GERD Treatment May Reduce Healthcare Visits for Acute Respiratory Infections

GERD Treatment May Reduce Healthcare Visits for Acute Respiratory Infections

Treatment with proton pump inhibitors (PPIs) may help decrease healthcare visits for acute respiratory infections (ARIs) in patients with gastroesophageal reflux disease (GERD). These are the findings of a new study published... read more

Pain Assessment in INTensive care (PAINT)

Pain Assessment in INTensive care (PAINT)

Pain is a common and distressing symptom experienced by intensive care patients. Assessing pain in this environment is challenging, and published guidelines have been inconsistently implemented. The Pain Assessment in INTensive... read more

Major publications in the critical care pharmacotherapy literature

Major publications in the critical care pharmacotherapy literature

The Critical Care Pharmacotherapy Literature Update (CCPLU) Group is composed of over 50 experienced critical care pharmacists who evaluate 31 peer-reviewed journals monthly to identify literature pertaining to pharmacotherapy... read more

Transfusion in Critical Care – UK Regional Audit of Current Practice

Transfusion in Critical Care – UK Regional Audit of Current Practice

A consistent message within critical care publications has been that a restrictive transfusion strategy is non-inferior, and possibly superior, to a liberal strategy for stable, non-bleeding critically ill patients. Translation... read more

Association of β-Blockers With Functional Outcomes After Acute Myocardial Infarction

Association of β-Blockers With Functional Outcomes After Acute Myocardial Infarction

This cohort study uses Minimum Data Set and Medicare claims data to assess the association of β-blocker use after acute myocardial infarction with functional decline, mortality, and rehospitalization among long-stay nursing... read more

Contrast-Induced Nephropathy: Confounding Causation

Contrast-Induced Nephropathy: Confounding Causation

Comparing the methodological rigor of more recent CIN studies to those in the past, it seems clear that earlier studies purporting a causal relationship between AKI and contrast administration were only identifying an association... read more

High Levels of Nosocomial Infection Found in Pediatric ICUs

High Levels of Nosocomial Infection Found in Pediatric ICUs

One in six children in pediatric intensive care units (pICU), and one in ten babies in neonatal intensive care units (nICU) develop a hospital-acquired infection (HAI), according to a new study. Researchers at the European... read more

Delirium: Thinking Clearly About a Foggy Issue

Delirium: Thinking Clearly About a Foggy Issue

Benzodiazepines are one of the leading causes of delirium. These drugs are already falling out of favor in critical care settings for other reasons; they are not easily titratable, and research suggests they can prolong a... read more

Assessing Postoperative Pulmonary Complications After Noncardiothoracic Surgery

Assessing Postoperative Pulmonary Complications After Noncardiothoracic Surgery

In this multicenter study in 1202 American Society of Anesthesiologists physical status 3 patients undergoing noncardiothoracic surgery requiring 2 hours or more of general anesthesia with mechanical ventilation, at least... read more

Rude Surgeons Likely to Make Mistakes

Rude Surgeons Likely to Make Mistakes

A new study finds surgeons with a history of patient complaints about their personalities or attitude are more likely to make mistakes in the operating room. Researchers compared surgical outcomes with patient reports of... read more

Wide variations found in evaluation of newborns for sepsis

Wide variations found in evaluation of newborns for sepsis

The evaluation of well-appearing term infants for early-onset sepsis (EOS) varies considerably among hospitals, with some doing extensive work-ups and giving antibiotics while others simply observe and provide newborn routine... read more

MR-proADM Accuracy Superior for Sepsis Mortality Prediction

MR-proADM Accuracy Superior for Sepsis Mortality Prediction

The use of novel sepsis biomarkers has increased in recent years. However, their prognostic value with respect to illness severity has not been explored. In this work, we examined the ability of mid-regional proadrenomedullin... read more

Carotid Stenting Technology Has More Appeal

Carotid Stenting Technology Has More Appeal

Ten-year follow-up from the CREST trial and 5-year follow-up from the ACT I study, presented at least year's International Stroke Conference, showed that carotid artery stenting (CAS) holds up well over the long term... read more

Sepsis Readmissions Compared With Other Medical Conditions

Sepsis Readmissions Compared With Other Medical Conditions

This study uses data from a US readmissions database to assess whether sepsis hospitalizations account for a higher proportion of unplanned 30-day readmissions than hospitalizations for acute myocardial infarction, heart... read more

Sodium Bicarbonate Versus Sodium Chloride for Preventing Contrast-Associated AKI

Sodium Bicarbonate Versus Sodium Chloride for Preventing Contrast-Associated AKI

Except for urinary pH, none of the outcomes differed between the two groups. Among ICU patients with stable renal function, the benefit of using sodium bicarbonate rather than isotonic sodium chloride for preventing contrast-associated... read more

Interventions to improve antibiotic prescribing practices for hospital inpatients

Interventions to improve antibiotic prescribing practices for hospital inpatients

This review includes 221 studies (58 RCTs, and 163 NRS). Most studies were from North America (96) or Europe (87). The remaining studies were from Asia (19), South America (8), Australia (8), and the East Asia (3). We found... read more

Deaths After PCI: Study Compares Public Reporting Models Both With and Without Cardiogenic Shock

Deaths After PCI: Study Compares Public Reporting Models Both With and Without Cardiogenic Shock

Three distinct models for reporting risk-adjusted mortality rates among hospitals and physicians performing PCI in New York State demonstrate a high degree of agreement, despite variation in how they handle the inclusion... read more