Tag: therapy
Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure
Among patients receiving recommended therapy for heart failure, those in the empagliflozin group had a lower risk of cardiovascular death or hospitalization for heart failure than those in the placebo group, regardless of... read more
Plasma Exchange in Critically Ill COVID-19 Patients
The spectrum of coronavirus disease 2019 (COVID-19) ranges from asymptomatic infection to respiratory failure and death of patients. Severely affected patients may develop a cytokine storm-like clinical syndrome with multi-organ... read more
Prone Positioning in Non-intubated Patients with COVID-19
As the COVID-19 pandemic has put severe stress and strain on the capacity of hospitals around the world, concerted efforts have been made to evaluate therapeutics aimed at preventing the need for mechanical ventilation. The... read more
Acid-Base, Fluids, and Electrolytes Made Ridiculously Simple
A brief, highly readable book providing the clinician with a straightforward approach to solving even the most complex, acid-base, fluid, and electrolyte problems. Useful to medical students, interns and residents, nurses... read more
Safety and Feasibility of Early Physical Therapy for Patients on ECMO
With a highly trained multidisciplinary team and a focus on restoring function, it is feasible and safe to deliver early rehabilitation including standing and ambulation to patients on extracorporeal membrane oxygenation... read more
A Randomised Trial of High-flow Nasal Cannula in Infants with Moderate Bronchiolitis
In patients with moderate bronchiolitis, there was no evidence of lower rate of escalating respiratory support among those receiving HFNC therapy. The analyses included 268 patients among the 2621 infants assessed for... read more
Anaphylatoxin C5a Impairs Phagocytosis by Neutrophils
This study provides new insight into the mechanisms underlying immunocompromise in critical illness and suggests novel avenues for therapy and prevention of nosocomial infection. Critically ill patients are at heightened... read more
Massive PE with Intra-hospital Cardiac Arrest and Full Recovery of RV Function after vaECMO
The concept of vaECMO treatment alone might be a valuable alternative in selected patients with massive PE and cardiogenic shock, in whom thrombolytic therapy might not unload the RV fast enough. We present a case of a... read more
Endovascular Therapy for Acute Ischemic Stroke During COVID-19 Pandemic
The evaluation and treatment of acute large vessel occlusion stroke present many challenges during the COVID-19 era. It may be difficult to screen stroke patients for COVID-19 symptoms because of encephalopathy or aphasia.... read more
Inhaled Pulmonary Vasodilators
Confusion between inhaled versus intravenous routes for pulmonary vasodilators. For optimal clinical benefit (especially regarding oxygenation), these agents must be given via an inhaled route. The misconception that inhaled... read more
Cost Analysis of Adjunctive Hydrocortisone Therapy for Septic Shock
Using adjunctive hydrocortisone therapy yields a significant monetized benefit based on inputs from the Adjunctive Corticosteroid Treatment in Critically Ill Patients with Septic Shock and Activated Protein C and Corticosteroids... read more
Approach to New Fever or Rigors in the ICU Patient
Failure to recognize neutropenic fever as a separate entity that requires immediate treatment. Routinely ordering urinalysis and sputum cultures (for most patients, this will only lead to false-positive results and unnecessary... read more
Harm of IV High-Dose Vitamin C Therapy in Adult Patients
There is no consistent evidence that IV high-dose vitamin C therapy is more harmful than placebo in double-blind randomized controlled trials. However, reports of oxalate nephropathy, hypernatremia, glucometer error, and... read more
High Risk of Thrombosis in Patients With Severe SARS-CoV-2 Infection
Despite anticoagulation, a high number of patients with ARDS secondary to COVID-19 developed life-threatening thrombotic complications. Higher anticoagulation targets than in usual critically ill patients should therefore... read more
