Tag: study
Predictors of Weaning Failure in Ventilated ICU Patients
Predictors for weaning failure are widely researched. To date, 145 predictors have been investigated with varying intensity in 140 studies that are in line with the current weaning definition. It is no longer just individual... read more
Risk Factors for Secondary Organizing Pneumonia and Acute Fibrinous and Organizing Pneumonia in Patients with COVID-19 Pneumonia
Based on our findings, we observed that age ≥50 years, diabetes mellitus, and severe hypoxemia on admission (SpO2 ... read more
Extended Prone Position and 90-Day Mortality in Mechanically Ventilated Patients with COVID-19
Extended prone positioning (PP) was associated with improved 90-d survival in subjects with COVID-19 undergoing mechanical ventilation for severe ARDS. These findings suggest the potential benefit of EPP in the management... read more
Skin Decontamination to Prevent ICU Infections
Intensive care unit (ICU)-acquired infections can be serious complications of medical care of critically ill patients. Despite multiple tested and implemented preventive measures for such infections, their incidence is persistently... read more
Septic Shock in the Prehospital Setting
Septic shock (SS) is a potential life-threatening condition in which an early identification and immediate therapy stand out as the main cornerstones to improve survival chance; in this context, emergency medical services... read more
Protocolized Fluid Balance Neutralization During CRRT
Bitker et al. report the GO NEUTRAL randomized clinical trial results, which investigated fluid balance neutralization guided by functional hemodynamic monitoring (FHM) protocol versus a standard of care in critically ill... read more
Relationship between Concentrations of Oxygen and Levels of Oxidative Stress in Patients Receiving Oxygen Therapy for Severe COVID-19 Pneumonia
We evaluated the potential of high-flow oxygen therapy to increase oxidative stress and inflammation in COVID-19 patients. Our observation of decreased MDA levels when transitioning hypertensive patients from high-flow to... read more
Outcomes and inflammation changes in different types of immunocompromised patients with critically ill COVID-19 admitted to ICU
Critically ill COVID-19 patients admitted to the ICU exhibit distinct clinical outcomes based on their immunosuppression status, with cancer patients facing the highest mortality rate due to variations in inflammatory responses... read more
Pulmonary Barotrauma in COVID-19 Patients: Experience From a Tertiary University Hospital
Mechanical ventilation (MV) in COVID-19 patients is often complicated with pulmonary barotrauma. The aim of this study was to determine the incidence and risk factors associated with the development of pulmonary barotrauma... read more
Delirium and Weakness Acquired in the ICU: Individual and Combined Effects on 90-Day Mortality in Survivors of Critical Illness
Mortality is substantially high among critically ill survivors who experience both delirium and weakness, although no additive effect on mortality was observed when these conditions occur together. Our findings highlight... read more
Distinct Immune Profiles and Clinical Outcomes in Sepsis Subphenotypes Based on Temperature Trajectories
Sepsis subphenotypes identified using the universally available measurement of body temperature had distinct immune profiles. Hypothermic patients, who had the highest mortality rate, also had the lowest levels of most pro-... read more
Octenidine Bathing Effective in Preventing ICU-acquired Primary Bacteremia
EFFECT has demonstrated that octenidine is effective at preventing primary bacteremia. The emphasis lies among Gram-positive bacteria and common skin commensals. As part of a robust bundle strategy, octenidine can serve... read more
Blood Eosinophils Matter in Post-COVID-19 Pneumonia
Preliminary results showed that a eosinophil increase during hospitalization could be a potential predictor of pulmonary sequelae in surviving patients after COVID-19 pneumonia. Despite the protective role of eosinophils,... read more
A Retrospective Closed Cohort Study on Distribution of Multidrug-Resistant Bacteria in VAP and its Impact on Patient Outcome
Gram-negative organisms, particularly Klebsiella and Acinetobacter, were the main multidrug-resistant (MDR) ventilator-associated pneumonia (VAP) culprits. MDR-VAP exhibited higher morbidity and mortality. A study... read more
Accuracy of Continuous Glucose Monitoring Systems in ICU Patients
In this scoping review of CGM accuracy in the ICU, we found great diversity in accuracy reporting. Accuracy varied depending on CGM and comparator, and may be better for intravascular CGM and potentially lower during hypoglycemia. We... read more
