Vitamin C for Sepsis Suffers a Setback. Or a Step-Forward. It’s Complicated

The CITRIS-ALI study found no difference in primary outcomes among patients with sepsis treated with vitamin C versus placebo. But there was a difference in a secondary outcome - overall mortality. When it comes to sepsis... read more

Brainstem Responses Can Predict Death and Delirium in ICU Sedated Patients

Assessment of brainstem responses is feasible in sedated critically ill patients and loss of selected responses is predictive of mortality and altered mental status. 72 patients were included in the initial group and 72... read more

Brainstem Responses Can Predict Death and Delirium in ICU Sedated Patients

20 Percent of Patients Hospitalized for Cardiac Arrest Readmitted Within a Month

This cohort study found increased rates of readmission among patients who survived cardiac arrest. Early follow-up with health care professionals may enable timely management of both cardiac and general medical conditions... read more

20 Percent of Patients Hospitalized for Cardiac Arrest Readmitted Within a Month

Effect of Vitamin C Infusion on Organ Failure in Patients With Sepsis and ARDS

In this preliminary study of patients with sepsis and Acute Respiratory Distress Syndrome (ARDS), a 96-hour infusion of vitamin C compared with placebo did not significantly improve organ dysfunction scores or alter markers... read more

Effect of Vitamin C Infusion on Organ Failure in Patients With Sepsis and ARDS

What Should You Know About Evidence-Based Guidelines?

As healthcare professionals we want to provide patients the best possible medical care. Prehospital care, like the rest of medicine, is constantly changing, since the research performed today will shape the medical care we... read more

Driving Pressure Is Associated with Outcome during Assisted Ventilation in ARDS

In patients with Acute Respiratory Distress Syndrome (ARDS), plateau pressure, driving pressure, and respiratory system compliance can be measured during assisted ventilation, and both higher driving pressure and lower compliance... read more

Driving Pressure Is Associated with Outcome during Assisted Ventilation in ARDS

Long-Term Outcomes and Health Care Utilization after Prolonged Mechanical Ventilation

Critically ill patients who undergo mechanical ventilation in an ICU for longer than 21 days have high in-hospital mortality and greater postdischarge mortality, health care utilization, and health care costs compared with... read more

Long-Term Outcomes and Health Care Utilization after Prolonged Mechanical Ventilation

Low-dose Atrial Natriuretic Peptide for Prevention or Treatment of AKI

Theoretically, atrial natriuretic peptide (ANP), especially low-dose ANP, is beneficial in acute kidney injury (AKI). In this study, we examined whether low-dose ANP is effective in preventing or treating AKI by conducting... read more

Low-dose Atrial Natriuretic Peptide for Prevention or Treatment of AKI

Impact of Delayed Admission to ICUs on Mortality of Critically Ill Patients

When the number of patients who require intensive care is greater than the number of beds available, intensive care unit (ICU) entry flow is obstructed. This phenomenon has been associated with higher mortality rates... read more

Impact of Delayed Admission to ICUs on Mortality of Critically Ill Patients

Outcomes of ARDS in Mechanically Ventilated Patients With Cirrhosis

Acute respiratory distress syndrome (ARDS) is common in mechanically ventilated patients with cirrhosis but is not independently associated with increased mortality. The mean age in 181 eligible patients was 53 ± 11 years;... read more

Outcomes of ARDS in Mechanically Ventilated Patients With Cirrhosis

The Effect of Vitamin C on Clinical Outcome in Critically Ill Patients

In a mixed population of ICU patients, vitamin C administration is associated with no significant effect on survival, length of ICU or hospital stay. In cardiac surgery, beneficial effects on postoperative atrial fibrillation,... read more

The Effect of Vitamin C on Clinical Outcome in Critically Ill Patients

Accuracy of Quick Sequential Organ Failure Assessment Score to Predict Sepsis Mortality

Overall, quick Sequential Organ Failure Assessment score outperforms systemic inflammatory response syndrome in predicting sepsis outcome, but quick Sequential Organ Failure Assessment score has relative strengths/weaknesses... read more

Accuracy of Quick Sequential Organ Failure Assessment Score to Predict Sepsis Mortality

Improving Outcomes for ICU Survivors

In response to the many challenges faced by ICU survivors today, there has been an increasing need to relieve this burden. Despite that many clinical trials have been implemented to find new strategies, post-intensive care... read more

Improving Outcomes for ICU Survivors

Blood Cultures From Arterial Catheters Reliable for Detection of Bloodstream Infection in PICUs

Cultures of arterial catheter–drawn blood are reliable for the detection of bloodstream infection in PICUs. The study group consisted of 138 patients admitted to the general or cardiac PICU in 2014–2015 who met the following... read more

Blood Cultures From Arterial Catheters Reliable for Detection of Bloodstream Infection in PICUs

The Speaker Gender Gap at Critical Care Conferences

There is a speaker gender gap at critical care conferences, with male faculty outnumbering female faculty. This gap is more marked among physician speakers than those speakers representing nursing and allied health professionals.... read more

The Speaker Gender Gap at Critical Care Conferences

Microbial Strategies to Reduce Pathogens and Drug Resistance in Clinical Settings

Healthcare‐associated infections (HAIs) are a global concern, affecting all western hospitals, and profoundly impairing the clinical outcome of up to 15% of all hospitalized patients. Persistent microbial contamination... read more

Microbial Strategies to Reduce Pathogens and Drug Resistance in Clinical Settings

Blood Culture Results Before and After Antimicrobial Administration in Patients With Severe Sepsis

Among patients with severe manifestations of sepsis, initiation of empirical antimicrobial therapy significantly reduces the sensitivity of blood cultures drawn shortly after treatment initiation. Of 3,164 participants... read more

Blood Culture Results Before and After Antimicrobial Administration in Patients With Severe Sepsis

Occupational Therapy in the ICU

The role of occupational therapists in ICU rehabilitation is not currently well established. Current interventions in the ICU are dominated by physical rehabilitation with a growing role in communication and delirium... read more

Occupational Therapy in the ICU