COVID-19 Pandemic Effect on the Incidence and Survival Outcomes of EMS-witnessed OHCA

While other international studies have observed higher incidence and reduced survival in non-EMS-witnessed out-of-hospital cardiac arrest (OHCA) during the COVID-19 pandemic, this study did not identify any significant impacts... read more

COVID-19 Pandemic Effect on the Incidence and Survival Outcomes of EMS-witnessed OHCA

Improving Intubation Performance with Airway Registries

Airway registries are used as a crucial tool to monitor and improve intubation performance and patient care. ED airway registries inform and document the efficacy of quality improvement initiatives to improve intubation performance... read more

Improving Intubation Performance with Airway Registries

IHCA Variation Throughout the Day

We observed higher rates of hospital cardiac arrest (IHCA), and poorer outcomes at night. However, in those admitted to ICU, this variation was absent. This suggests patient factors and processes of care issues contribute... read more

IHCA Variation Throughout the Day

Post-discharge Care Using Telemedicine: Pre-pandemic vs. Pandemic Care

Expansion of virtual post-discharge visits to include all patients and telephone calls did not negatively impact rates of 30-day post-discharge hospital encounters. Offering tele-health options for post-discharge follow-up... read more

Post-discharge Care Using Telemedicine: Pre-pandemic vs. Pandemic Care

Impact of Variations in the Nursing Care Supply-Demand Ratio on Postoperative Outcomes and Costs

Improving surgical outcomes is a priority during the last decades because of the rising economic health care burden. The adoption of enhanced recovery programs has been proven to be part of the solution. In this context,... read more

Impact of Variations in the Nursing Care Supply-Demand Ratio on Postoperative Outcomes and Costs

Continuous Positive Airway Pressure Usage During COVID-19

We confirm that use of early continuous positive airway pressure (CPAP) with high-flow output combined with an "ad hoc" algorithm to inform the decision to intubate is a valid and safe strategy for respiratory support in... read more

Continuous Positive Airway Pressure Usage During COVID-19

Cardiovascular Mortality Post Burn Injury

Survivors from burn injury, especially young males, are at increased long-term risk of death from cardiovascular disease. Increased screening and counseling pertaining to lifestyle factors should be standard management post-burn... read more

Cardiovascular Mortality Post Burn Injury

Postoperative Pulmonary Complications in the ENIGMA II Trial

Respiratory complications remain among the most common and serious adverse outcomes of major surgery. In the Australian and New Zealand Audit of Surgical Mortality, postoperative pneumonia accounted for 44% of infective... read more

Postoperative Pulmonary Complications in the ENIGMA II Trial

Sick Children Identification in Acute Care Settings

At the heart of every pediatric consultation is the clinician’s responsibility to determine ‘is this child sick?’ In pediatrics illustrative language communicates a clinical picture of the child before us. When... read more

Sick Children Identification in Acute Care Settings

Rising Mortality in COVID-19 Patients Supported With ECMO

We aimed to describe practice patterns and outcomes in patients with extracorporeal membrane oxygenation (ECMO) support throughout the coronavirus 2019 (COVID-19) pandemic, with the hypothesis that mortality would improve... read more

Rising Mortality in COVID-19 Patients Supported With ECMO

Ultrasound-Guided Infraclavicular Axillary Vein vs. Internal Jugular Vein Cannulation in Critically Ill Mechanically Ventilated Patients

No difference was found between the real-time ultrasound-guided out-of-plane cannulation of the IJV and the infraclavicular real-time ultrasound-guided in-plane cannulation of the AXV. Both techniques are equally efficient... read more

Ultrasound-Guided Infraclavicular Axillary Vein vs. Internal Jugular Vein Cannulation in Critically Ill Mechanically Ventilated Patients

Early evaluation of heart rate variability can predict the outcome of patients in the ICU

The study evaluated the use of heart rate variability (HRV) to predict the outcome of patients in the ICU. HRV is a way to evaluate the cardiac effects of the autonomic nervous system, and a relation between HRV and outcome... read more

Early evaluation of heart rate variability can predict the outcome of patients in the ICU

Acute Effects of Ketamine on ICP in Children With Severe TBI

In this retrospective, exploratory study, intracranial pressure (ICP) did not increase following ketamine administration. In the setting of a guidelines-based protocol, ketamine was associated with a reduction in ICP during... read more

Acute Effects of Ketamine on ICP in Children With Severe TBI

Baricitinib or Tocilizumab for Severe COVID-19 Treatment

Pharmacologic treatment of COVID-19 has continued to evolve since the onset of the pandemic, and yet many questions remain about optimal treatment. Medicine strives to provide evidence-based guidance on treatments, but... read more

Baricitinib or Tocilizumab for Severe COVID-19 Treatment

6 Days Higher-Dose Ivermectin vs. Placebo on Time to Sustained Recovery in COVID-19 Outpatients

Among a largely vaccinated outpatient population with mild to moderate COVID-19, treatment with ivermectin, with a targeted maximum dose of 600 μg/kg daily for 6 days, compared with placebo was not shown to improve time... read more

6 Days Higher-Dose Ivermectin vs. Placebo on Time to Sustained Recovery in COVID-19 Outpatients

The effect of a multi-faceted quality improvement program on paramedic intubation success in the critical care transport environment

A multi-faceted advanced airway management (AAM) quality improvement program (QIP) resulted in statistically significant increase in intubation first pass success rates (FPS) rates and a non-significant improvement in DASH-1A... read more

The effect of a multi-faceted quality improvement program on paramedic intubation success in the critical care transport environment

Improving Access to ECMO for OHCA

Mobile teams using transport accessibility frameworks and principles can significantly improve patient access for out-of-hospital cardiac arrest (OHCA) compared to in-hospital extracorporeal cardiopulmonary resuscitation... read more

Improving Access to ECMO for OHCA

Remote Ischemic Conditioning in Septic Shock

The treatment known as RECO did not significantly reduce the severity of organ failure as measured by the mean daily SOFA (sequential organ failure assessment) score from the start of the study to day 4 in patients with septic... read more

Remote Ischemic Conditioning in Septic Shock

Molnupiravir Improves Recovery Time in COVID-19 Patients at High Risk of Severe Outcomes

This analysis of a large randomized trial involving people who are at high risk of experiencing severe outcomes from COVID-19 and who had been vaccinated against SARS-CoV-2 infection found that adding molnupiravir to usual... read more

Molnupiravir Improves Recovery Time in COVID-19 Patients at High Risk of Severe Outcomes

Family Presence During Cardiac Arrest Resuscitation

This systematic review identified four key findings. Firstly, there was a lack of high-quality evidence on the impact of family presence during resuscitation on patient outcomes. Secondly, family members had varied... read more

Family Presence During Cardiac Arrest Resuscitation

Time from Infiltrate on Chest Radiograph to VV ECMO in COVID-19 Affects Mortality

Venovenous extracorporeal membrane oxygenation (VV ECMO) has been used to treat severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome; however, patient selection criteria have evolved throughout the... read more

Time from Infiltrate on Chest Radiograph to VV ECMO in COVID-19 Affects Mortality

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest

Targeting a mean arterial blood pressure of 77 mm Hg or 63 mm Hg in patients who had been resuscitated from cardiac arrest did not result in significantly different percentages of patients dying or having severe disability... read more

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest