Tag: sepsis
Rapid and Accurate Sepsis Identification Using AI
This study demonstrates that by providing streamlined predictions using CBC+DIFF data without requiring extensive clinical parameters, the AI-CDSS can be seamlessly integrated into clinical workflows, enhancing rapid, accurate... read more
Managing Recurrent Septic Shock – Dual Blood Purification with CytoSorb and oXiris
This case report presents a patient with recurrent septic shock who experienced significant clinical improvement after receiving adjunctive treatment with a combination of continuous renal replacement therapy (CRRT) using... read more
Cellular Therapy with Mesenchymal Stromal Cells in Sepsis
Cellular therapy with mesenchymal stromal cells (MSCs) is a promising therapeutic modality in sepsis. Positive effects are mainly associated with frequent infusions and the dose of 1 × 106 cell/kg. Larger scale studies... read more
Association Between Early Ondansetron Use and Sepsis Risk in ICU Patients
In both patients with SOFA 3, early ondansetron use was correlated with a reduced risk of sepsis. Patients with early ondansetron use had lower odds of experiencing sepsis than patients without early ondansetron use, which... read more
Handbook of Sepsis
This recently released practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the ICU. Readers will find information on... read more
Code Sepsis – Early Decompensation and Predictors
Early recognition and management of sepsis within the first hour of a sepsis alert is critical for patient survival, requiring healthcare providers to be trained to identify "red flag" symptoms like rapid breathing (tachypnea)... read more
Predicting Sepsis Outcomes – Efficacy of Early Warning Scores
In resource-limited settings, NEWS proved to be the most effective tool for early risk stratification in sepsis patients. Its adoption could significantly enhance sepsis management and improve outcomes in emergency departments... read more
Handbook of Evidence-Based Critical Care
This updated and revised edition of the classic bedside pocket reference remains the gold standard in critical care medicine. The new edition maintains Dr. Marik's trademark humor and engaging writing style, while adding... read more
Using Critical Ultrasound To Predict Early Diagnosis of ICU-acquired Weakness in Septic Patients
This study uncovered pivotal indicators for predicting the occurrence of ICUAW in septic patients. Despite no significant difference in age, gender, BMI, BSA, or SOFA scores between the two groups, the significant differences... read more
Prolonged vs. Intermittent Infusion of Meropenem For Patients with Severe Infection
Prolonged infusion of meropenem is more effective than intermittent infusion in reducing mortality, improving clinical outcomes, and enhancing microbial eradication, without increasing adverse events. These benefits are... read more
Developing a Rapid Screening Tool for High-risk ICU Sepsis Patients
This study demonstrates that machine learning-based prediction models for sepsis can enhance clinical outcomes through accurate risk assessment during the critical first 24h of ICU admission. Despite healthcare system... read more
Severe Sepsis-associated AKI and Outcomes
These results demonstrate an association between an index episode involving SA-AKI and the composite outcome in a defined population. Identification of this group may allow intensive nephrology follow-up and secondary... read more
High cDPP3 Predicts Mortality and Need for Organ Support in Cardiogenic Shock
The present study confirms that circulating dipeptidyl peptidase 3 (cDPP3) and its kinetics are associated with 30-day mortality and the need for organ support in a large and diverse population of CS. The prognostic value... read more
Intubating the Critically Ill Patient: A Step-by-Step Guide for Success in the ED and ICU
Intubating critically ill patients is a process that requires a well-thought-out, step-by-step plan, specific to each patient. This book teaches the steps necessary to predict, prepare, perform, and provide pre and post-intubation... read more
Prediction of AKI in ICU Patients Based on Interpretable Machine Learning
The machine learning model described in this study is capable of accurately predicting the onset of AKI in ICU patients up to 24 hours in advance. Validated within the MIMIC-IV and MIMIC-III databases, the model demonstrates... read more
Intubate Patients with Sepsis Before Midnight or When the Time Comes?
The ever-recurring decision for every clinician is to act or not to act and when to act. The balance of benefit or harm of an intervention and the optimal timing of treatment is not always clear. Intervening or not and... read more
Heparin-binding Protein Predicts Bacterial Infection in Severe Polytrauma Patients
In patients with severe polytrauma, heparin-binding protein may predict bacterial infection. Combining heparin-binding protein, PCT, and neutrophils may improve bacterial infection prediction. HBP provides a referenceable... read more
7-day Fluid Balance Associated with Poor Outcomes
The net fluid balance in patients with sepsis 7 days following ICU administration was significantly related to mortality during hospitalization. Specifically, a 7-day fluid balance > 5,240 mL was associated with poor... read more
Establishment and Validation of a Risk Prediction Model for Sepsis-Associated Liver Injury in ICU Patients
This novel nomogram effectively predicts SALI risk in sepsis patients by integrating readily available clinical parameters. While external validation is needed, the model shows promise as a practical tool for early risk stratification,... read more
