Assessing the Risk of Poor Clinical Outcomes in Preterm Neonates with Late-onset Sepsis

A predictive calculator for assessing the risk of poor clinical outcomes in preterm neonates with late-onset sepsis (LOS) has been developed. By leveraging readily available clinical data at the time of blood culture collection,... read more

Patients Under Mechanical Ventilation Are Highly Perceptive

This meta-synthesis provides insights into the perception of intensive care patients under Mechanical Ventilation (MV) who are continuously observing their own lives. This process is complex and involves a highly differentiated... read more

Hemoglobin Glycation Index vs. Adverse Outcomes in Critically Ill Patients with Myocardial Infarction

Based on the MIMIC-IV database, this study found that lower HGI is significantly associated with an increased risk of short-, mid- and long-term all-cause mortality in critically ill myocardial infarction (MI) patients. As... read more

Predicting SA-AKI Mortality Using XGBoost Algorithm

The integration of advanced techniques with the XGBoost algorithm yielded a highly accurate and interpretable model for predicting Sepsis-Associated Acute Kidney Injury (SA-AKI) mortality across diverse populations. It... read more

Pharmacokinetics of Opioid Infusions in the Adult ICU Setting

To counter these pharmacokinetics (PKs) alterations, new therapeutic avenues must be further explored in the ICU to individualize opioid infusions. Embase, MEDLINE, PubMed, CINAHL, and Evidence-Based Medicine Reviews (EBMR)... read more

Clinical Efficacy of Nafamostat Mesylate-assisted CRRT Therapy in SA-AKI Patients

Nafamostat Mesylate (NM)-assisted continuous renal replacement therapy (CRRT) therapy significantly improves the therapeutic efficacy of patients with sepsis-associated acute kidney injury (SA-AKI). This combined approach... read more

ARDS Predictors in ICU Patients with Sepsis Using Dynamic Immune Indicator Changes

This study underscores the pivotal role of dynamic immune indicator changes in predicting acute respiratory distress syndrome (ARDS) development among ICU sepsis patients. By incorporating immune cell and immunoglobulin dynamics... read more

Alcohol Consumption Association with the Risk of Bacterial Infection and Pneumonia

Alcohol consumption has a nonlinear J-shaped dose–response association with the risk of acquiring and dying due to bacterial infection and pneumonia, where moderate consumption between one-half and four UK units per day... read more

Pre-ICU Statin Use, AKI and in Hospital Mortality in Sepsis Patients

Pre-ICU statin therapy is associated with a lower risk of acute kidney injury (AKI), and improved in-hospital survival among obese patients with sepsis, suggesting its potential role as a protective measure in this high-risk... read more

Factors Influencing the Mortality of Patients with Subarachnoid Hemorrhage in the ICU

Spontaneous subarachnoid hemorrhage (SAH) is a prevalent condition for those between the ages of 50 and 60 years, with a high mortality rate in severe cases. The findings of this study indicate that a history of loss... read more

Epidemiology of Myocardial Injury in Trauma Patients

Pathological Troponin concentration elevation occurs in 7% of all trauma patients and it identifies the seriously injured high-risk cohort with worse outcomes than expected based on injury severity. The timing of the... read more

Fungal Infections Surveillance and Prevention in the NICU

It was determined that colonization and development of invasive mycoses among newborns are most often caused by Candida sp., while the detection of filamentous fungi remains sporadic. The etiological role of Malassezia... read more

Prognostic Predictor Using Lactate-to-Albumin Ratio in Patients with Cirrhosis and Sepsis

Lactate-to-albumin ratio (LAR) is strongly associated with poor prognosis in patients with cirrhosis and sepsis. LAR is a promising prognostic marker that provides clinicians with a simple and effective tool for risk... read more

Mortality Predictor with sPAP in Elderly Critically Ill with Severe COVID-19 Pneumonia

Mortality in general ARDS patients remains high, with many experiencing long-lasting sequelae. Numerous studies have been conducted to identify predictors of mortality in COVID-19 patients, particularly regarding right ventricular... read more

Low Decent Work Perception Among PICU Nurses

The level of decent work perception among PICU nurses in general hospitals is relatively low and is influenced by factors such as age, educational level, professional title, average monthly income, and personal experience... read more

Diastolic Dysfunction Increases AKI Rick in COVID-19 Patients

Diastolic dysfunction increases the risk of acute kidney injury (AKI) in patients with severe COVID-19. Using point-of-care ultrasound (PoCUS) to assess left ventricular diastolic function in the ICU may be a useful parameter... read more

Barriers to Early Mobilization Perceived by PICU Staff

There is a need to implement educational and organizational interventions in the PICU to overcome the identified barriers. Training staff, clarifying roles and responsibilities, as well as promoting a culture that values... read more

Asthma Course Evaluation in PICU Due to Severe Asthma Exacerbation

Admission to the PICU due to severe asthma exacerbation not only increases the risk of recurrent asthma exacerbations but also serves as a risk factor for stepping up maintenance treatment according to GINA guidelines during... read more

Exploring the Effectiveness of HFNC in the Neurointensive Care Unit

The high flow nasal cannula (HFNC) is becoming increasingly prevalent in both adult and pediatric general intensive care. Despite limited reporting in neurocritical care, we have successfully utilized HFNC in our cohort... read more

Cytomegalovirus Infection in Immunocompromised ICU Patients: What Intensivists Need To Know

Cytomegalovirus (CMV) infection and disease in critically ill immunocompromised patients pose a unique challenge for intensivists. The broad spectrum of clinical presentations and the difficulty in distinguishing CMV-related... read more

Unlocking the Predictive Power of Nutritional Scores in Septic Patients

This study highlights the significant prognostic utility of nutritional status evaluation in septic patients admitted to internal medicine wards. Among the tools evaluated, the mNUTRIC score—likely because of its dual... read more

Dynamic Nomogram for AKI Prediction in ICU Patients with AHF

After strict screening, 1338 patients with acute heart failure (AHF) were included in the derivation set, and 3,129 in the validation set. Sepsis, use of human albumin, age, mechanical ventilation, aminoglycoside administration,... read more