Analgosedation and Delirium Practices in Critically Ill Patients
Before the COVID-19 pandemic, the management of analgosedation was characterized by the predominant use of targeted protocols that favored priority on mild and dynamic sedation in critically ill patients. During the pandemic... read more
Enhanced Prediction of ICU LOS Using a Stack Ensemble of Machine Learning Models
The Length of Stay (LoS) refers to the time between a patient's hospital admission and discharge. LoS is considered to increase as the complexity of the disease increases. A prolonged stay in the Intensive Care Unit (ICU)... read more
Hepatic Critical Care
This book focuses on the critical care of the patient with acute, acute on chronic and chronic liver failure as well as the peri-operative care of the patient with liver transplantation. Each of these disease processes is... read more
Risk Factors for Subsequent LRTI Following an Infant RSV Hospitalization
Fifteen percent of infants experience at least one other medically attended lower respiratory tract infection (MA LRTI) after an respiratory syncytial virus (RSV) hospitalization in the same season, and approximately half... read more
Predicting Sudden Decrease in Oxygenation in Mechanically Ventilated ICU Patients as a Surrogate Marker for ARDS
Acute Respiratory Distress Syndrome (ARDS) is a life-threatening form of respiratory failure characterized by widespread lung inflammation that severely impairs oxygenation. Affecting millions of patients worldwide, ARDS... read more
Unlocking the Predictive Power of Nutritional Scores in Septic Patients
The study highlights the mNUTRIC score's practicality and reliability in assessing nutritional and inflammatory risks in septic patients, particularly in non-ICU settings. These findings suggest its potential utility... read more
Designing, Implementing, and Enhancing a Rapid Response System
Written by leaders in the field, Designing, Implementing, and Enhancing a Rapid Response System, contains the tools needed to plan, develop, enhance, and customize a rapid response system (RRS) in your hospital. This... read more
Enteric Gram-negative Infections on Lung Transplant Clinical Outcomes
Lung transplant recipients (LTR) with more complicated post-operative courses were more likely to develop enteric gram-negative (GNR) infections which led to increased post-transplant morbidities. Pre-transplant GNR colonization... read more
Cumulative Fluid Balance During the First Three ICU Days in Septic Patients with Heart Failure
In septic patients with HFpEF, positive fluid balance of CFB-day1 might improve the prognosis of patients. However, from the second day, fluid overload was associated with poor prognosis. Therefore, we propose that on... read more
AKI and Mortality Predictors of Systemic Autoimmune Diseases and COVID-19
The present study highlights renal parameters and outcomes associated with various systemic autoimmune diseases and COVID-19. Patients who presented with low oxygen saturation (... read more
Prescribing Patterns and Effectiveness of Ceftolozane/Tazobactam in Immunosuppressed Patients
Treatment with Ceftolozane/Tazobactam (C/T) resulted in a high rate of clinical success in this real-world cohort of immunosuppressed patients, despite dosing that frequently deviated from labelled dosing. Pseudomonas... read more
Irwin and Rippe’s Intensive Care Medicine
With a focus on evidence-based, state-of-the-art information throughout, the eighth edition of Irwin and Rippe's Intensive Care Medicine offers authoritative guidance to the wide variety of specialty physicians and non-physicians... read more
Multi-dimensional Outcomes Following ECPR
Recent trials suggested that extracorporeal cardio-pulmonary resuscitation (ECPR) with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) or "ECMELLA" (VA-ECMO plus Impella) may improve short-term survival and neurological... read more
VEGFR1 Genetic Regulation During Sepsis and Association with ARDS Susceptibility
We identified biologically relevant protein quantitative trait loci (pQTLs) of vascular endothelial growth factor receptor 1 (VEGFR1) levels during sepsis in TCF20 and identified CYP2D6 as the gene more biologically implicated.... read more
Therapeutic Hypothermia After Cardiac Arrest
Therapeutic hypothermia has emerged as a very important treatment option for patients with cardiac arrest as it provides significant protection from developing neurologic injury once the patient has been successfully resuscitated.... read more
Bundling Procedures in Critically Ill Trauma Patients and ICU LOS
Intubated trauma patients who presented with certain mechanisms (gunshot wounds (GSW), pedestrian struck), received blood transfusions, or exhibited severe/profound ISS may be more likely to receive immediate bundled lines... read more
APRV vs. BIPAP Ventilation in COVID-19 Associated ARDS
Despite of higher mean tidal volumes and higher mean airway pressures in airway pressure release ventilation (APRV) vs. biphasic positive airway pressure (BIPAP), both modes did not present an increased risk of volu- or barotrauma... read more
Cytokeratin-18 Levels in COVID-19 Patients
This study analyzed 176 samples, including 63 ICU-admitted patients and 88 non-ICU-admitted patients. A substantial difference was found between the AST and CK-18 levels of the patients receiving ICU care and those who did... read more
Essentials of Neurosurgical Anesthesia & Critical Care
This handbook is aimed at first-line health care providers involved in the perioperative care of adult and pediatric neurosurgical patients. It is unique in its systematic focus on how to deal with common and important... read more
Favorable Outcomes When Using Prolonged CPR Combined with ECPR
Extracorporeal CPR (ECPR) combined with continuous renal replacement therapy (CRRT) successfully rescues a patient who experienced sudden cardiac arrest for 152 minutes. ECPR is an effective and advanced form of extracorporeal... read more
Emergency ECMO Deployment During Liver Transplantation in POPH Patients
Portopulmonary hypertension (POPH) is a challenge in the perioperative setting. Orthotopic liver transplantation (OLT) is a therapeutic option in that setting. ECMO may be necessary for patients with POPH in the perioperative... read more
Primary Management of Polytrauma
This well-illustrated book describes a practical approach to the primary management of patients who have multiple injuries, or polytrauma, with the aim of providing medical and paramedical personnel with the knowledge required... read more








