Tag: study
Management of Patients Supported with VA-ECMO
Veno-arterial extracorporeal membrane oxygenation (VA ECMO) application in adult patients has significantly increased in recent years. The Extracorporeal Life Support Organization (ELSO) registry includes more than 39,000... read more
Postoperative Liver Dysfunction After Lung Transplantation with Extracorporeal Life Support and 1-year Mortality
In this retrospective cohort study, we identified an elevated 1-year mortality rate among patients who developed postoperative liver dysfunction, as defined by the presence of HLD, DILI-like symptoms, and cholestasis subsequent... read more
Mental Health in the First Year After ICU-treated Sepsis
Existing data on the prevalence of mental health impairments (MHI) following sepsis and intensive care are based predominantly on self-reported symptoms assessed by using questionnaires, small sample sizes, and clinically... read more
Association Between the Lactate-to-Albumin Ratio (LAR) Index and AKI Risk in Critically Ill Patients with Sepsis
Lactate-to-albumin ratio (LAR) is an emergency predictive indicator of sepsis-related mortality. An elevated LAR is associated with poor outcomes in critically ill patients. However, its predictive value for acute kidney... read more
Which Antimicrobial Treatment for Patients with Bloodstream Infection During ECMO Support?
Enterococcus sp. was incriminated in about a third of BSI among patients with ECMO support. High appropriateness would only be obtained with piperacilline/tazobactam or carbapenems in association with vancomycin while 3rd... read more
Enhanced Prediction of ICU LOS Using a Stack Ensemble of Machine Learning Models
The Length of Stay (LoS) refers to the time between a patient's hospital admission and discharge. LoS is considered to increase as the complexity of the disease increases. A prolonged stay in the Intensive Care Unit (ICU)... read more
Risk Factors for Subsequent LRTI Following an Infant RSV Hospitalization
Fifteen percent of infants experience at least one other medically attended lower respiratory tract infection (MA LRTI) after an respiratory syncytial virus (RSV) hospitalization in the same season, and approximately half... read more
Predicting Sudden Decrease in Oxygenation in Mechanically Ventilated ICU Patients as a Surrogate Marker for ARDS
Acute Respiratory Distress Syndrome (ARDS) is a life-threatening form of respiratory failure characterized by widespread lung inflammation that severely impairs oxygenation. Affecting millions of patients worldwide, ARDS... read more
Unlocking the Predictive Power of Nutritional Scores in Septic Patients
The study highlights the mNUTRIC score's practicality and reliability in assessing nutritional and inflammatory risks in septic patients, particularly in non-ICU settings. These findings suggest its potential utility... read more
Enteric Gram-negative Infections on Lung Transplant Clinical Outcomes
Lung transplant recipients (LTR) with more complicated post-operative courses were more likely to develop enteric gram-negative (GNR) infections which led to increased post-transplant morbidities. Pre-transplant GNR colonization... read more
Cumulative Fluid Balance During the First Three ICU Days in Septic Patients with Heart Failure
In septic patients with HFpEF, positive fluid balance of CFB-day1 might improve the prognosis of patients. However, from the second day, fluid overload was associated with poor prognosis. Therefore, we propose that on... read more
AKI and Mortality Predictors of Systemic Autoimmune Diseases and COVID-19
The present study highlights renal parameters and outcomes associated with various systemic autoimmune diseases and COVID-19. Patients who presented with low oxygen saturation (... read more
Prescribing Patterns and Effectiveness of Ceftolozane/Tazobactam in Immunosuppressed Patients
Treatment with Ceftolozane/Tazobactam (C/T) resulted in a high rate of clinical success in this real-world cohort of immunosuppressed patients, despite dosing that frequently deviated from labelled dosing. Pseudomonas... read more
Multi-dimensional Outcomes Following ECPR
Recent trials suggested that extracorporeal cardio-pulmonary resuscitation (ECPR) with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) or "ECMELLA" (VA-ECMO plus Impella) may improve short-term survival and neurological... read more
VEGFR1 Genetic Regulation During Sepsis and Association with ARDS Susceptibility
We identified biologically relevant protein quantitative trait loci (pQTLs) of vascular endothelial growth factor receptor 1 (VEGFR1) levels during sepsis in TCF20 and identified CYP2D6 as the gene more biologically implicated.... read more
Bundling Procedures in Critically Ill Trauma Patients and ICU LOS
Intubated trauma patients who presented with certain mechanisms (gunshot wounds (GSW), pedestrian struck), received blood transfusions, or exhibited severe/profound ISS may be more likely to receive immediate bundled lines... read more
APRV vs. BIPAP Ventilation in COVID-19 Associated ARDS
Despite of higher mean tidal volumes and higher mean airway pressures in airway pressure release ventilation (APRV) vs. biphasic positive airway pressure (BIPAP), both modes did not present an increased risk of volu- or barotrauma... read more
Cytokeratin-18 Levels in COVID-19 Patients
This study analyzed 176 samples, including 63 ICU-admitted patients and 88 non-ICU-admitted patients. A substantial difference was found between the AST and CK-18 levels of the patients receiving ICU care and those who did... read more
Ventilator Associated Pneumonia in ICU: Identification, Evaluation and Prevention
This study highlights the significant prevalence of Pseudomonas aeruginosa (PA) as a major bacterial pathogen causing ventilator-associated pneumonia (VAP) in ICU patients, with a high detection rate of 71.7% in tested patients,... read more
New Insights: Mortality in Nosocomial Lower Respiratory Tract Infections
This multicenter, multinational study conducted in Europe and Latin America sheds light on the clinical landscape of nLRTI, which continues to be an essential issue in the context of critical care. We provide insights... read more
ICU-AW in Cardiogenic Shock Patients Requiring Mechanical Circulatory Support
This study provides insights into the characteristics of intensive care unit-acquired weakness (ICU-AW) in patients with Cardiogenic Shock (CS) requiring mechanical circulatory support (MCS). ICU-AW frequently occurred... read more
New Insights: Inhaled Nitric Oxide in Severe COVID-19 Patients
This study provides novel insights into the use of inhaled nitric oxide in severe ARDS COVID-19 patients. Specifically, we demonstrate that the iNO effect of oxygenation improvement is delayed with a prolonged feature that... read more
