Tag: study
Outcomes of Patients with COVID-19 and Relationship with Lung Ultrasound Signs
In patients with COVID-19 pneumonia, Lung Ultrasound Signs (LUS) signs, including the aeration score, were related to respiratory and systemic symptoms 1 month after ultrasound screening examination. In these patients, a... read more
Use of Biomarkers to Identify AKI to Help Detect Sepsis in Patients with Infection
Use of the urinary (tissue inhibitor of metalloproteinases-2) × (insulin-like growth factor binding protein 7) test could identify acute kidney injury in patients with infection, possibly helping to detect sepsis, nearly... read more
Evaluation of Time-Limited Trials Among Critically Ill Patients with Advanced Medical Illnesses and Reduction of Nonbeneficial ICU Treatments
In this study, a quality improvement intervention that trained physicians to communicate and plan ICU care with family members of critically ill patients in the ICU using TLTs was associated with improved quality of family... read more
Relationship Between Skeletal Muscle Area and Density and Clinical Outcome in Adults Receiving VV-ECMO
Low skeletal muscle index at the commencement of venovenous extracorporeal membrane oxygenation (VV-ECMO) was associated with a longer duration of venovenous extracorporeal membrane oxygenation, whereas preserved skeletal... read more
A Controlled Trial of Methylprednisolone in COVID-19 Pneumonia
The use of corticosteroids in patients with pneumonia secondary to COVID-19 has been a controversially hot topic, particularly early on in the pandemic. Prior evidence seen in Severe Acute Respiratory Syndrome (SARS) and... read more
Clinical Features and Predictors in Critically Ill COVID-19 Patients
We aim to describe a case series of critically and non-critically ill COVID-19 patients in Singapore. This was a multicentered prospective study with clinical and laboratory details. Details for fifty uncomplicated COVID-19... read more
Role of N-Acetylcysteine in Non-acetaminophen-related Acute Liver Failure
N-acetylcysteine (NAC) is well known to emergency medicine physicians as the antidote in acute acetaminophen ingestion. The scope of use for this medication beyond that is often not considered, such as in other etiologies... read more
Expanding Post-Discharge Readmission Metrics in Patients with COPD
Of 1,384,025 hospitalizations, 11,304 encounters from 8097 patients met criteria to be index hospitalizations. Most index hospitalizations were inpatient hospitalizations (74.8%) versus observation hospitalizations (25.2%).... read more
Confirming a Pulse during Resuscitation
Much has been written about using ultrasound in cardiac arrest. The REASON study found that identification of cardiac standstill in PEA or asystole is correlated with almost no chance of meaningful recovery and can assist... read more
Prone Position in Intubated, Mechanically Ventilated COVID-19 Patients
During the COVID-19 pandemic, prone position has been widely adopted to treat mechanically ventilated patients with respiratory failure. The majority of patients improved their oxygenation during prone position, most likely... read more
Effects of Ventilatory Rescue Therapies on the Cerebral Oxygenation of COVID-19 Patients
A new study by Masimo published in Critical Care evaluated the impact of a variety of rescue therapies on the systemic and cerebral oxygenation of mechanically ventilated COVID-19 patients suffering from acute respiratory... read more
Mayo Clinic Critical and Neurocritical Care Board Review
Mayo Clinic Critical and Neurocritical Care Board Review is an all-inclusive review of the pathophysiology and care of the neurocritically ill and critically ill patient. The book reviews the core major critical care... read more
IVCDV is not a reliable indicator of preload responsiveness
During mechanical ventilation with Vt = 6 mL/kg, the effects of passive leg raising (PLR) can be assessed by changes in pulse pressure variation (PPV). If inferior vena cava diameter (IVCDV) is used, it should be expressed... read more
Effect of intubation timing on clinical outcomes of critically ill patients with COVID-19
The synthesized evidence suggests that timing of intubation may have no effect on mortality and morbidity of critically ill patients with COVID-19. These results might justify a wait-and-see approach, which may lead to fewer... read more
Technical Aspects and Clinical Applications in Lung Ultrasound
Lung ultrasound is increasingly used in emergency departments, medical wards, and critical care units—adult, pediatric, and neonatal. In vitro and in vivo studies show that the number and type of artifacts visualized change... read more
Hemodynamic Profiling utility using Pulmonary Artery Catheters in Cardiogenic Shock
PAC usage in cardiogenic shock (CS) is being revitalized by recent positive analyses of large registry and administrative databases. To realize the full potential of pulmonary artery catheters (PAC), more research is urgently... read more
Comparison of Two Delayed Strategies for RRT initiation for severe AKI
Delaying renal replacement therapy (RRT) for some time in critically ill patients with severe acute kidney injury (AKI) and no severe complication is safe and allows optimisation of the use of medical devices. Major uncertainty... read more
Feasibility and Accuracy of ED Frailty Identification in Older Trauma Patients
This prospective study has demonstrated that screening for frailty in older major trauma patients within the Emergency Department is feasible and accurate using Clinical Frailty Scale (CFS). Patients age 65 years and... read more
Isavuconazole vs. Voriconazole for Antifungal Prophylaxis in Lung Transplant Recipients
Isavuconazole was effective and well tolerated as antifungal prophylaxis following lung transplantation. A single-center, retrospective study of patients who received isavuconazole (September 2015–February 2018) or voriconazole... read more
Multicomponent Non-pharmacological Intervention on Delirium and Sleep Quality in SICU
Delirium is a deleterious condition affecting up to 60% of patients in the surgical intensive care unit (SICU). Few SICU-focused delirium interventions have been implemented, including those addressing sleep-wake disruption,... read more
Drug Treatments for COVID-19
Corticosteroids and interleukin-6 inhibitors probably confer important benefits in patients with severe covid-19. Janus kinase inhibitors appear to have promising benefits, but certainty is low. Azithromycin, hydroxychloroquine,... read more
COVID-19 vaccines effective for pregnant women, likely protect their babies too
COVID-19 mRNA vaccines are extremely effective at protecting pregnant and lactating women against the virus, and likely provide protection for their babies as well, according to a study published March 25 in the American... read more
