Tag: therapy
The Emotional Toll of Treating Victims of Violence
Hospital leaders are implementing several techniques to address the lasting trauma of disaster emergencies. Hospital disaster drills often focus on transporting patients to the emergency department and moving them into the... read more
Meta-Analysis of Therapeutic Hypothermia for Traumatic Brain Injury in Adult and Pediatric Patients
Therapeutic hypothermia is a likely beneficial treatment following TBI in adults, improving both neurologic outcomes and decreasing mortality rates. Our work suggests that the optimal management strategy to improve both morbidity... read more
Role of Combination Antimicrobial Therapy for Vancomycin‐Resistant Enterococcus faecium Infections
Enterococcus species are the second most common cause of nosocomial infections in the United States and are particularly concerning in critically ill patients with preexisting comorbid conditions. Rising resistance to antimicrobials... read more
Factors influencing physical activity and rehabilitation in survivors of critical illness
Eighty-nine papers were included. Five major themes and 28 sub-themes were identified, encompassing: (1) patient physical and psychological capability to perform physical activity, including delirium, sedation, illness severity,... read more
Electronic Dura Mater Meddling in the Central Nervous System
This review of preclinical applications assesses the potential of the electronic dura mater to deliver electrical and chemical stimulation to targeted areas of the central nervous system for extended periods. Soft neural... read more
Assessing Postoperative Pulmonary Complications After Noncardiothoracic Surgery
In this multicenter study in 1202 American Society of Anesthesiologists physical status 3 patients undergoing noncardiothoracic surgery requiring 2 hours or more of general anesthesia with mechanical ventilation, at least... read more
POCT for emergency assessment of coagulation in patients treated with direct oral anticoagulants
Hemochron Signature Point-of-care testing (POCT) can be a fast and reliable alternative for guiding emergency treatment during rivaroxaban and dabigatran therapy. It allows the rapid identification of a relevant fraction... read more
Carotid Stenting Technology Has More Appeal
Ten-year follow-up from the CREST trial and 5-year follow-up from the ACT I study, presented at least year's International Stroke Conference, showed that carotid artery stenting (CAS) holds up well over the long term... read more
Thromboprophylaxis after Knee Arthroscopy and Lower-Leg Casting
The results of our trials showed that prophylaxis with low-molecular-weight heparin for the 8 days after knee arthroscopy or during the full period of immobilization due to casting was not effective for the prevention of... read more
Management of Sepsis and Septic Shock
The best approach for hemodynamic therapy for sepsis has become more uncertain as evidence has accumulated. This extends even to the degree to which clinicians should use intravenous fluids as a foundation for resuscitation... read more
Statins for Primary Prevention
A recent issue of JAMA contains the latest US Preventive Services Task Force (USPSTF) recommendation statement on statins for prevention of cardiovascular disease in adults, along with the accompanying evidence report and... read more
First deep brain stimulation surgery on stroke patient
Cleveland Clinic performed the nation's first deep brain stimulation surgery on a stroke patient. This is part of an ongoing clinical trial that’s evaluating whether DBS can improve movement after a stroke. Only 10... read more
Patient Achieves Remission With CAR-T Cell Therapy for Aggressive Brain Tumors
A case study published in the December 29 issue of the New England Journal of Medicine outlines the results of a patient treated with his own genetically modified CAR-T cells, using central memory T cells, a stem-cell-like... read more
Antibiotic Resistance just became more complex
Bacteria that are susceptible to antibiotics can survive when enough resistant cells around them are expressing an antibiotic-deactivating factor. This new take on how the microbial context can compromise antibiotic therapy.... read more
Clinical challenge in IBD expanded by Systemic inflammation
More targeted antibody therapies carry the potential to transform how physicians treat inflammatory bowel disease. However, management can become less clear when IBD patients present with extra-intestinal manifestations.... read more
Think Sepsis and Act Fast
New attention to sepsis including revised definitions, updated guidelines, and new CMS reporting requirements aims to save lives through prevention and prompt and effective management of infections. CDC released a new Vital... read more
Upright CT for lung cancer therapy planning used at Chicago Proton Center
The Northwestern Medicine Chicago Proton Center will be the first proton center in the U.S. to use P-Cure new P-ARTIS CT on patients being treated for lung cancer. Traditionally, patients lie flat on their backs during CT... read more
Therapy Implications for Immunomodulation After Ischemic Stroke
Despite significant advances towards a better understanding of the pathophysiology of ischemic stroke-induced immunosuppression and SAP in recent years, many unanswered questions remain. The true incidence and outcomes of... read more
Three-year mortality in 30 day survivors of critical care with AKI
Acute kidney injury was not an independent risk factor for 3-year mortality among 30-day survivors. Increased 3-year mortality among patients with AKI who survive critical illness may not be related to AKI per se, but rather... read more
Antibiotic therapy advances in the critically ill
Key issues related to antibiotic management in the critically ill, including problems associated with timing, duration, and dosing of antibiotics. The authors highlighted the importance of early diagnosis of infection and... read more
Drugs Don’t Cut Trastuzumab-Tied Left Ventricular Remodeling
The researchers found that the drugs were well tolerated, with no serious adverse events reported. The indexed left ventricular end diastolic volume increased in patients treated with perindopril, bisoprolol, and placebo... read more
