New NICE Guidelines on VTE Management

In the midst of everything that is going on with COVID-19 it is easy to see how important non coronavirus stuff can get overlooked. But we still need to keep our eyes open. After a 3 year process involving many meetings,... read more

New NICE Guidelines on VTE Management

COVID-19: Thrombosis and Anticoagulation

Early reports have shown that COVID-19 is most likely causing a hypercoagulable state, however the prevalence of acute VTE and exactly how to treat it is an evolving area. Limited data suggest pulmonary microvascular thrombosis... read more

COVID-19: Thrombosis and Anticoagulation

Epidemiology of Clinically Relevant Bleeding in Critically Ill Adolescents

Clinically Relevant Bleeding (CRB) is common in critically ill adolescents who are at high risk of venous thromboembolism (VTE). Admission after trauma or surgery can be used to stratify the risk of CRB in this population.... read more

Epidemiology of Clinically Relevant Bleeding in Critically Ill Adolescents

Blood Grouping Identifies Patients at Risk for Developing Venous Thromboembolism

Based on study of more than 28,000 TJA patients, presurgical ABO blood group testing looks like an inexpensive way to identify patents at increased risk for symptomatic postoperative VTE. Prophylaxis regimens can dramatically... read more

Blood Grouping Identifies Patients at Risk for Developing Venous Thromboembolism

Antithrombotic Therapy for Venous Thromboembolic Disease

This JAMA Clinical Guidelines Synopsis summarizes the American College of Chest Physicians' 2016 recommendations on antithrombotic therapy for venous thromboembolism (VTE). The estimated annual incidence of VTE, defined... read more

Antithrombotic Therapy for Venous Thromboembolic Disease

EHR-guided Strategy Reduces Postop VTE Events

By incorporating algorithms into the electronic health record (EHR), UPMC was able to realize a "dramatic" 72% reduction in missed doses, from 4,331 missed doses in 2014 to 1,193 in 2015, Dr. Neal told attendees in a session... read more

EHR-guided Strategy Reduces Postop VTE Events

Association of Inferior Vena Cava Filter Placement for Venous Thromboembolic Disease and a Contraindication to Anticoagulation With 30-Day Mortality

After adjustment for immortal time bias, Inferior Vena Cava (IVC) filter placement was associated with increased 30-day mortality in patients with venous thromboembolic disease (VTE) and a contraindication to anticoagulation.... read more

Association of Inferior Vena Cava Filter Placement for Venous Thromboembolic Disease and a Contraindication to Anticoagulation With 30-Day Mortality

Lack of association between airflow limitation and recurrence of venous thromboembolism among cancer patients with pulmonary embolism

The presence of airflow limitation did not increase the risk of VTE recurrence in cancer patients with PE. Prospective studies are needed to validate this finding. Among 401 cancer patients with newly diagnosed PE, spirometry-based... read more

Lack of association between airflow limitation and recurrence of venous thromboembolism among cancer patients with pulmonary embolism

Discharge Instructions for VTE: A Comprehensive Approach to Medication Management

Discharge instructions for VTE have typically included medication management recommendations related to the use of warfarin. In recent years, however, a growing number of alternatives to warfarin, such as direct oral anticoagulants... read more

Discharge Instructions for VTE: A Comprehensive Approach to Medication Management

Risk of Venous Thromboembolism in Patients by Albuminuria and Estimated GFR

Albuminuria increases the risk for VTE markedly in patients with normal eGFRs compared with those with lower eGFRs. 15,180 (2.2%) VTE events occurred during the study period. Both albuminuria and eGFR were independently associated... read more

Risk of Venous Thromboembolism in Patients by Albuminuria and Estimated GFR

The YEARS Study – Simplified Diagnostic Management of PE

The clinical diagnosis of pulmonary embolism (PE) can be challenging given its variable presentation, requiring dependence on objective testing. Decision instruments such as PERC and the Wells' score help stratify patients... read more

The YEARS Study – Simplified Diagnostic Management of PE

FDA approves betrixaban for VTE prophylaxis

Betrixaban, a factor Xa inhibitor, has been approved for the prophylaxis of venous thromboembolism (VTE) in at-risk adult patients hospitalized with an acute illness, according to an announcement from the Food and Drug Administration.... read more

FDA approves betrixaban for VTE prophylaxis

Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery

Few head-to-head treatment comparisons have sufficient evidence. Most studies evaluated low molecular weight heparin (LMWH), not low-risk interventions (such as aspirin and mechanical devices); most reported on total deep... read more

Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery

Principles learned from a successful VTE improvement program

Principles learned from a successful improvement program can increase compliance and reduce hospital acquired VTEs (HA-VTEs) across multiple institutions. Can a single institution’s VTE prophylaxis program be scaled to... read more

Principles learned from a successful VTE improvement program

Thromboprophylaxis after Knee Arthroscopy and Lower-Leg Casting

The results of our trials showed that prophylaxis with low-molecular-weight heparin for the 8 days after knee arthroscopy or during the full period of immobilization due to casting was not effective for the prevention of... read more

Thromboprophylaxis after Knee Arthroscopy and Lower-Leg Casting

GCA independently raises risk for VTE

The risk of venous thromboembolism (VTE) increases markedly shortly before the diagnosis of giant cell arteritis (GCA) regardless of glucocorticoid exposure, peaks at the time of diagnosis, and then progressively declines,... read more

GCA independently raises risk for VTE

Testosterone VTE Risk; Novel Clot Buster Flops Again; Saturated Fat Culpability

The venous thromboembolism (VTE) risk warned about with testosterone treatment appears to be transient, peaking within 6 months after starting and then gradually declining.... read more

Testosterone VTE Risk; Novel Clot Buster Flops Again; Saturated Fat Culpability

New Clinical Resources From American Association Of Critical-Care Nurses Address Delirium, CAUTI And VTE

Updated AACN Practice Alerts offer latest evidence-based practice related to delirium, catheter-associated urinary tract infections and venous thromboembolism.... read more

New Clinical Resources From American Association Of Critical-Care Nurses Address Delirium, CAUTI And VTE