Use of Wearable Devices for Post-discharge Monitoring of ICU patients

Wearable devices generate signals detecting activity, sleep, and heart rate, all of which could enable detailed and near-continuous characterization of recovery following critical illness. We found that wearable devices could... read more

Use of Wearable Devices for Post-discharge Monitoring of ICU patients

iSepsis – A 30ml/kg Bolus: Yes or No -The Results

The results of both surveys are not surprising. This recommendation has never been prospectively tested in a large RCT and has little supporting evidence. Imagine the American Heart Association (AHA) or the American Diabetes... read more

iSepsis – A 30ml/kg Bolus: Yes or No -The Results

Spotlight Interview: The World of Fluids

Looking at the data from a new perspective, the article "Both Positive and Negative Fluid Balance May Be Associated With Reduced Long-Term Survival in the Critically Ill" published in Critical Care Medicine in August 2017,... read more

Spotlight Interview: The World of Fluids

Multicenter Assessment of Sedation and Delirium Practices in the ICU in Poland

A majority of Polish ICUs do not adhere to international guidelines regarding sedation and delirium practices. There continues to be inadequate use of sedation and delirium monitoring tools. High usage of benzodiazepines... read more

Multicenter Assessment of Sedation and Delirium Practices in the ICU in Poland

Lowering systolic blood pressure would save more than 100,000 lives per year, study finds

Intensive treatment to lower systolic (top number) blood pressure to below 120 would save more than 100,000 lives per year in the United States, say scientists. Two thirds of the lives saved would be men and two thirds would... read more

Lowering systolic blood pressure would save more than 100,000 lives per year, study finds

ICU Diary Impact on Patients and Families Wellbeing

The ICU-Diary study: prospective, multicenter comparative study of the impact of an ICU diary on the wellbeing of patients and families in French ICUs. This study will provide new insights on the impact of ICU diaries on... read more

ICU Diary Impact on Patients and Families Wellbeing

Association of the Hospital Readmissions Reduction Program Implementation With Readmission and Mortality Outcomes in Heart Failure

Among fee-for-service Medicare beneficiaries discharged after heart failure hospitalizations, implementation of the HRRP was temporally associated with a reduction in 30-day and 1-year readmissions but an increase in 30-day... read more

Association of the Hospital Readmissions Reduction Program Implementation With Readmission and Mortality Outcomes in Heart Failure

The YEARS Study – Simplified Diagnostic Management of PE

The clinical diagnosis of pulmonary embolism (PE) can be challenging given its variable presentation, requiring dependence on objective testing. Decision instruments such as PERC and the Wells' score help stratify patients... read more

The YEARS Study – Simplified Diagnostic Management of PE

Definitive Global Transfusion Study Supports Patient Safety and Outcomes

Lower thresholds for blood transfusions during cardiac surgery have proven to be safe and provide good patient outcomes compared to traditional thresholds, according to the largest research study ever performed in this area.... read more

Definitive Global Transfusion Study Supports Patient Safety and Outcomes

Sepsis mortality linked to concentration of critical care fellowships

Higher survival rates for sepsis were more concentrated in the Northeast and metropolitan areas in the Western regions of the United States. Compared with other parts of the United States, survival rates for sepsis were highest... read more

Sepsis mortality linked to concentration of critical care fellowships

Enhancing Delirium Case Definitions in Electronic Health Records

Delirium is an acute confusional state, associated with morbidity and mortality in diverse medically ill populations. Delirium may be better captured by composite outcomes, including both administrative claims data and elements... read more

Enhancing Delirium Case Definitions in Electronic Health Records

Is Intravenous Administration of Iodixanol Associated with Increased Risk of AKI, Dialysis, or Mortality?

Among patients at the highest perceived risk of post-contrast Acute Kidney Injury (AKI), intravenous administration of iodixanol for contrast material enhanced CT was not an independent risk factor for AKI, dialysis, or... read more

Is Intravenous Administration of Iodixanol Associated with Increased Risk of AKI, Dialysis, or Mortality?

Hospital Factors May Influence NIV Outcomes Even in Low-Evidence Use

Strong evidence supports use of noninvasive ventilation (NIV) for patients with respiratory distress from chronic obstructive pulmonary disease and heart failure – i.e., strong evidence conditions (SECs). A new study of... read more

Hospital Factors May Influence NIV Outcomes Even in Low-Evidence Use

High Flow Nasal Cannula Use Outside of the ICU – Factors Associated with Failure

High FiO2 requirements, history of intubation, and cardiac co-morbidity are associative predictors of HFNC failure. Bronchiolitis patients may be treated with HFNC outside of the ICU with lower odds of failure. Two hundred... read more

High Flow Nasal Cannula Use Outside of the ICU – Factors Associated with Failure

Review of Strategies to Reduce CLABSI and CAUTI in Adult ICUs

Central line–associated bloodstream infection (CLABSI) and catheter-associated urinary tract infection (CAUTI) are costly and morbid. Despite evidence-based guidelines, Some intensive care units (ICUs) continue to have... read more

Review of Strategies to Reduce CLABSI and CAUTI in Adult ICUs

Perspectives of Survivors, Families and Researchers on Key Outcomes for Research in ARF

There is heterogeneity among the outcomes evaluated in studies of survivors of acute respiratory failure (ARF). Patient, family and researcher groups supported inclusion of outcome domains that fit within the PICS framework.... read more

Perspectives of Survivors, Families and Researchers on Key Outcomes for Research in ARF

Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe hemorrhage

Antifibrinolytics reduce death from bleeding in trauma and post-partum haemorrhage. We examined the effect of treatment delay on the effectiveness of antifibrinolytics. We obtained data for 40,138 patients from two randomised... read more

Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe hemorrhage