Tocilizumab vs. IVIG in Patients with Severe COVID-19 Pneumonia

Severe COVID-19 patients who received IVIG in the early phase of the disease did not show better clinical outcomes in terms of mortality, hospitalization time and intensive care unit admission compared to those who received... read more

Tags: bradycardia, COVID-19, dexamethasone, ICU, infusion, mechanical ventilation, oxygen, pneumonia, study, treatment,

Clinical Respiratory Anatomy and Physiology in the ICU: Anatomophysiopathology and gasometry of patients on invasive mechanical ventilation

Breathing is a physiological process that is fundamental to life. The respiratory system can be likened to a vital pump allowing the exchange of gases between the cells of an organism and the external environment. A number... read more

Tags: book, education, ICU, mechanical ventilation, oxygenation,

Anesthesia Role in Sedation and Weaning From Mechanical Ventilation

This systematic review highlights the advantages of anesthetic sedation strategies, particularly the use of dexmedetomidine, methadone, or sequential sedation protocols, in improving weaning outcomes, enhancing sedation quality,... read more

Tags: delirium, dexamethasone, dexmedetomidine, ICU, mechanical ventilation, sedation, study, weaning,

Sepsis Management: PIRO and MODS

This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent... read more

Tags: antibiotics, book, infection, MODS, sepsis, treatment,

Weaning Failure Prediction Using Electrocardiographic Time-frequency Analysis and Respiration Flow Signals

Weaning patients from mechanical ventilation (MV) is a crucial process that requires meticulous assessment of their ability to breathe independently without ventilatory assistance. Spontaneous breathing test (SBT) is a widely... read more

Tags: ARDS, extubation, hypoxemia, ICU, mechanical ventilation, SBT, ventilation, weaning,

Analgosedation Practice During Noninvasive Respiratory Supports

Sedation is frequently used in patients with acute respiratory failure (ARF) undergoing Noninvasive Respiratory Supports (NRSs). Current analgesic practices are becoming more standardized, with analgosedation strategies increasingly... read more

Tags: airway, ARF, COVID-19, delirium, ICU, intubation, mechanical ventilation, NIV, pain, sedation, ventilation,

Management of Chest Trauma: A Practical Guide

75% of patients who die from trauma have injuries to the chest. The care of the chest trauma patient can be incredibly complex, require multiple specialty and sub-specialty services, and may require interventions available... read more

Tags: anesthesia, book, education, ICU, monitoring, pain, resuscitation, trauma, ventilation,

Serum MANF vs. Severity and Prognosis in Community-acquired Pneumonia Patients

This evidence demonstrated that serum mesencephalic astrocyte-derived neurotrophic factor (MANF) is positively associated with scoring criteria and poor prognosis in community-acquired pneumonia (CAP) patients. Serum MANF... read more

Tags: biomarkers, CAP, COVID-19, diagnosis, ICU, pneumonia, prognostics, study, VAP,

Baricitinib Use in Children with Severe COVID-19 Infection

Baricitinib appears safe for both immunocompetent and immunocompromised children hospitalized for severe COVID-19. Most adverse events did not inhibit therapy administration, and there were no deaths following the initiation... read more

Tags: COVID-19, DVT, ICU, pediatrics, pulmonary embolism, research, therapy, treatment,

Improving Critical Care Survivorship: A Guide to Prevention, Recovery, and Reintegration

This book, just published, provides a comprehensive overview of improving critical care survivorship. Comprised of four sections, the text presents interventions that can be used to improve patient outcomes and reduce the... read more

Tags: book, education, ICU, recovery, rehabilitation,

Wireless Wearable Doppler Ultrasound: Monitoring Trauma Patients

This study demonstrated the feasibility of placing the wireless, wearable Doppler ultrasound on severely injured trauma patients admitted to the trauma bay of a busy level 1 trauma center. The device reliably captured the... read more

Tags: hemorrhage, ICU, monitoring, resuscitation, trauma, ultrasound,

Femoral Head Osteonecrosis in Post-COVID-19 Patients

This study provides an insight into the relationship between COVID-19-related factors and the development of osteonecrosis of the femoral head (ONFH), emphasizing the critical role of cumulative steroid dose as the primary... read more

