Tag: study
The role of pleural pressure and airway closure during mechanical ventilation
Related to our paper, Van Egmond et al. highlighted key physiological concepts we must be aware of. We believe, however, that the described physiological com-plexity has limited impact on the daily use of esophageal pressure... read more
Two weaning strategies for NIV in COPD patients with ARF
Non-Invasive Ventilation (NIV) is a crucial therapy for managing acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) with hypercapnic respiratory failure. Research has shown that NIV can decrease the rate... read more
Incidence of AKI and attributive mortality in ARDS randomized trials
The development of acute kidney injury (AKI) after the acute respiratory distress syndrome (ARDS) reduces the chance of organ recovery and survival. The purpose of this study was to examine the AKI rate and attributable mortality... read more
Prone Positioning During ECMO for Severe ARDS
The ongoing debate on optimal extracorporeal membrane oxygenation (ECMO) care emphasizes the need for rigorous investigation, acknowledging the value of observational data in routine The PRONECMO study, with its pragmatic... read more
Sepsis Mortality Among ICU Patients with Hematological Malignancy
Over the past two decades, there have been substantial improvements in mortality in hematological malignancy patients with sepsis, including across all levels of illness severity and in patients requiring mechanical ventilation.... read more
Impact of a Rounding Checklist Implementation in the Trauma ICU on Clinical Outcomes
We aimed to evaluate the effectiveness of an intensive care unit (ICU) round checklist, FAST HUGS BID (Feeding, Analgesia, Sedation, Thromboembolic prophylaxis, Head-of-bed elevation, Ulcer prophylaxis, Glycemic control,... read more
Prior Exposure to ACEi Increased Cardiovascular Response to Angiotensin-II
Prior exposure to RAS-inhibiting medications was associated with an altered RAS profile and cardiovascular response to angiotensin-II treatment in patients with catecholamine-refractory vasodilatory shock. ACE-inhibitor... read more
Vasopressor Reduction Effect of Polymyxin B Hemoperfusion
This study aimed to evaluate the effect of polymyxin B hemoperfusion (PMX-HP) in patients with peritonitis-induced septic shock who still required high dose vasopressors after surgical source control. A total of 338 patients... read more
Methylene Blue in Sepsis and Septic Shock
This systematic review and meta-analysis evaluated the effect of MB in three RCTs. They found that MB treatment significantly reduced time to vasopressor discontinuation, days on mechanical ventilation, and length of ICU... read more
Cardiac Index and Heart Rate as Prognostic Indicators for Mortality in Septic Shock
Our retrospective study shows that monitoring cardiac index and heart rate in patients with septic shock may help predict the organismal response and hemodynamic consequences, as well as the prognosis. Thus, healthcare providers... read more
Fluid Personalization and Vasopressor Decisions in Early Sepsis Management
In this randomized vignette survey study of US critical care clinicians, we found that fluid volume already received was associated with the largest changes in decisions to administer additional fluids or initiate vasopressors... read more
AKI Risk Factors in ICU Patients Using Colistin
Colistin, an antibiotic of polymyxin group, has recently been increasingly used in the treatment of multidrug resistant gram-negative bacteria. However, it has serious adverse effects such as acute kidney injury (AKI). We... read more
Clinical Outcomes in Critically Ill COVID-19 Unvaccinated Patients Admitted to the ICU
We analyzed unvaccinated critically ill ICU patients with COVID-19 and interpreted their demographics, clinical characteristics, comorbidities, and laboratory data upon ICU admission for a better understanding of their impact... read more
Haloperidol vs. Placebo in ICU Patients with Delirium
We assessed long-term outcomes in acutely admitted adult patients with delirium treated in intensive care unit (ICU) with haloperidol versus placebo. In acutely admitted adult ICU patients with delirium, haloperidol treatment... read more
Critical Hypertension in Trauma Patients Following Prehospital Emergency Anesthesia
Delivery of prehospital emergency anesthesia (PHEA) to seriously injured trauma patients risks hemodynamic fluctuation. In adult trauma patients undergoing PHEA, 11.9% of patients experienced post-PHEA critical hypertension.... read more
Ilofotase Alfa Doesn’t Improved Survival Among Critically Ill Patients with SA-AKI
Sepsis-associated acute kidney injury (SA-AKI) in patients admitted to an intensive care unit is associated with significant morbidity and mortality. There is currently no pharmaceutical treatment. Although we found no... read more
Efficacy of High-Flow Nasal Cannula Oxygen Therapy in Patients with AHRF
This study suggests that high-flow nasal cannula (HFNC) therapy in general respiratory wards may be a potential rescue therapy for patients with respiratory failure. Electrical impedance tomography (EIT) potentially monitors... read more
