Quickly and accurately diagnose and treat the critically ill patient with guidance from the field’s definitive text. Considered the field’s definitive text, Principles of Critical Care offers... read more

Cerebral auto-regulation was altered in half of the patients with sepsis and was associated with the development of SABD. These findings support the concept that cerebral hypoxia could contribute to the... read more

The predictive models evaluated in this study demonstrated moderate to good discriminative ability to predict ICU patients’ risk of developing delirium. Models calculated at 24-hours post-ICU admission... read more

With a focus on evidence-based, state-of-the-art information throughout, the eighth edition of Irwin and Rippe’s Intensive Care Medicine offers authoritative guidance to the wide variety of specialty... read more

Hemoglobin is important for cerebral oxygenation and strategies to minimize anemia should be undertaken. Although higher hemoglobin levels are associated with less cerebral ischemia and better clinical... read more

In this cohort, the major risk factors for septicemia death were similar to those for other causes of death, there was approximately a 2-fold Black-White disparity in septicemia deaths, and the strongest... read more

This is the first comprehensive study guide covering all aspects of pediatric critical care medicine. It fills a void that exists in learning resources currently available to pediatric critical care practitioners.... read more

Convulsive status epilepticus (CSE) is the most common life-threatening childhood neurological emergency. Despite this, there is a lack of high quality evidence supporting medication use after first line... read more

Critical care transport of prone acute respiratory distress syndrome (ARDS) patients is a feasible and cost-effective intervention that will help prevent treatment delays and interruptions. A nonphysician... read more

An immediate classic, this groundbreaking text is based on the premise that neurointensivists must be trained to handle not only the brain, but the entire body. The NeuroICU Book, Second Edition does not... read more

Our study confirmed an association between higher driving pressure and higher mortality in mechanically ventilated patients with acute respiratory distress syndrome (ARDS). These findings suggest a possible... read more

This complex randomized, controlled trial failed to demonstrate that early extubation to non-invasive ventilation reduced the total time of mechanical ventilation. I will continue to extubate early and... read more

In the study cohort, ICU admission pectoralis muscle area (PMA) was associated with survival during and following critical illness; it was unable to predict regaining an independent lifestyle following... read more

The term “intensive care unit” (ICU) was originally meant to refer to the intensity of the resources allocated to patient care. Today, however, ICU refers more to the intensity of the interventions... read more

Current evidence does not support the use of non-pharmacological interventions in reducing incidence and duration of delirium in critically ill patients. Future research should consider well-designed and... read more

FMT has become an attractive option to mitigate multiple organ dysfunction in the ICU. This article discusses the physiology, rationale, early experience, and expectations for such therapy in the critically... read more

The recovery programme intended for intensive care survivors did not have an effect on the relatives. Future recovery programmes should be targeted to help both patient and family, and future research... read more

Lower RN staffing and higher levels of admissions per RN are associated with increased risk of death during an admission to hospital. These findings highlight the possible consequences of reduced nurse... read more

A large proportion of Japanese patients on mechanical ventilation (MV) were treated in non-ICU settings. Analysis of administrative data indicated preliminary that hospital mortality rates in these patients... read more

Survivors of critical illness frequently experience poor physical outcomes, including persistent impairments in muscle strength, exercise capacity and physical function. In this article, we review these... read more