Effect of Standardized Handoff Curriculum on Improved Clinician Preparedness in the ICU

The UW-IPASS standardized handoff curriculum was perceived to improve intensive care provider preparedness and workflow. IPASS-based curricula represent an important step forward in communication standardization efforts and... read more

Effect of Standardized Handoff Curriculum on Improved Clinician Preparedness in the ICU

Development of Dementia in Patients with Femoral Neck Fracture Who Experience Postoperative Delirium

It remains unclear to what extent postoperative delirium (POD) affects the incidence of dementia in hip fracture patients, and the methods used to detect delirium and dementia require validation. The aim of this study was... read more

Development of Dementia in Patients with Femoral Neck Fracture Who Experience Postoperative Delirium

Potentially Modifiable Risk Factors for Long-Term Cognitive Impairment After Critical Illness

Long-term cognitive impairment is common in survivors of critical illness. Little is known about the etiology of this serious complication. We sought to summarize current scientific knowledge about potentially modifiable... read more

Potentially Modifiable Risk Factors for Long-Term Cognitive Impairment After Critical Illness

TAC on Computed Tomography and the Risk of COPD Progression

Total Airway Count (TAC) may reflect the airway-related disease changes that accumulate in the “quiet” zone in early/mild Chronic Obstructive Pulmonary Disease (COPD), indicating that TAC acquired with commercially available... read more

TAC on Computed Tomography and the Risk of COPD Progression

Antimicrobials for the Treatment of Drug-Resistant Acinetobacter Baumannii Pneumonia in Critically Ill Patients

This Bayesian network meta-analysis demonstrated the comparative effectiveness of fifteen antimicrobial treatments for drug-resistant A. baumannii pneumonia in critically ill patients. For survival benefit, SUL appears to... read more

Antimicrobials for the Treatment of Drug-Resistant Acinetobacter Baumannii Pneumonia in Critically Ill Patients

Urine Test Developed to Test for Tuberculosis

An international team of researchers has developed a urine test that can be used to detect tuberculosis (TB) in human patients. Alessandra Luchini and her team have developed a urine test for TB that gives results in 12 hours.... read more

Urine Test Developed to Test for Tuberculosis

Early Identification of Acute Respiratory Distress Disorder in the Absence of Positive Pressure Ventilation

Almost all patients with pulmonary bilateral infiltrates and a PaO2/FIO2 less than or equal to 300 mm Hg under standard oxygen fulfilled the acute respiratory distress syndrome criteria under noninvasive ventilation within... read more

Early Identification of Acute Respiratory Distress Disorder in the Absence of Positive Pressure Ventilation

A Comparison of the qSOFA and SIRS Criteria for the Diagnosis of Sepsis and Prediction of Mortality

Several studies were published to validate quick-SOFA (qSOFA), namely in comparison with Systemic Inflammatory Response Syndrome (SIRS) criteria. We performed a systematic review and a meta-analysis with the aim of comparing... read more

A Comparison of the qSOFA and SIRS Criteria for the Diagnosis of Sepsis and Prediction of Mortality

Effect of Lung Recruitment and Titrated PEEP vs Low PEEP on Mortality in Patients with ARDS

In patients with moderate to severe Acute Respiratory Distress Syndrome (ARDS), a strategy with lung recruitment and titrated Positive End-Expiratory Pressure (PEEP) compared with low PEEP increased 28-day all-cause mortality.... read more

Effect of Lung Recruitment and Titrated PEEP vs Low PEEP on Mortality in Patients with ARDS

The role of serum amyloid A staining of granulomatous tissues for the diagnosis of sarcoidosis

Previous studies demonstrated that SAA staining of sarcoidosis granulomas was qualitatively and quantitatively different from other granulomatous diseases. These data suggest that positive SAA staining of granulomatous tissue... read more

The role of serum amyloid A staining of granulomatous tissues for the diagnosis of sarcoidosis

Sodium Lactate Improves Hemodynamics

Sodium lactate has been shown to improve hemodynamics and avoid fluid overload. The objective of this study was to confirm a beneficial effect on fluid balance with sodium lactate infusion and to specify whether the advantage... read more

Sodium Lactate Improves Hemodynamics

Patient Experiences of Trauma Resuscitation

In this qualitative study that included semistructured interviews and video observations of trauma resuscitation, patients drew satisfaction from trauma team members' demeanor, expertise, and efficiency and valued clear... read more

Patient Experiences of Trauma Resuscitation

Trends and Patterns of Antibiotic Consumption in China

The consumption of antibiotics is a major driver in the development of antimicrobial resistance. This study aims to identify the trends and patterns of the total antibiotic consumption in China’s tertiary hospitals from... read more

Trends and Patterns of Antibiotic Consumption in China

Should Transfusion Trigger Thresholds Differ for Critical Care vs Perioperative Patients?

The safety of restrictive transfusion strategies likely differs for critically ill patients versus perioperative patients. Further trials investigating transfusion strategies in the perioperative setting are necessary. The... read more

Should Transfusion Trigger Thresholds Differ for Critical Care vs Perioperative Patients?

Effect of Boarding on Mortality in ICUs

Mortality increased with boarding of critically ill patients. Further research is needed to identify safer practices for managing patients during periods of high ICU occupancy. The study population consisted of 8,429 patients... read more

Effect of Boarding on Mortality in ICUs

Balanced Crystalloids vs Saline for Critically Ill Adults

Among critically ill adults, use of balanced crystalloids for intravenous fluid administration reduced the composite of death, new renal replacement therapy, and persistent renal dysfunction compared with use of saline. Patients... read more

Balanced Crystalloids vs Saline for Critically Ill Adults

Cisatracurium Ups Some ARDS Outcomes Versus Vecuronium

Among patients with acute respiratory distress syndrome (ARDS), cisatracurium does not improve mortality versus vecuronium but is associated with improvements in other outcomes, according to a study published online in the... read more

Cisatracurium Ups Some ARDS Outcomes Versus Vecuronium

Pilot Feasibility Study of Therapeutic Hypothermia for Moderate to Severe ARDS

Neuromuscular blockade alone does not cause hypothermia but allowed acute respiratory distress syndrome patients to be effectively cooled. Results support conducting a randomized clinical trial of hypothermia in acute respiratory... read more

Pilot Feasibility Study of Therapeutic Hypothermia for Moderate to Severe ARDS