Tag: study
Nutrition Therapy – One Size Does Not Fit All
A review paper published in Critical Care highlights the importance of employing targeted nutritional care for critically ill patients. The sad truth, according to the article, is that current ICU nutrition delivery worldwide... read more
Initial Crystalloid Resuscitation in Sepsis and Septic Shock
Ludwig Lin, MD, speaks with Daniel E. Leisman, BS, about the article, "Patterns and Outcomes Associated With Timeliness of Initial Crystalloid Resuscitation in a Prospective Sepsis and Septic Shock Cohort," published in Critical... read more
Machine Learning Model Predicts Sepsis in ICU Patients 12 Hours Before Diagnosis
A machine learning model accurately predicted the onset of sepsis in ICU patients four to 12 hours prior to clinical recognition in a recent study. The observational cohort study used data from more than 31,000 admissions... read more
When Do Confounding by Indication and Inadequate Risk Adjustment Bias Critical Care Studies?
In critical care observational studies, when clinicians administer different treatments to sicker patients, any treatment comparisons will be confounded by differences in severity of illness between patients. We sought to... read more
Considerations for Physicians Using Ketamine for Sedation of Children in EDs
Ketamine use in emergency departments (EDs) for procedural sedation and analgesia is becoming increasingly common. However, few studies have examined patient factors related to adverse events associated with ketamine. This... read more
The EM Educator Series: Sepsis in the ED
These posts provide brief mini-cases followed by key questions to consider while working. The featured questions provide important learning points for those working with you, as well as vital items to consider in the evaluation... read more
Effect of a National Standard for Deteriorating Patients on Intensive Care Admissions Due to Cardiac Arrest in Australia
The main objective of this study is to assess whether a national standard for improving care of deteriorating patients affected ICU admissions following cardiac arrests from hospital wards. Introducing a national standard... read more
Six-month Outcome of Immunocompromised Severe ARDS Patients Rescued by ECMO
Recently diagnosed immunodeficiency is associated with a much better prognosis in ECMO-treated severe ARDS. However, low 6-month survival of our large cohort of immunocompromised patients supports restricting ECMO to patients... read more
How Do You Feel? Subjective Perception of Recovery
Long-term subjective and objective outcome appears good in the majority of cardiac arrest survivors. Specific functional and cognitive impairments were found in patients reporting unsatisfactory recovery. Subjective recovery... read more
Healthcare Utilization and Infection in the Week Prior to Sepsis Hospitalization
Over 45% of sepsis patients had clinician-based encounters in the week prior to hospitalization with an increasing frequency of diagnoses for acute infection and antibiotic use in the outpatient setting. These presepsis encounters... read more
Central Venous Catheter – Which Needle?
A prospective randomised trial comparing insertion success rate and incidence of catheterisation-related complications for subclavian venous catheterisation using a thin-walled introducer needle or a catheter-over-needle... read more
Serum Lactate Upon Emergency Department Arrival as Predictor of 30-day In-Hospital Mortality
Despite of numerous evidences that elevated serum lactate levels were associated with unfavorable outcomes, there have been no study demonstrated an optimal cutoff of serum lactate in unselected patients. This study was aimed... read more
The Fallacy of Time-to-Intervention Studies
We are barraged by time-to-intervention studies (door-to-balloon time, time-to-antibiotics, door-to-needle, etc.). However, it must be kept in mind that these studies are purely correlational in design. Such studies cannot... read more
Effect of Standardized Handoff Curriculum on Improved Clinician Preparedness in the ICU
The UW-IPASS standardized handoff curriculum was perceived to improve intensive care provider preparedness and workflow. IPASS-based curricula represent an important step forward in communication standardization efforts and... read more
Development of Dementia in Patients with Femoral Neck Fracture Who Experience Postoperative Delirium
It remains unclear to what extent postoperative delirium (POD) affects the incidence of dementia in hip fracture patients, and the methods used to detect delirium and dementia require validation. The aim of this study was... read more
Potentially Modifiable Risk Factors for Long-Term Cognitive Impairment After Critical Illness
Long-term cognitive impairment is common in survivors of critical illness. Little is known about the etiology of this serious complication. We sought to summarize current scientific knowledge about potentially modifiable... read more
TAC on Computed Tomography and the Risk of COPD Progression
Total Airway Count (TAC) may reflect the airway-related disease changes that accumulate in the “quiet” zone in early/mild Chronic Obstructive Pulmonary Disease (COPD), indicating that TAC acquired with commercially available... read more
Antimicrobials for the Treatment of Drug-Resistant Acinetobacter Baumannii Pneumonia in Critically Ill Patients
This Bayesian network meta-analysis demonstrated the comparative effectiveness of fifteen antimicrobial treatments for drug-resistant A. baumannii pneumonia in critically ill patients. For survival benefit, SUL appears to... read more
Urine Test Developed to Test for Tuberculosis
An international team of researchers has developed a urine test that can be used to detect tuberculosis (TB) in human patients. Alessandra Luchini and her team have developed a urine test for TB that gives results in 12 hours.... read more
Early Identification of Acute Respiratory Distress Disorder in the Absence of Positive Pressure Ventilation
Almost all patients with pulmonary bilateral infiltrates and a PaO2/FIO2 less than or equal to 300 mm Hg under standard oxygen fulfilled the acute respiratory distress syndrome criteria under noninvasive ventilation within... read more
A Comparison of the qSOFA and SIRS Criteria for the Diagnosis of Sepsis and Prediction of Mortality
Several studies were published to validate quick-SOFA (qSOFA), namely in comparison with Systemic Inflammatory Response Syndrome (SIRS) criteria. We performed a systematic review and a meta-analysis with the aim of comparing... read more
Effect of Lung Recruitment and Titrated PEEP vs Low PEEP on Mortality in Patients with ARDS
In patients with moderate to severe Acute Respiratory Distress Syndrome (ARDS), a strategy with lung recruitment and titrated Positive End-Expiratory Pressure (PEEP) compared with low PEEP increased 28-day all-cause mortality.... read more
