Researchers at the Royal College of Surgeons in Ireland (RCSI) have tested a compound called cilengitide in a preclinical trial. The drug goes by the brand name InnovoSep. Researchers discover the drug has the potential to... read more

This easy-to-read book uses the popular and trusted Secrets Series question-and-answer format to cover all areas of critical care medicine, focusing on the practical, “in-the-trenches” know-how you need to succeed... read more

In patients presenting to the emergency department with recent-onset, symptomatic atrial fibrillation, a wait-and-see approach was noninferior to early cardioversion in achieving a return to sinus rhythm at 4 weeks. The presence... read more

ICU patients have more chronic conditions during the year before ICU admission compared with a population-based control group and a five times higher odds on developing one or more new chronic conditions compared with the... read more

The first step-by-step manual for any nurse in any specialty to stop nurse burnout, build a more ideal career and a more balanced life. Chart your course from Nurse Burnout to Your Ideal Career using this first comprehensive... read more

Extravascular lung water (EVLW) remains a useful guide for monitoring pulmonary edema (PO) and vascular permeability in sepsis, acute respiratory distress syndrome (ARDS), and heart failure. In addition, EVLW has a prognostic... read more

As many ED practitioners are aware, food allergies are common in the first 2 years of life, with a prevalence cited between 1-10% of the population. Most food allergies are IgE-mediated hypersensitivity reactions. Food protein-induced... read more

The PICU Handbook is a unique, portable compilation of the information essential for residents and fellows to successfully navigate the modern Level 1 and Level 2 pediatric intensive care unit (PICU). Enhanced by numerous... read more

The worldwide use of extracorporeal lung/life support is increasing in severe lung failure (veno-venous extracorporeal membrane oxygenation, vvECMO) or in cardiac arrest/severe circulatory failure (veno-arterial ECMO, vaECMO).... read more

When the number of patients who require intensive care is greater than the number of beds available, intensive care unit (ICU) entry flow is obstructed. This phenomenon has been associated with higher mortality rates in patients... read more

This is the premier evidence-based textbook in critical care medicine. The Third Edition features updated and revised chapters, numerous new references, streamlined content, and new chapters on key topics such as the new... read more

Post-ICU hospital-based rehabilitation, including increased physical and nutritional therapy plus information provision, did not improve physical recovery or HRQOL, but improved patient satisfaction with many aspects of recovery.... read more

Acute kidney injury (AKI) is a common complication of major surgery. However, acute kidney injury occurring within the first 48 hours after surgery (early acute kidney injury) and therefore likely related to the surgery itself... read more

Transfusion of red blood cells is an everyday practice in critical care with the primary aim of restoring adequate tissue oxygenation. However, blood transfusion may also be harmful and costly, therefore a so called restrictive... read more

Critical Care Pearls for medical professionals involved in taking care of critically ill patients. An excellent resource for board review written by Dr. Iqbal Ratnani and Dr. Salim Surani. Dr. Iqbal Ratnani, MD, FCCP, FCCM... read more

So far, we’ve only been looking at metrics that are really big and important. This is certainly a good place to start. To move beyond this, I’d like to introduce the concept of Outcome vs Process Metrics. Outcome... read more

Inspired by underwater invertebrates such as the jelly fish, Assistant Professor Benjamin Tee and his team from NUS Materials Science and Engineering, in collaboration with researchers from Tsinghua University, China and... read more

Currently, the majority of individuals who undergo transcather aortic valve replacement (TAVR), a minimally invasive alternative to open-heart surgery—are elderly or subject to compounding complications such as kidney disease.... read more

In the near future, space programs will shift their focus toward long‐duration interplanetary missions, in particular to the Moon and Mars. These exploration missions will be associated with an increased risk of acute medical... read more

This is the first comprehensive study guide covering all aspects of pediatric critical care medicine. It fills a void that exists in learning resources currently available to pediatric critical care practitioners. The major... read more