New Study on Molecular Mechanisms Involved in RILF

New Study on Molecular Mechanisms Involved in RILF

Reversible infantile liver failure (RILF) is a heritable mitochondrial condition that causes severe liver dysfunction in infancy, but those who survive the acute stage typically recover and have no further problems. In work... read more

The CAPCRI study on Semi-recumbent positioning

The CAPCRI study on Semi-recumbent positioning

The CAPCRI study(3) conducted by Mireia Llaurado and her team had three aims: to evaluate real semi-recumbent position compliance and degree of head-of-bed elevation in Spanish intensive care units, to describe the relationship... read more

Induced hypothermia not associated with better outcomes for status epilepticus

Induced hypothermia not associated with better outcomes for status epilepticus

In this trial, induced hypothermia added to standard care was not associated with significantly better 90-day outcomes than standard care alone in patients with convulsive status epilepticus.... read more

Serum biomarker associated with metformin dosing or use

Serum biomarker associated with metformin dosing or use

The growth differentiation factor 15 (GDF15) is a novel biomarker for the use and dosing of metformin, according to a study published online Dec. 14 in Diabetes Care. 237 serum biomarkers from participants in the Outcome... read more

Study shows Tumor cells move differently than normal cells

Study shows Tumor cells move differently than normal cells

Drexel University researchers have found that some tumor cells are unable to move like healthy cells, which could impact the way cancer is spread and treated. The team found that certain tumor cells called fibrosarcoma cannot... read more

Outsourced Hospital Cleaning linked to MRSA

Outsourced Hospital Cleaning linked to MRSA

Analysis of English NHS hospitals suggests that employing private as opposed to in-house cleaners is a false economy. While it may reduce costs, it could also raise risk of infection by methicillin-resistant Staphylococcus... read more

Different Rest Intervals in Low-load Resistance Training

Different Rest Intervals in Low-load Resistance Training

Acute hormonal responses, as well as chronic changes in muscle hypertrophy and strength in low-load training to failure are independent of the rest interval length.... read more

How nurses support families of ICU patients towards the end of life

How nurses support families of ICU patients towards the end of life

Researchers gathered evidence on how nurses care for patients and their families in intensive care when life-sustaining treatment is withdrawn. The included studies explored the care of the family before, during and after... read more

Here is Why COPD Disrupts Lung-Repair Ability

Here is Why COPD Disrupts Lung-Repair Ability

In chronic obstructive pulmonary disease (COPD), the patients' lungs lose their ability to repair damage on their own. Scientists at the Helmholtz Zentrum München, partner in the German Center for Lung Research, now... read more

Reducing Natalizumab Concentration May Reduce PML Risk

Reducing Natalizumab Concentration May Reduce PML Risk

Serum concentrations of natalizumab do not appear to rise before patients with relapsing-remitting multiple sclerosis are diagnosed with progressive multifocal leukoencephalopathy, contradicting the hypothesis that exposure... read more

Effectiveness of Pre-Hospital Blood Products

Effectiveness of Pre-Hospital Blood Products

University of Warwick is collaborating with researchers at the NIHR Surgical Reconstruction and Microbiology Research Centre (SRMRC) to support a ground-breaking new study to investigate the effectiveness of giving patients... read more

Milestone-based Assessment for Internal Medicine Residents

Milestone-based Assessment for Internal Medicine Residents

This Cross-Sectional study investigates how well correlated are 2 academic rating systems measuring medicine residents' training and whether medical knowledge scores correlate with American Board of Internal Medicine... read more

Uncontrolled Bleeding Stopped By Injectable Viscous Hydrogel

Uncontrolled Bleeding Stopped By Injectable Viscous Hydrogel

A new study describes a novel embolic agent for endovascular embolization procedures that has a hemostatic activity comparable to that of metallic coils, the current gold standard. The nanocomposite STBs are injected through... read more

Plazomicin Succeeds in Phase 3 cUTI and CRE Trial

Plazomicin Succeeds in Phase 3 cUTI and CRE Trial

Plazomicin an antibiotic being developed to fight multidrug-resistant bacterial infections, has met the primary objective of noninferiority compared with meropenem in a phase 3 registration trial among patients with complicated... read more

Anesthesiologist reaction time increased after night call

Anesthesiologist reaction time increased after night call

For anesthesiologists, reaction time increases after a night call, with greater increases seen in correlation with reliance on avoidance as a coping mechanism. Post-call psychomotor vigilance test mean reaction time decreased... read more