When ICU Delirium Leads To Symptoms Of Dementia After Discharge

Doctors have gradually come to realize that people who survive a serious brush with death in the intensive care unit are likely to develop potentially serious problems with their memory and thinking processes. This dementia,... read more

Comparison between procalcitonin and C-reactive protein to predict blood culture results in ICU patients

Biomarkers represent an essential tool for identification of patients developing infection and to determine their clinical severity. Procalcitonin (PCT) levels appeared to be correlated with the development of severe bacterial... read more

Meet the trillions of viruses that make up your virome

If you think you don’t have viruses, think again. It may be hard to fathom, but the human body is occupied by large collections of microorganisms, commonly referred to as our microbiome, that have evolved with us since... read more

Navigating Medical Emergencies – An interactive guide to patient management

This free eBook presents emergent clinical situations and the core tasks required of healthcare professionals needing to recognize, navigate and safely manage them. It's really about how to perform the ABCs while protecting... read more

The A.S.P.E.N. Pediatric Nutrition Support Core Curriculum

A valuable resource for certification preparation and the daily nutrition care of pediatric patients focusing on the importance of nutrition to the growth and development of children. Written with an interdisciplinary evidence-based... read more

The A.S.P.E.N. Pediatric Nutrition Support Core Curriculum

ESPEN Guideline on Clinical Nutrition in the ICU

Following the new ESPEN Standard Operating Procedures, the previous guidelines to provide best medical nutritional therapy to critically ill patients have been updated. These guidelines define who are the patients at risk,... read more

ICU Care Improved with Conflict Management Education

Stressful by nature, the intensive care unit (ICU) inevitably faces conflicts due to immediate and cohesive action from physicians, nurses, respiratory therapists, and advanced practitioners. In an effort to help improve... read more

Alcohol Withdrawal: One Order to Sedate Them All

This is a retrospective cohort study describing 86 admissions to the ICU for alcohol withdrawal between 2011-2015. 86% were treated with benzodiazepines before ICU admission, usually on the general ward. The average dose... read more

Triiodothyronine Replacement in Critically Ill Adults with Non-thyroidal Illness Syndrome

This study suggests that with triiodothyronine (T3) supplementation there was evidence of serum free T3 normalization without evidence of associated harms. A definitive trial is needed to evaluate clinical effectiveness.... read more

Should ICU clinicians follow patients after ICU discharge? No

Post-intensive care syndrome (PICS) describes new or worsening impairments of physical, cognitive or mental health resulting from an episode of critical illness and its treatment and lasting after discharge... read more

Should ICU clinicians follow patients after ICU discharge? Yes

The trajectory of recovery from critical illness is often portrayed as a continuum. At one extremity lies an unstable patient dependent on life-sustaining treatments in the intensive care unit. At the... read more

Early PREdiction of Sepsis Using Leukocyte Surface Biomarkers

From a large panel of leukocyte biomarkers, immunosuppression biomarkers were associated with subsequent sepsis in ED patients with suspected acute infection. Between January 2014 and February 2016, we recruited 272, 59 and... read more

Organ and Tissue Donation Education for Critical Care Residents

Qualitative data corroborated that residents need more exposure to clinical cases, especially regarding DCD donors. A standardized education curriculum would be beneficial for all residents within the ICU. Developing a better... read more

Hydrocortisone plus Fludrocortisone for Adults with Septic Shock

The use of steroids in critically ill patients continues to be controversial. Whilst there are signals for improved cardiovascular parameters, this did not translate to clear mortality benefits. The most recent of these trials... read more

Abnormal Environmental Light Exposure in the ICU Environment

Patients' environmental light exposure in the intensive care unit is consistently low and follows a diurnal pattern. No effect of nighttime light exposure was observed on melatonin secretion. Inadequate daytime light exposure... read more

Dutch Ambitions on eHealth

Dutch government is encouraging the healthcare sector to expand telehealth (eHealth) services. Dutch government wants eHealth to become more widely available and is encouraging the healthcare sector to develop it further.... read more

High Generic Drug Prices and Market Competition: A Retrospective Cohort Study

Market competition levels were associated with a change in generic drug prices. Such measurements may be helpful in identifying older prescription drugs at higher risk for price change in the future. From 1.08 billion prescription... read more

Positive End-expiratory Pressure and Mechanical Power

Less than 7 cm H2O positive end-expiratory pressure reduced atelectrauma encountered at zero end-expiratory pressure. Above a defined power threshold, sustained positive end-expiratory pressure contributed to potentially... read more

The Gender Gap in Critical Care Medicine: How Are We Doing Globally?

Female enrollment into medical schools is increasing worldwide, but gender disparities persist in certain specialties, especially in critical care medicine. Published data on the scale of this issue is scarce and a recent... read more

CT-based Measurements Beat Framingham Risk Score in Predicting Future CVD Events

Assessment of abdominal aortic calcification using computed tomography (CT) is a highly effective predictor of future heart attack and CVD risk, according to research published in Radiology Oct. 2—more effective even than... read more

Magnesium Sulfate for Rapid Atrial Fibrillation?

Currently, several medications are recommended for the management of atrial fibrillation with rapid ventricular response in the emergency department including calcium channel blockers, beta blockers and digoxin (the optimal... read more

Update on Perioperative Acute Kidney Injury

Acute kidney injury (AKI) in the perioperative period is a common complication and is associated with increased morbidity and mortality. A standard definition and staging system for AKI has been developed, incorporating a... read more