Tag: trauma
Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe hemorrhage
Antifibrinolytics reduce death from bleeding in trauma and post-partum haemorrhage. We examined the effect of treatment delay on the effectiveness of antifibrinolytics. We obtained data for 40,138 patients from two randomised... read more
Shock Trauma to Study Body Cooling for Patients in Cardiac Arrest from Massive Bleeding
The R Adams Cowley Shock Trauma Center at the University of Maryland has opened a clinical trial to study whether rapidly cooling the body temperature of patients whose hearts stop due to massive blood loss will give surgeons... read more
Rapid Retriage of Critically Injured Trauma Patients
Critically injured patients presenting to nontrauma hospitals require timely transfer to trauma centers; however, the transfer process varies and differences in outcomes for patients from trauma centers are unknown. We evaluated... read more
Clinical Review: Paracetamol in fever in critically ill patients
Paracetamol is a synthetic, nonopioid, centrally acting analgesic and antipyretic drug. Its antipyretic effect occurres because it inhibits cyclooxygenase-3 and the prostaglandin synthesis.... read more
Maryland emergency doctors find new life-saving use in old machine
A little used machine designed to detox people who overdose on Tylenol and other medications found another use. Doctors at Shock Trauma used it to save a teenage gunshot victim and then a college football player and an amateur... read more
Variation in Monitoring and Treatment Policies for Intracranial Hypertension in TBI
Substantial variation was found regarding monitoring and treatment policies in patients with Traumatic Brain Injury (TBI) and intracranial hypertension. The results of this survey indicate a lack of consensus between European... read more
Individualizing Thresholds of Cerebral Perfusion Pressure Using Estimated Limits of Autoregulation
Individualized autoregulation-guided cerebral perfusion pressure management may be a plausible alternative to fixed cerebral perfusion pressure threshold management in severe traumatic brain injury patients. Prospective randomized... read more
Hyperventilation Therapy for Control of Post-Traumatic Intracranial Hypertension
During traumatic brain injury, intracranial hypertension (ICH) can become a life-threatening condition if it is not managed quickly and adequately. Physicians use therapeutic hyperventilation to reduce elevated intracranial... read more
Role of Preventability in Redefining Failure to Rescue Among Major Trauma Patients
Failure to rescue (FTR) is defined as death after a major complication and has been adopted as a measure of quality in surgical patients. Current definitions of FTR are limited because they do not account for the influence... read more
Why Point-of-Care Ultrasound Should be a Mainstay in EMS
A former firefighter/EMT turned medical student describes the functional components, diagnostic uses and roadblocks of using this imaging technology. From the first enormous and hefty ultrasound scanners, circa 1965, to today's... read more
Sepsis Prediction in Critically Ill Patients by Platelet Activation Markers on ICU Admission
Platelets have been involved in both immune surveillance and host defense against severe infection. To date, whether platelet phenotype or other hemostasis components could be associated with predisposition to sepsis in critical... read more
Should All Massively Transfused Patients Be Treated Equally?
Although balanced resuscitation has become integrated into massive transfusion practice, there is a paucity of evidence supporting the delivery of high ratios of plasma and platelet to RBCs in the nontrauma setting. This... read more
Focus on Brain Injury – The Staircase Approach
Focus on brain injury, staircase approach for the treatment of intracranial hypertension after TBI. The development of clinical protocols based on both laboratory and clinical data has underpinned the achievements of neurocritical... read more
Why a stay in the ICU can leave patients worse off
Almost 6 million patients land in an intensive care unit every year, and for many, it marks a turning point in their lives. A substantial number of patients leave the ICU with newly acquired problems, from dementia to nerve... read more
Neuro ICU Early Mobilization Protocol
Researchers in the U.S. have developed a multidisciplinary Neuro Early Mobilization Protocol for complex patients in the neuroscience intensive care unit (NSICU). Developing an evidence-based protocol with inter-professional... read more
Burnout Syndrome in Critical Care: A Call for Action
Burnout syndrome (BOS) is a work-related constellation of symptoms and signs that usually occurs in individuals with no history of psychological or psychiatric disorders. BOS is triggered by a discrepancy between the expectations... read more
Albumin Administration in Sepsis: The Case for and Against
Serum albumin is an essential plasma protein, with a variety of homeostatic and predictive roles in health and disease. Hypoalbuminaemia is common in critical illness. Human albumin solution has been administered clinically... read more
