ARDS and Prone Positioning

Prone positioning has been a treatment option for acute respiratory distress syndrome in critically ill patients. Since the COVID-19 pandemic, awake prone positioning has been utilized as a treatment option for non-intubated... read more

Management of Refractory COPD

Chronic obstructive pulmonary disease (COPD) is a common condition with an estimated global prevalence of almost 12 percent in adults over age 30 years [1-3]. Prior to the onset of the COVID-19 (coronavirus disease 2019)... read more

Ventilator Management: A Pre-Hospital Perspective

Ventilator Management: A Pre-Hospital Perspective

The goal of this book is to provide the most up to date information on mechanical ventilation based on current research, evidence based practice and my experiences as a flight paramedic and educator. A comprehensive look... read more

How I Perform Diaphragmatic Ultrasound in the ICU

The diaphragm is a thin, dome-shaped muscle, comprising a costal and crural part, and a non-contracting central tendon. Muscle fiber activation shortens and thickens the diaphragm in the zone of apposition, moving the dome... read more

Hemodynamic Monitoring Using Echocardiography in the Critically Ill

Hemodynamic Monitoring Using Echocardiography in the Critically Ill

The hemodynamic evaluation of patients with acute circulatory failure and respiratory failure has in the past usually been performed using invasive procedures but in recent years less invasive monitoring devices have been... read more

The Paracetamol Challenge in ICU

Paracetamol is one of the most widely prescribed medications in critically ill patients. Our intensive care unit (ICU) administered 50.133 g of paracetamol in 2023 (16.230 intravenous [IV] doses, 33.825 oral doses and 78... read more

Spontaneous Breathing Trials Should Be Adapted for Each Patient According To The Critical Illness

Unassisted SBTs, namely PSV0PEEP0 and T-piece trial, are the most appropriate to replicate the postextubation effort to breathe. In this multicentre randomized cross-over study, adult intensive care unit patients under... read more

Managing Blood Glucose Control in the ICU

Current evidence supports avoiding iatrogenic factors that aggravate hyperglycemia, such as early-PN and liberal corticosteroid use, and does not support TGC, except with accurate tools and protocols that prevent iatrogenic... read more

Invasive Fungal Infections in Non-neutropenic Patients

Critically ill patients, particularly those with features of immunosuppression, are susceptible to invasive fungal infections (IFI), which pose significant diagnostic and therapeutic challenges. Candida and Aspergillus,... read more

Pulmonary Hypertension: Controversial and Emerging Topics

Pulmonary Hypertension: Controversial and Emerging Topics

This book is a clinical guide to controversial and emerging topics in pulmonary hypertension. There are multiple challenges and unanswered questions encountered by clinicians that evaluate, diagnose and treat patients with... read more

Microbial Dynamics and Pulmonary Immune Responses in COVID-19 Secondary Bacterial Pneumonia

Secondary bacterial pneumonia (2°BP) is associated with significant morbidity following respiratory viral infection, yet remains incompletely understood. In a prospective cohort of 112 critically ill adults intubated... read more

Comprehensive Tracheostomy Care: The National Tracheostomy Safety Project Manual (Advanced Life Support Group)

Comprehensive Tracheostomy Care: The National Tracheostomy Safety Project Manual (Advanced Life Support Group)

Comprehensive Tracheostomy Care is a resource developed by the UK National Tracheostomy Safety Project (NTSP) to help promote and facilitate the safe management of tracheostomies and laryngectomies. The scope includes... read more

Outcomes and inflammation changes in different types of immunocompromised patients with critically ill COVID-19 admitted to ICU

Critically ill COVID-19 patients admitted to the ICU exhibit distinct clinical outcomes based on their immunosuppression status, with cancer patients facing the highest mortality rate due to variations in inflammatory responses... read more

Pulmonary Barotrauma in COVID-19 Patients: Experience From a Tertiary University Hospital

Mechanical ventilation (MV) in COVID-19 patients is often complicated with pulmonary barotrauma. The aim of this study was to determine the incidence and risk factors associated with the development of pulmonary barotrauma... read more

Delirium and Weakness Acquired in the ICU: Individual and Combined Effects on 90-Day Mortality in Survivors of Critical Illness

Mortality is substantially high among critically ill survivors who experience both delirium and weakness, although no additive effect on mortality was observed when these conditions occur together. Our findings highlight... read more

COVID-19 Leaves Lasting Impact on Nursing Practices and Job Satisfaction

The COVID-19 pandemic exacerbated the difficulties nurses experience, especially in emergency departments, requiring adjustments in practice care settings and continuing to impact their overall job satisfaction. Nursing... read more

Tracheostomies The Complete Guide

Tracheostomies The Complete Guide

Tracheostomies: The Complete Guide (2nd ed.) serves as a comprehensive resource for healthcare practitioners and patients navigating the complexities of tracheostomy and laryngectomy care. This edition emphasizes the... read more