Vaccine-Induced Prothrombotic Immune Thrombocytopenia After AstraZeneca COVID-19 Vaccination

Vaccine-Induced Prothrombotic Immune Thrombocytopenia After AstraZeneca COVID-19 Vaccination

The United Kingdom, European Union, and Scandinavian countries have reported that the AstraZeneca COVID-19 vaccine appears to be associated with rare cases of serious blood clots, including blood clots in the brain. These... read more

Key Topics in Critical Care

Key Topics in Critical Care

High quality critical care medicine is a crucial component of advanced health care. Completely revised and updated, Key Topics in Critical Care, Second Edition provides a broad knowledge base in the major areas of critical... read more

RAPID UPDATE: Clinical Guide for the Management of Critical Care for Adults with COVID-19

RAPID UPDATE: Clinical Guide for the Management of Critical Care for Adults with COVID-19

This RAPID UPDATE to the FICM/ICS "Clinical guide for the management of critical care for adults with COVID-19 during the Coronavirus pandemic" highlights five clinically urgent issues for practising clinicians caring for... read more

Management of Post-acute COVID-19 in Primary Care

Management of Post-acute COVID-19 in Primary Care

Post-acute COVID-19 ("long covid") seems to be a multisystem disease, sometimes occurring after a relatively mild acute illness. Clinical management requires a whole-patient perspective. This article, intended for... read more

Post-Hospital VTE in Patients with COVID-19

Post-Hospital VTE in Patients with COVID-19

The authors concluded that the rate of post-hospital venous thromboembolism (VTE) among patients with COVID-19 is low and that routine post-hospital prophylaxis is not necessary. Of the 1,877 hospital admissions with COVID-19... read more

Pulmonary Embolism in COVID-19 Patients in France

Pulmonary Embolism in COVID-19 Patients in France

Pulmonary embolism (PE) in the context of coronavirus disease 2019 (COVID-19) appears to be driven largely by inflammation and coagulopathy rather than by traditional risk factors for thromboembolism. Study results suggest... read more

Prophylaxis and Treatment of Venous Thromboembolic Disease in COVID-19

Prophylaxis and Treatment of Venous Thromboembolic Disease in COVID-19

Patients with COVID-19 appear to be at elevated risk for thrombotic complications, including venous thromboembolism (VTE).1 In addition to traditional risk factors for VTE, indirect effects of the severity of illness as well... read more

New NICE Guidelines on VTE Management

New NICE Guidelines on VTE Management

In the midst of everything that is going on with COVID-19 it is easy to see how important non coronavirus stuff can get overlooked. But we still need to keep our eyes open. After a 3 year process involving many meetings,... read more

Renal Function-Adjusted D-Dimer Levels in Critically Ill Patients With Suspected Thromboembolism

Renal Function-Adjusted D-Dimer Levels in Critically Ill Patients With Suspected Thromboembolism

D-Dimer cutoff levels adjusted for renal dysfunction appear feasible and safe assessing thromboembolic disease in critically ill patients. Furthermore, adjusted D-dimer cutoff levels seem reliable in patients with acute kidney... read more

Epidemiology of Clinically Relevant Bleeding in Critically Ill Adolescents

Epidemiology of Clinically Relevant Bleeding in Critically Ill Adolescents

Clinically Relevant Bleeding (CRB) is common in critically ill adolescents who are at high risk of venous thromboembolism (VTE). Admission after trauma or surgery can be used to stratify the risk of CRB in this population.... read more

Blood Grouping Identifies Patients at Risk for Developing Venous Thromboembolism

Blood Grouping Identifies Patients at Risk for Developing Venous Thromboembolism

Based on study of more than 28,000 TJA patients, presurgical ABO blood group testing looks like an inexpensive way to identify patents at increased risk for symptomatic postoperative VTE. Prophylaxis regimens can dramatically... read more

Parenteral Anticoagulation Not Associated with Reduced Risk of Ischemic Stroke Among Patients with Atrial Fibrillation During Sepsis

Parenteral Anticoagulation Not Associated with Reduced Risk of Ischemic Stroke Among Patients with Atrial Fibrillation During Sepsis

Among patients with Atrial Fibrillation (AF) during sepsis, parenteral anticoagulation was not associated with reduced risk of ischemic stroke and was associated with higher bleeding rates. Of 113,511 patients hospitalized... read more

Pulmonary Embolism Hospitalization, Readmission, and Mortality Rates in US Older Adults

Pulmonary Embolism Hospitalization, Readmission, and Mortality Rates in US Older Adults

Over the past 15 years, advances have occurred in the diagnosis and management of pulmonary embolism (PE).1 Computed tomographic pulmonary angiography (CTPA) is now the routine diagnostic test. The availability of risk... read more

Thromboelastography Predicts Thromboembolism in Critically Ill Coagulopathic Patients

Thromboelastography Predicts Thromboembolism in Critically Ill Coagulopathic Patients

Critically ill patients with deranged conventional coagulation tests are often perceived to have an increased bleeding risk. Whether anticoagulant prophylaxis for these patients should be withheld is contentious. This study... read more

Peripheral Vasopressors: The Myth and the Evidence

Peripheral Vasopressors: The Myth and the Evidence

You are working in a small, rural hospital staffed by one physician and one nurse. There are multiple sick patients, all of whom require your attention, but the sickest is probably the 62 year old female with pneumonia and... read more

Antithrombotic Therapy for Venous Thromboembolic Disease

Antithrombotic Therapy for Venous Thromboembolic Disease

This JAMA Clinical Guidelines Synopsis summarizes the American College of Chest Physicians' 2016 recommendations on antithrombotic therapy for venous thromboembolism (VTE). The estimated annual incidence of VTE, defined... read more

EHR-guided Strategy Reduces Postop VTE Events

EHR-guided Strategy Reduces Postop VTE Events

By incorporating algorithms into the electronic health record (EHR), UPMC was able to realize a "dramatic" 72% reduction in missed doses, from 4,331 missed doses in 2014 to 1,193 in 2015, Dr. Neal told attendees in a session... read more