Tag: study
Hospital Factors May Influence NIV Outcomes Even in Low-Evidence Use
Strong evidence supports use of noninvasive ventilation (NIV) for patients with respiratory distress from chronic obstructive pulmonary disease and heart failure – i.e., strong evidence conditions (SECs). A new study of... read more
High Flow Nasal Cannula Use Outside of the ICU – Factors Associated with Failure
High FiO2 requirements, history of intubation, and cardiac co-morbidity are associative predictors of HFNC failure. Bronchiolitis patients may be treated with HFNC outside of the ICU with lower odds of failure. Two hundred... read more
Review of Strategies to Reduce CLABSI and CAUTI in Adult ICUs
Central line–associated bloodstream infection (CLABSI) and catheter-associated urinary tract infection (CAUTI) are costly and morbid. Despite evidence-based guidelines, Some intensive care units (ICUs) continue to have... read more
Perspectives of Survivors, Families and Researchers on Key Outcomes for Research in ARF
There is heterogeneity among the outcomes evaluated in studies of survivors of acute respiratory failure (ARF). Patient, family and researcher groups supported inclusion of outcome domains that fit within the PICS framework.... read more
Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe hemorrhage
Antifibrinolytics reduce death from bleeding in trauma and post-partum haemorrhage. We examined the effect of treatment delay on the effectiveness of antifibrinolytics. We obtained data for 40,138 patients from two randomised... read more
A simple algorithm for the identification of clinical COPD phenotypes
This study aimed to identify simple rules for allocating chronic obstructive pulmonary disease (COPD) patients to clinical phenotypes identified by cluster analyses.Data from 2409 COPD patients of French/Belgian COPD cohorts... read more
Accuracy and Applications of Lung Ultrasound to Diagnose VAP
Lung ultrasound (LUS) is an accurate tool to diagnose community-acquired pneumonia. However, it is not yet an established tool to diagnose ventilator-associated pneumonia (VAP). Small subpleural consolidations and dynamic... read more
RRT Modality in the ICU and Renal Recovery at Hospital Discharge
In this large retrospective study, intermittent hemodialysis as an initial modality was associated with lower renal recovery at hospital discharge among patients with acute kidney injury, although the difference seems somewhat... read more
Shock Trauma to Study Body Cooling for Patients in Cardiac Arrest from Massive Bleeding
The R Adams Cowley Shock Trauma Center at the University of Maryland has opened a clinical trial to study whether rapidly cooling the body temperature of patients whose hearts stop due to massive blood loss will give surgeons... read more
Frequency of pulmonary embolism amongst patients admitted for first-time syncope
All patients admitted to an inpatient service for first-time syncope from the emergency departments of 11 Italian hospitals from 2012-2014 were evaluated for pulmonary embolism. Pulmonary embolism was found in 17.3% of patients... read more
Higher levels of tau protein found in children with early onset psychosis
New research shows that levels of a certain type of the Alzheimer's disease-related tau protein are higher in patients aged 18 years and under suffering early onset psychosis (EOP).... read more
An Expert Consensus Statement on Physical Rehabilitation After Hospital Discharge
A consensus-based framework for optimal physical therapy (PT) after hospital discharge is proposed. Future research should focus on feasibility testing of this framework, developing risk stratification tools and validating... read more
PAH Associated With Systemic Lupus Erythematosus
Patients with SLE-PAH have an overall 5-year survival rate of 83.9% after the Pulmonary Arterial Hypertension (PAH) diagnosis. Anti-SSA/SSB antibodies may be a risk factor for PAH, and the presence of anti-U1-RNP antibodies... read more
A Measure of Physicians’ Motivation to Adopt Medical Devices
This is the first reliable and valid scale to measure physicians' adoption motivation. Future adoption studies assessing the individual level should include the PMA scale to obtain more information about the role of physicians’... read more
Assessing Usefulness of Randomized Clinical Trials
In the pyramid of evidence based medicine randomized controlled trials (RCTs) are considered to be one of the most reliable study designs when evaluating the cause and effect of treatment modalities. When evaluating randomized... read more
Furosemide in the Treatment of Acute Pulmonary Edema
CHF is a common problem in the US with over 5 million patients carrying the diagnosis and 500,000 new diagnoses each year.1 Cardiogenic acute pulmonary edema (APE) occurs when blood backs up into the pulmonary vasculature... read more
Core Outcome Measures for Clinical Research in ARF Survivors
This Core Outcome Measurement Set is recommended for use in all clinical research evaluating acute respiratory failure (ARF) survivors after hospital discharge. In the future, researchers should evaluate measures for outcomes... read more
New-Onset Atrial Fibrillation in the Critically Ill
Kyle Enfield, MD, speaks with Travis J. Moss, MD, MSc, and J. Randall Moorman, MD, about the article, "New-Onset Atrial Fibrillation in the Critically Ill," published in the May 2017 issue of Critical Care Medicine. Drs.... read more
Higher PEEP versus Lower PEEP Strategies for Patients with ARDS
Use of higher positive end-expiratory pressure (PEEP) is unlikely to improve clinical outcomes among unselected patients with ARDS. We identified eight randomized trials comparing higher versus lower PEEP strategies, enrolling... read more
Is this critically ill patient elderly or too old?
Life expectancy is increasing in industrialized countries. It is forecast that in the European Union 24.4 million people will be older than 85 years in 2040, more than doubling from the 10.4 million seen in 2010. In parallel,... read more
Understanding Adrenal Crisis
Approximately 5–17 cases of adrenal crisis (AC) occur per 100 patient years in patients with primary or secondary adrenal insufficiency (AI). The mortality rate is estimated to be between 0.5% and 2%. Norwegian data indicate... read more
Alarm Fatigue in ICU Addressed in Two Studies
Alarm fatigue within the intensive care unit (ICU) can negatively impact patient safety and lead to life-threatening events. Researchers from Harlem Hospital and Maimonides Medical Center aimed to identify solutions fight... read more
