Tag: study
Host Endothelial, Epithelial and Inflammatory Response in ICU COVID-19 Patients
These studies demonstrate that, unlike other well-studied causes of critical illness, endothelial dysfunction may not be characteristic of severe COVID-19 early after ICU admission. Pathways resulting in elaboration of acute... read more
Clinical Trial of Therapeutics for Severely Ill Hospitalized COVID-19 Patients Begins
A new Phase 3 trial to test the safety and efficacy of therapeutics for COVID-19 has begun enrolling patients hospitalized with life-threatening cases of COVID-19, including those with acute respiratory failure. The trial... read more
A Practical Integrated Radiomics Model Predicting COVID-19 Hospitalization
It has been widely demonstrated that radiological imaging significantly contributes to diagnosing and monitoring pulmonary and systemic involvement of patients affected by COVID-19 using different techniques like chest X-ray... read more
Association of Low Baseline Diaphragm Muscle Mass With Prolonged Mechanical Ventilation and Mortality Among Critically Ill Adults
In this study, low baseline diaphragm muscle mass in critically ill patients was associated with prolonged mechanical ventilation, complications of acute respiratory failure, and an increased risk of death in the hospital. A... read more
Normalization of blood clotting characteristics using prothrombin complex concentrate, fibrinogen and FXIII in an albumin based fluid
Combinations of coagulation factor concentrates suspended in albumin solutions can restore thromboelastometry parameters in the absence of plasma. This kind of artificial colloid fluids with coagulation-restoring characteristics... read more
Post‑COVID‑19 Syndrome in Outpatients
Background Some patients experience long-term symptoms after COVID-19, but data on outpatients with mild-to-moderate COVID-19 are scarce. Objective To describe persisting symptoms more than 3 months after infection in PCR-confirmed... read more
10 Scientific Reasons in Support of Airborne SARS-CoV-2 Transmission
Heneghan and colleagues' systematic review, funded by WHO, published in March, 2021, as a preprint, states: "The lack of recoverable viral culture samples of SARS-CoV-2 prevents firm conclusions to be drawn about airborne... read more
Optimal Needle Position for Decompression of Tension Pneumothorax
Tension Pneumothorax (TP) can occur as a potentially life-threatening complication of chest trauma. With the risk of respiratory and cardiac arrest, an immediate temporizing intervention for this condition is required by... read more
90 Day Outcomes of COVID-19 Patients in European ICUs
This communication delineates outcomes in COVID-19 patients in the context of ARDS severity, ventilatory management, and variables associated with mortality on a 90-day follow-up for subgroups of patients after ICU admission.... read more
Effect of Infusion Set Replacement Intervals on Catheter-related Bloodstream Infections
The optimal duration of infusion set use to prevent life-threatening catheter-related bloodstream infection (CRBSI) is unclear. We aimed to compare the effectiveness and costs of 7-day (intervention) versus 4-day (control)... read more
Co-infection in Critically Ill Patients with COVID-19
During previous viral pandemics, reported co-infection rates and implicated pathogens have varied. In the 1918 influenza pandemic, a large proportion of severe illness and death was complicated by bacterial co-infection,... read more
Patient’s Clinical Presentation and CPPopt Availability: Any Association?
In this retrospective multicenter study, none of the selected admission and treatment variables were related to the CPPopt yield. The median CPPopt yield was 80.7% (interquartile range 70.9–87.4%). None of the selected... read more
Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19 Patients
Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate... read more
Outcomes of Patients with COVID-19 and Relationship with Lung Ultrasound Signs
In patients with COVID-19 pneumonia, Lung Ultrasound Signs (LUS) signs, including the aeration score, were related to respiratory and systemic symptoms 1 month after ultrasound screening examination. In these patients, a... read more
Use of Biomarkers to Identify AKI to Help Detect Sepsis in Patients with Infection
Use of the urinary (tissue inhibitor of metalloproteinases-2) × (insulin-like growth factor binding protein 7) test could identify acute kidney injury in patients with infection, possibly helping to detect sepsis, nearly... read more
Evaluation of Time-Limited Trials Among Critically Ill Patients with Advanced Medical Illnesses and Reduction of Nonbeneficial ICU Treatments
In this study, a quality improvement intervention that trained physicians to communicate and plan ICU care with family members of critically ill patients in the ICU using TLTs was associated with improved quality of family... read more
Relationship Between Skeletal Muscle Area and Density and Clinical Outcome in Adults Receiving VV-ECMO
Low skeletal muscle index at the commencement of venovenous extracorporeal membrane oxygenation (VV-ECMO) was associated with a longer duration of venovenous extracorporeal membrane oxygenation, whereas preserved skeletal... read more
A Controlled Trial of Methylprednisolone in COVID-19 Pneumonia
The use of corticosteroids in patients with pneumonia secondary to COVID-19 has been a controversially hot topic, particularly early on in the pandemic. Prior evidence seen in Severe Acute Respiratory Syndrome (SARS) and... read more
Clinical Features and Predictors in Critically Ill COVID-19 Patients
We aim to describe a case series of critically and non-critically ill COVID-19 patients in Singapore. This was a multicentered prospective study with clinical and laboratory details. Details for fifty uncomplicated COVID-19... read more
Role of N-Acetylcysteine in Non-acetaminophen-related Acute Liver Failure
N-acetylcysteine (NAC) is well known to emergency medicine physicians as the antidote in acute acetaminophen ingestion. The scope of use for this medication beyond that is often not considered, such as in other etiologies... read more
Expanding Post-Discharge Readmission Metrics in Patients with COPD
Of 1,384,025 hospitalizations, 11,304 encounters from 8097 patients met criteria to be index hospitalizations. Most index hospitalizations were inpatient hospitalizations (74.8%) versus observation hospitalizations (25.2%).... read more
Confirming a Pulse during Resuscitation
Much has been written about using ultrasound in cardiac arrest. The REASON study found that identification of cardiac standstill in PEA or asystole is correlated with almost no chance of meaningful recovery and can assist... read more
