Long-term Outcomes Associated With Implantable Cardioverter Defibrillator in Adults With CKD

In a large, contemporary, noninterventional study of community-based patients with heart failure and Chronic Kidney Disease (CKD), ICD placement was not significantly associated with improved survival but was associated with... read more

Long-term Outcomes Associated With Implantable Cardioverter Defibrillator in Adults With CKD

Long-term Recovery Following Critical Illness in an Australian Cohort

Almost all data on 5-year outcomes for critical care survivors come from North America and Europe. The aim of this study was to investigate long-term mortality, physical function, psychological outcomes and health-related... read more

Long-term Recovery Following Critical Illness in an Australian Cohort

Adjuvant Therapies in Critical Care: Music Therapy

Emerging from the perioperative and oncology fields, music therapy (MT) and patient-directed music interventions (PDMI) have recently garnered interest in the area of critical care. The main goal of these music-based adjuvant... read more

Adjuvant Therapies in Critical Care: Music Therapy

Receiving a Letter of Condolence After Loss of a Loved One in the ICU

This study describes the benefits of receiving a letter of condolence; mainly, it humanizes the medical institution (feeling of support, confirmation of the role played by the relative, supplemental information). However,... read more

Receiving a Letter of Condolence After Loss of a Loved One in the ICU

Sepsis Incidence: A Population-Based Study

The incidence of sepsis with organ dysfunction is higher than most previous estimates independent of definition. The inclusion of all inpatients started on intravenous antibiotic treatment of sepsis in a population makes... read more

Sepsis Incidence: A Population-Based Study

Pharmacokinetics of meropenem in septic patients on sustained low-efficiency dialysis

The aim of the study was to describe the population pharmacokinetics (PK) of meropenem in critically ill patients receiving sustained low-efficiency dialysis (SLED). We found a relevant PK variability for meropenem in patients... read more

Pharmacokinetics of meropenem in septic patients on sustained low-efficiency dialysis

General Anesthesia a Viable Sedation Strategy for Thrombectomy in Stroke

An analysis of a New York registry with 1174 patients who underwent thrombectomy showed a correlation between general anesthesia and death. Several other studies that only compared embolectomies done with and without general... read more

General Anesthesia a Viable Sedation Strategy for Thrombectomy in Stroke

Cerebral Autoregulation in the Prediction of Delayed Cerebral Ischemia and Clinical Outcome in Poor-Grade Aneurysmal Subarachnoid Hemorrhage Patients

High initial pressure reactivity index, presumably reflecting early brain injury, but not oxygen reactivity index, was associated with delayed cerebral ischemia and worse clinical outcome in poor-grade subarachnoid hemorrhage... read more

Cerebral Autoregulation in the Prediction of Delayed Cerebral Ischemia and Clinical Outcome in Poor-Grade Aneurysmal Subarachnoid Hemorrhage Patients

Oral Versus Intravenous Antibiotics for the Treatment Of Bone and Joint Infection

Oral antibiotic therapy is non-inferior to IV therapy when used during the first six weeks in the treatment for bone and joint infection, as assessed by definitive treatment failure within one year of randomisation. These... read more

Oral Versus Intravenous Antibiotics for the Treatment Of Bone and Joint Infection

The Association Between ARDS Hospital Case Volume and Mortality

In this cohort, at both an individual- and hospital-level, higher acute respiratory distress syndrome hospital case volume is associated with lower acute respiratory distress syndrome hospital mortality. We analyzed 2,686... read more

The Association Between ARDS Hospital Case Volume and Mortality

Prevalence of Pulmonary Embolism in Patients With Syncope

The results of the present study confirm that pulmonary embolism (PE) is rarely identified in patients presenting to the ED with syncope. Although PE should be considered as a differential diagnosis in every patient, not... read more

Prevalence of Pulmonary Embolism in Patients With Syncope

Outcomes of Ethics Consultations in Adult ICUs

Our review identified outcome-based assessment as the predominant measure used to report effectiveness of clinical ethics consultation consultations. In particular, clinical ethics consultation decreased ICU length of stay... read more

Outcomes of Ethics Consultations in Adult ICUs

Inspiratory Muscle Training Does Not Improve Clinical Outcomes in 3-week COPD Rehabilitation

The value of inspiratory muscle training (IMT) in pulmonary rehabilitation in chronic obstructive pulmonary disease (COPD) is unclear. The RIMTCORE (Routine Inspiratory Muscle Training within COPD Rehabilitation) randomised... read more

Inspiratory Muscle Training Does Not Improve Clinical Outcomes in 3-week COPD Rehabilitation

Training Approaches for the Deployment of a Mechanical Chest Compression Device

Pit-crew training, compared with standard training, did not improve team deployment of a mechanical chest device in a simulated cardiac arrest scenario. Twenty teams participated in this study, each comprising three clinicians.... read more

Training Approaches for the Deployment of a Mechanical Chest Compression Device

Variation of Poorly Ventilated Lung Units Measured by EIT to Dynamically Assess Recruitment

Assessing alveolar recruitment at different positive end-expiratory pressure (PEEP) levels is a major clinical and research interest because protective ventilation implies opening the lung without inducing overdistention.... read more

Variation of Poorly Ventilated Lung Units Measured by EIT to Dynamically Assess Recruitment

The Utility of ICU Readmission as a Quality Indicator and the Effect of Selection

Intensive care readmission rates are used to signal quality, yet it is unclear whether they represent poor quality in the transition of care from the ICU to the ward, patient factors, or differences in survival of the initial... read more

The Utility of ICU Readmission as a Quality Indicator and the Effect of Selection

Prognostic Effects of Delirium Motor Subtypes in Hospitalized Older Adults

One in three acutely ill hospitalized older adults who suffered hypo-active or mixed delirium died in the hospital. Clinicians should be aware that hypo-active symptoms of delirium, whether shown exclusively or in alternation... read more

Prognostic Effects of Delirium Motor Subtypes in Hospitalized Older Adults

Physician Genders and the Likelihood of ICU Admission in Hospital with Restricted ICU Bed Capacity

Despite the evidence that the patient gender is an important component in the intensive care unit (ICU) admission decision, the role of physician gender and the interaction between the two remain unclear. We demonstrated... read more

Physician Genders and the Likelihood of ICU Admission in Hospital with Restricted ICU Bed Capacity