Tags: corticosteroids, COVID-19, infection, steroids, study, therapy, treatment,

Ventilator Management: A Pre-Hospital Perspective

The goal of this book is to provide the most up to date information on mechanical ventilation based on current research, evidence based practice and my experiences as a flight paramedic and educator. A comprehensive look... read more

Tags: book, education, mechanical ventilation, oxygenation, ventilation, ventilator,

Holy Water Not so Holy: Potential Source of Elizabethkingia Pneumonia and Bacteremia in an Immunocompromised Host

This case report highlights that E. anophelis may indeed cause significant infection and should not be considered a contaminant especially in immunosuppressed individuals. The organism originates from water sources and may... read more

Tags: antibiotics, bacteremia, diagnosis, dialysis, hydrocortisone, hyperkalemia, ICU, infection, pneumonia, VAP,

Clinical Characteristics and Survival Outcomes of Invasive Pulmonary Aspergillosis Patients

Invasive pulmonary aspergillosis (IPA) is a severe infectious disease caused by Aspergillus spp. It is associated with high mortality, particularly in immunocompromised patients, as well as in those with COVID-19 pneumonia... read more

Tags: biomarkers, COVID-19, diagnosis, ICU, infection, pneumonia,

50 Landmark Papers Every Intensivist Should Know

This book identifies the key scientific articles in the field of Intensive Care and explains why these papers are important in contemporary clinical management. Identifying those influential contributors who have shaped the... read more

Tags: book, education, ICU,

Levosimendan Role in ECMO for Refractory Cardiac Arrest

Levosimendan use in extracorporeal cardiopulmonary resuscitation (ECPR) did not improve survival. Neurological outcome could be representative of the short- and long-term outcomes. Future well-designed randomized trials are... read more

Tags: cannulation, cardiac arrest, cardiogenic shock, CPR, ECMO, ECPR, ICU, resuscitation, study,

Aminoglycosides Impact on Survival Rate and Renal Outcomes in Patients with Urosepsis

The addition of aminoglycosides to beta-lactam therapy in critically ill patients with urosepsis did not significantly improve 30-day survival. Furthermore, aminoglycosides were not associated with worse renal outcomes. These... read more

Tags: AKI, antibiotics, ICU, infection, sepsis, septic shock, therapy,

Dexmedetomidine Use for Palliative Sedation in Non-ICU Settings

Dexmedetomidine is a promising adjunct to be considered for palliative sedation when managing end-of-life symptoms such as refractory pain, anxiety, or delirium. This medication should be considered a reasonable alternative... read more

Tags: anxiety, delirium, dexmedetomidine, ICU, pain, palliative care, sedation,

Cardiac Intensive Care

Using a multidisciplinary, team-oriented approach, this unique title expertly covers all the latest approaches to the assessment, diagnosis, and treatment of patients with critical cardiac illness. Led by Dr David L. Brown,... read more

Tags: book, education, guidelines, hypertension, mechanical ventilation, resuscitation,

Ventilator-associated Pneumonia Pathogenesis: Old and New Mechanisms

Ventilator-associated pneumonia (VAP), defined as a lung infection that occurs in patients after 48 hours on mechanical ventilation, is among the most frequently found nosocomial infections in intensive care units around... read more

Tags: antibiotics, ICU, infection, mechanical ventilation, pneumonia, VAP,

Fever Management with or without a Temperature Control Device After OHCA and Resuscitation

the TEMP‐CARE trial will advance our understanding of post‐cardiac arrest care fever management strategies. With a large sample size and a broad patient population, the results of this trial will inform clinical practice... read more

Tags: anticoagulants, arrhythmia, cardiac arrest, guidelines, hemorrhage, ICU, OHCA, resuscitation, sedation, study, trial,

Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill

This book provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence...

Pulmonary Hypertension: Basic Science to Clinical Medicine

This book provides the framework for a singular reference in the field of pulmonary hypertension. Pulmonary vascular disease is a complex and heterogeneous condition characterized by remodeling of distal pulmonary arterioles...