsis varied widely among nationally sampled hospitals without associated differences in mortality. Improving renal replacement standards for the initiation of therapy for sepsis... read more

Hospital Variation in RRT for Sepsis in the United States

The Great Debate Between Balanced and Unbalanced Crystalloids Continues

This meta-analysis contributes very little to the current discussion mainly because of the heterogeneity of included studies. The use of fluid type in different pathologies isn't really what we need, but rather tailored use... read more

The Great Debate Between Balanced and Unbalanced Crystalloids Continues

Optimizing Continuous RRT in the ICU

The consideration of acute kidney injury, its incidence and its impact on the outcome of patients has grown continuously in recent years, leading to an increase in the use of renal replacement therapy (RRT) techniques. Recent... read more

Optimizing Continuous RRT in the ICU

Long-term survival in patients with septic acute kidney injury is strongly influenced by renal recovery

In patients with sepsis, recovery by hospital discharge is associated with long-term survival similar to patients without AKI. Of the 1742 patients who survived to hospital discharge, stage 2–3 AKI occurred in 262 (15%),... read more

Long-term survival in patients with septic acute kidney injury is strongly influenced by renal recovery

A Pilot Study Evaluating the Effect of Cooler Dialysate Temperature on Hemodynamic Stability During Prolonged Intermittent RRT in AKI

Acute kidney injury (AKI) requiring renal replacement therapy (RRT) is associated with high morbidity and mortality. Complications of renal replacement therapy include hemodynamic instability with ensuing shortened treatments,... read more

A Pilot Study Evaluating the Effect of Cooler Dialysate Temperature on Hemodynamic Stability During Prolonged Intermittent RRT in AKI

CRRT for Sepsis-induced Acute Kidney Injury

Sepsis-induced acute kidney injury (SI-AKI) represents the first cause of AKI in ICUs, and renal replacement therapy (RRT) is frequently applied in advanced AKI stages. The debate between 'rescue' indications for RRT start... read more

CRRT for Sepsis-induced Acute Kidney Injury

A modified Delphi process to identify, rank and prioritize quality indicators for CRRT care in critically ill patients

We developed a prioritized list of 13 QIs for continuous renal replacement therapy (CRRT) care. Future work should focus on developing validated benchmarks for these QIs and implementing them into CRRT programs. We conducted... read more

A modified Delphi process to identify, rank and prioritize quality indicators for CRRT care in critically ill patients

Choice of Catheter Size for Infants in Continuous Renal Replacement Therapy

Small size central vascular catheters display optimal rheologic performances in terms of pressures and flows particularly when the renal replacement therapy (RRT) device is equipped with pumps proportional to central vascular... read more

Choice of Catheter Size for Infants in Continuous Renal Replacement Therapy

Complications of Regional Citrate Anticoagulation: Accumulation or Overload?

Based on recent recommendations, the use of Regional Citrate Anticoagulation (RCA) is likely to increase dramatically throughout the world. RCA protocols should aim to minimize the amount of net citrate load delivered to... read more

Complications of Regional Citrate Anticoagulation: Accumulation or Overload?

Caring for Critically Ill Patients in Humanitarian Settings

Critical care medicine is far from the first medical field to come to mind when humanitarian action is mentioned, yet both critical care and humanitarian action share a fundamental purpose to save the lives and ease the suffering... read more

Caring for Critically Ill Patients in Humanitarian Settings

RRT Board Exam: Dominate the Hemodynamic and ECG Portion of the Respiratory Therapy Board Exam

Our RRT Board exam series helps you study smarter, not harder. Instead of giving you information overload, we focus solely on the most recent NBRC TMC and clinical simulation exam matrix. Start feeling more confident and... read more

RRT Board Exam: Dominate the Hemodynamic and ECG Portion of the Respiratory Therapy Board Exam