Tag: study
Using Critical Ultrasound To Predict Early Diagnosis of ICU-acquired Weakness in Septic Patients
This study uncovered pivotal indicators for predicting the occurrence of ICUAW in septic patients. Despite no significant difference in age, gender, BMI, BSA, or SOFA scores between the two groups, the significant differences... read more
Prolonged vs. Intermittent Infusion of Meropenem For Patients with Severe Infection
Prolonged infusion of meropenem is more effective than intermittent infusion in reducing mortality, improving clinical outcomes, and enhancing microbial eradication, without increasing adverse events. These benefits are... read more
Zosyn vs. Efepime: Which One Is Safer?
While both piperacillin-tazobactam and cefepime are commonly used to treat infections caused by Pseudomonas aeruginosa in hospitalized patients, there is a concern that piperacillin-tazobactam may lead to acute kidney injury... read more
Pleural Drainage, Clinical Characteristics, and Management Strategies in the Perioperative Fontan Patient
Prolonged pleural drainage and chylothorax are common in postoperative Fontan patients and are associated with increased morbidity and mortality. Multiple medical and interventional treatment strategies exist and vary between... read more
Developing a Rapid Screening Tool for High-risk ICU Sepsis Patients
This study demonstrates that machine learning-based prediction models for sepsis can enhance clinical outcomes through accurate risk assessment during the critical first 24h of ICU admission. Despite healthcare system... read more
Impact of Time to Catheter-Based Therapy on Outcomes in Acute Pulmonary Embolism
Early catheter-based therapie (CBT) was associated with improved clinical outcomes in patients with acute intermediate-risk pulmonary embolism (PE). The composite PE shock score may help identify patients who will benefit... read more
Severe Sepsis-associated AKI and Outcomes
These results demonstrate an association between an index episode involving SA-AKI and the composite outcome in a defined population. Identification of this group may allow intensive nephrology follow-up and secondary... read more
High cDPP3 Predicts Mortality and Need for Organ Support in Cardiogenic Shock
The present study confirms that circulating dipeptidyl peptidase 3 (cDPP3) and its kinetics are associated with 30-day mortality and the need for organ support in a large and diverse population of CS. The prognostic value... read more
Atypical Presentation of Pulmonary Embolism in Patients with Refractory Hypoxemia and Dyspnea
Pulmonary embolism (PE) should be strongly considered in patients presenting with refractory hypoxemia and dyspnea, even in the absence of clinical signs of deep vein thrombosis (DVT). This study highlights the importance... read more
Inflammatory Markers and Severity in COVID-19 Patients with Clostridioides Difficile Co-Infection
The interplay of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection and Clostridioides difficile infection (CDI) poses a critical clinical challenge. The resultant inflammatory milieu and its impact... read more
Assessing TBI with Transorbital Sonography
Transorbital sonography (TOS) represents an innovative tool for neurological assessment. It has been validated that the presence or absence of eyelid edema does not compromise the accuracy of ultrasound-based pupillary function... read more
Implementing Bedside Percutaneous Tracheostomy and PUG Team to Reduce LOS
Thousands of critically ill patients every year in the United States receive tracheostomy and gastrostomy procedures. Recent research has investigated the benefits of a combined team approach to these procedures, with associated... read more
Landiolol vs. Esmolol – Efficacy and Safety in Critically Ill Patients
Landiolol provides superior heart rate control in critically ill patients with tachycardia compared to Esmolol, without increasing vasopressor requirements during the first 24 h. Findings from ScvO2 levels and PCO2 gap... read more
Sodium Bicarbonate In In-Hospital and Out-of-Hospital Cardiac Arrest
Cardiac arrest is a common cause of death worldwide. Sodium bicarbonate (SB) has commonly been used during cardiopulmonary resuscitation (CPR) to correct metabolic acidosis (MA). However, the existence of evidence about its... read more
Temporal Trends of RSV-Associated US ICU Admissions
Wide variations in regional and seasonal patterns in hospital and ICU admissions were noted in children with respiratory syncytial virus–associated acute respiratory illness across the United States. Results from our... read more
Immunocompromised People May Not Produce Enough Protective Antibodies Against RSV After Vaccination
This study demonstrated heterogeneous antibody response to respiratory syncytial virus (RSV) vaccines among immunocompromised persons. In contrast to universal seroconversion and preF IgG fold rises greater than 10 in immunocompetent... read more
Impact of Extended-course Oral Nirmatrelvir/Ritonavir in Established Long COVID
Extended courses of nirmatrelvir/ritonavir may have meaningful benefits for some people with Long COVID but not others. We encourage researchers to study how and why nirmatrelvir/ritonavir benefits some and what course length... read more
Prediction of AKI in ICU Patients Based on Interpretable Machine Learning
The machine learning model described in this study is capable of accurately predicting the onset of AKI in ICU patients up to 24 hours in advance. Validated within the MIMIC-IV and MIMIC-III databases, the model demonstrates... read more
Decision Support Tool in the Prehospital Setting for Acute Chest Pain
Using the Atellica VTLi in the EMS setting for the analysis of troponin I in acute chest pain patients is feasible. However, the instruments are unfamiliar for most EMS personnel, and a break-in period should be allowed for... read more
Fluid Bolus Therapy with 20% Albumin vs. Crystalloid-based Regimen
In this trial involving adult patients undergoing cardiac surgery with cardiopulmonary bypass, 20% albumin fluid bolus therapy (FBT) compared to crystalloid FBT did not decrease the occurrence of acute kidney injury (AKI).... read more
New Insights on CRRT for ARDS
In recent times, the applications of continuous renal replacement therapy (CRRT) beyond kidney‐related conditions have been progressively increasing, and its implementation in randomized controlled trials (RCTs) specifically... read more
