Predicting NIV Failure in Hypoxemic Patients

Non-invasive ventilation (NIV) is applied worldwide to patients with hypoxemic respiratory failure. It is often applied as an attempt to avoid invasive mechanical ventilation. However, the application of NIV is often... read more

Trying Not to Intubate Early & Why ARDSnet may be the Wrong Ventilator Paradigm

Many of us have been working under the paradigm that COVID-19 PNA eventually develops into ARDS in the sickest patients. It appears to me that these patients don’t fit into this paradigm. Many have normal to high compliance... read more

Management of COVID-19 Respiratory Distress

Acute respiratory distress syndrome (ARDS) can originate from either the gas or vascular side of the alveolus. Although the portal for coronavirus disease 2019 (COVID-19) is inhalational, and alveolar infiltrates are commonly... read more

For the First Time in My Life, Going to Work Scares Me

And coming home scares me even more. Two New York ER doctors log their days, one month into the city's coronavirus crisis. Having trained in an intense ER residency, I'm used to seeing all sorts of critical situations.... read more

Here’s a Lifesaving COVID-19 Test That Costs Almost Nothing

The New York Times ran a fascinating op-ed on Monday, and I’m surprised that it hasn’t gotten more attention. Here’s the nickel summary: a hotshot ER doctor volunteered to spend time at Bellevue Hospital in Manhattan... read more

Characteristics of Hospitalized Adults With COVID-19 in California

Coronavirus disease 2019 (COVID-19) has resulted in increased hospital and intensive care unit (ICU) use. In the United States, few reports have characterized patients treated outside of the ICU. Northern California was... read more

Patient Self-proning with HFNC Improves Oxygenation in COVID-19 Pneumonia

A high-flow nasal cannula (HFNC) is commonly used in the management of hypoxic respiratory failure, and is associated with more ventilator-free days and lower mortality compared with standard oxygen therapy or non-invasive... read more

Constantly Shifting Strategies for COVID-19

We are all learning as we go, but we are seeing more than 200 COVID-19 patients every day in our emergency department in Queens, NY, and this is what we are doing to evaluate and treat patients, keep everyone safe, and boost... read more

PPE for Both Anesthesiologists and Other Airway Managers

Healthcare providers are facing a coronavirus disease pandemic. This pandemic may last for many months, stressing the Canadian healthcare system in a way that has not previously been seen. Keeping healthcare providers safe,... read more

Use of High Flow Oxygen Therapy Devices During the COVID-19 Epidemic

Medicines & Healthcare Products Regulatory Agency (MHRA) released a Central Alerting System (CAS) notice about the risk of a sudden pressure drop in oxygen supply pipes if demand through multiple wall outlets exceeds the... read more

Canopy Protects Healthcare Workers From COVID-19 Infection During Ventilation

Researchers have designed a cost-effective, constant flow plastic canopy system that can help to protect healthcare workers who are at risk of airborne coronavirus infection while delivering non-invasive ventilation or oxygen... read more

Expert Panel Develops NIH Treatment Guidelines for COVID-19

A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COVID-19). These guidelines, intended for healthcare providers, are based on published and preliminary... read more

COVID-19 and Critical Care

In this podcast, we talk about the clinical journey of a COVID-19 patient and some insights from the critical care unit. There are some concepts here that we probably don't do full justice to in the time we had, so here are... read more

Kill as Few Patients as Possible

This oft-quoted all-time favorite of the medical community will gladden - and strengthen - the hearts of patients, doctors, and anyone entering medical study, internship, or practice. With unassailable logic and rapier... read more

Kill as Few Patients as Possible

Crisis Management in Anesthesiology

The fully updated Crisis Management in Anesthesiology continues to provide updated insights on the latest theories, principles, and practices in anesthesiology. From anesthesiologists and nurse anesthetists to emergency physicians... read more

Crisis Management in Anesthesiology

How I Manage Drainage Insufficiency on ECMO

As the use of extracorporeal membrane oxygenation (ECMO) expands, a systematic approach to the management of complex technical issues, such as drainage insufficiency, is essential to improving patient outcomes. Due to... read more

First Case of COVID-19 Complicated With Fulminant Myocarditis

COVID-19 patients may develop severe cardiac complications such as myocarditis and heart failure. This is the first report of COVID-19 complicated with fulminant myocarditis. The mechanism of cardiac pathology caused by COVID-19... read more

Missing Microbes: How the Overuse of Antibiotics Is Fueling Our Modern Plagues

Renowned microbiologist Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for... read more

Missing Microbes: How the Overuse of Antibiotics Is Fueling Our Modern Plagues

Keeping the Coronavirus from Infecting Health-Care Workers

The message is getting out: #StayHome. In this early phase of the coronavirus pandemic, with undetected cases accelerating transmission even as testing ramps up, that is critical. But there are many people whom the country... read more

COVID-19 Pneumonia: ARDS or Not?

Even though it can meet the ARDS Berlin definition, the COVID-19 pneumonia is a specific disease with peculiar phenotypes. Its main characteristic is the dissociation between the severity of the hypoxemia and the maintenance... read more

A Novel ECG-biomarker for Cardiac Arrest During Hypothermia

Treatment of arrhythmias evoked by accidental or therapeutic hypothermia and rewarming remains challenging. We aim to find an ECG-biomarker that can predict ventricular arrhythmias at temperatures occurring in therapeutic... read more

Understanding Happy Hypoxemia Physiology During COVID-19

Happy hypoxemia is severe hypoxemia (poorly responsive to supplemental oxygen) without dyspnea. This isn't anything especially new – we have occasionally seen this since time immemorial. However, COVID is causing us to... read more