Tag: treatment
Delay Within the 3-Hour Surviving Sepsis Campaign Guideline on Mortality for Patients With Severe Sepsis and Septic Shock
The guideline recommendations showed that shorter delays indicates better outcomes. There was no evidence that 3 hours is safe; even very short delays adversely impact outcomes. Findings demonstrated a new approach to incorporate... read more
Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction
Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction Among High-Risk Patients Undergoing Major Surgery. Among patients predominantly undergoing abdominal surgery who... read more
Antimicrobials for the Treatment of Drug-Resistant Acinetobacter Baumannii Pneumonia in Critically Ill Patients
This Bayesian network meta-analysis demonstrated the comparative effectiveness of fifteen antimicrobial treatments for drug-resistant A. baumannii pneumonia in critically ill patients. For survival benefit, SUL appears to... read more
Trends and Patterns of Antibiotic Consumption in China
The consumption of antibiotics is a major driver in the development of antimicrobial resistance. This study aims to identify the trends and patterns of the total antibiotic consumption in China’s tertiary hospitals from... read more
Cisatracurium Ups Some ARDS Outcomes Versus Vecuronium
Among patients with acute respiratory distress syndrome (ARDS), cisatracurium does not improve mortality versus vecuronium but is associated with improvements in other outcomes, according to a study published online in the... read more
Elevated BNP Levels in CFS Associated with Cardiac Dysfunction
This study confirms an association between reduced cardiac volumes and brain natriuretic peptide (BNP) in chronic fatigue syndrome (CFS). Lack of relationship between length of disease suggests that findings are not secondary... read more
Clinicians’ Expectations of the Benefits and Harms of Treatments, Screening, and Tests
Clinicians rarely had accurate expectations of benefits or harms, with inaccuracies in both directions. However, clinicians more often underestimated rather than overestimated harms and overestimated rather than underestimated... read more
Effect of Antibiotic Prophylaxis on Surgical Site Infections Following Removal of Orthopedic Implants
In this randomized clinical trial that included 470 patients who were undergoing surgery for removal of orthopedic implants used for treatment of below-the-knee fractures, surgical site infection occurred in 12.9% of patients... read more
The Iatrogenic Potential of the Physician’s Words
Some of the information that physicians convey to their patients can inadvertently amplify patients' symptoms and become a source of heightened somatic distress, an effect that must be understood by physicians to ensure optimal... read more
A Research Agenda for Communication Between Health Care Professionals and Patients Living With Serious Illness
Poor communication by health care professionals contributes to physical and psychological suffering in patients living with serious illness. Patients may not fully understand their illness, prognosis, and treatment options... read more
Endoscopic Treatment versus Shunting for Hydrocephalus
In sub-Saharan Africa, a large number of infants are affected by hydrocephalus that develops after neonatal ventriculitis and is often associated with poor developmental outcomes. New research findings are summarized in a... read more
Dietitians in Critical Care
Patients in the critical care setting are at risk of malnutrition. The provision of nutrition support (enteral or parenteral) to critically ill patients is vital, but achieving the optimum quantity and balance is a contentious... read more
Inpatient antiviral treatment reduces ICU admissions among influenza patients
Administering inpatient antiviral influenza treatment may reduce admissions to the ICU among adults hospitalized with flu, according to a study presented at ID Week 2017, an infectious diseases meeting. While interventions... read more
Is Simvastatin the Miracle Drug We Think It Is?
Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation. This well designed and conducted trial demonstrates that there is... read more
Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis
The post-thrombotic syndrome frequently develops in patients with proximal deep-vein thrombosis despite treatment with anticoagulant therapy. Pharmacomechanical catheter-directed thrombolysis (hereafter "pharmacomechanical... read more
Music and Medicine: Something Important
Every week or 2 when I don’t have a daytime shift, I set up my iPad and play piano for an hour or so. Nothing depressing or too complicated—feel-good music from the 1930s to the latest by John Legend or Coldplay. The... read more
Effects of Physical Activity on Poststroke Cognitive Function
Despite the social, health, and economic burdens associated with cognitive impairment poststroke, there is considerable uncertainty about the types of interventions that might preserve or restore cognitive abilities. The... read more
Increase in antibiotic-resistant bacteria hinders treatment of kidney infections
Researchers use hospital emergency room data from around the country to document emergence of E. coli strain that fights medication. They recommend development of new antibiotics and treatment guidelines.... read more
Pseudomonas aeruginosa exoproducts determine antibiotic efficacy against Staphylococcus aureus
Chronic coinfections of Staphylococcus aureus and Pseudomonas aeruginosa frequently fail to respond to antibiotic treatment, leading to significant patient morbidity and mortality. Currently, the impact of interspecies interaction... read more
The Role of Hospital Pharmacist in the Screening, Prevention and Treatment of Delirium
An interdisciplinary approach is fundamental for effective prevention and treatment of delirium. Pharmacists could play a role in identifying and resolving medication-related delirium. However, little is known about their... read more
Tissue Edema, Fluid Balance, and Patient Outcomes in Severe Sepsis
Severe sepsis and septic shock remain among the deadliest diseases managed in the intensive care unit. Fluid resuscitation has been a mainstay of early treatment, but the deleterious effects of excessive fluid administration... read more
