Together: The Healing Power of Human Connection in a Sometimes Lonely World

Together: The Healing Power of Human Connection in a Sometimes Lonely World

The book we need NOW to avoid a social recession, Murthy’s prescient message is about the importance of human connection, the hidden impact of loneliness on our health, and the social power of community. Humans are social... read more

The Case for Routine Screening for COVID-19 Before Surgery

The Case for Routine Screening for COVID-19 Before Surgery

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused more than 5 million cases of coronavirus disease (COVID-19) worldwide and 345,000 deaths as of 25 May 2020. Based on accumulating international experience... read more

Perhaps something isn’t always better than nothing

Perhaps something isn’t always better than nothing

It is not unreasonable to say the COVID-19 pandemic caught most of us by surprise. We did not know how infectious the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) virus leading to COVID-19 disease was, nor... read more

From despair to hope: advanced therapy gives a lifeline to the sickest COVID-19 patients

From despair to hope: advanced therapy gives a lifeline to the sickest COVID-19 patients

More than two months later, that piece of paper still lies on her coffee table with four letters on it: "E-C-M-O." Irena Veronese had never heard that acronym before, but when it was first mentioned to her, it meant moving... read more

Effect of Dexamethasone in Hospitalized Patients with COVID-19

Effect of Dexamethasone in Hospitalized Patients with COVID-19

Although the paper is not even officially published yet, everyone has already heard the results. We have our first treatment that appears to reduce mortality in COVID-19 patients. For a week or so, we only had press release,... read more

Hydrocortisone Prevents Immunosuppression by interleukin-10+ Natural Killer Cells After Trauma-Hemorrhage

Hydrocortisone Prevents Immunosuppression by interleukin-10+ Natural Killer Cells After Trauma-Hemorrhage

These data demonstrate that trauma-induced immunosuppression is characterized by an interleukin-10-dependent elimination of dendritic cell by natural killer cells and that hydrocortisone improves outcome by limiting this... read more

Procedural Sedation in the COVID-19 Era

Procedural Sedation in the COVID-19 Era

Resuming procedural sedation services for elective procedures during the COVID-19 pandemic requires unique considerations to ensure safety for patients and providers. Guidelines for resuming these procedures, including timing,... read more

What’s the Difference Between COVID-19 Tests?

The COVID-19 pandemic, tests, treatments, and outlook, continue to be front and center in the news, along with other urgent issues taking place across the country. Viral sepsis is the number one complication related to... read more

Exhaled Air Dispersion During Bag-mask Ventilation and Sputum Suctioning

Exhaled Air Dispersion During Bag-mask Ventilation and Sputum Suctioning

Mask ventilation and coughing during oro-tracheal suctioning produce aerosols that enhance nosocomial transmission of respiratory infections. We examined the extent of exhaled air dispersion from a human-patient-simulator... read more

The Relevance of Thromboinflammation and Endothelial Dysfunction in COVID-19 Patients

The Relevance of Thromboinflammation and Endothelial Dysfunction in COVID-19 Patients

The relevance of thromboinflammation and endothelial dysfunction in COVID-19 patients. Microvascular derangement is a key mechanism of multiple organ dysfunction and therapeutic strategies other than heparin, aimed at preserving... read more

The COVID-19 Coronavirus is Changing

The COVID-19 Coronavirus is Changing

When a handful of doctors in northern Italy recently claimed that the virus that causes COVID-19 appears to be losing steam, that it no longer seems to be the same “biological bomb” it was when the pandemic first hit,... read more

Biomarkers of Sepsis: Time for a Reappraisal

Biomarkers of Sepsis: Time for a Reappraisal

The precise roles of most biomarkers in the management of septic patients have not been well defined, and of the many biomarkers that have been studied, only a few have been evaluated in large or repeated studies. As... read more

Prevention, Detection and Management of VTE in COVID-19 Patients

Prevention, Detection and Management of VTE in COVID-19 Patients

Several studies have demonstrated coagulation changes in patients with COVID-19, especially in those with severe disease, and this is associated with a worse prognosis. Emerging data, alongside recent clinical experience,... read more

The use of continuous perineural catheters and other practices to optimize regional anesthesia in COVID-19 patients

The use of continuous perineural catheters and other practices to optimize regional anesthesia in COVID-19 patients

As anesthesiologists, we are on the front line of the fight against coronavirus disease (COVID-19), whether in the intensive care unit, operating room, or elsewhere in the hospital. Given the highly contagious nature of the... read more