The PICU Handbook
The PICU Handbook is a unique, portable compilation of the information essential for residents and fellows to successfully navigate the modern Level 1 and Level 2 pediatric intensive care unit (PICU). Enhanced by numerous... read more
Exploring the Effectiveness of HFNC in the Neurointensive Care Unit
The high flow nasal cannula (HFNC) is becoming increasingly prevalent in both adult and pediatric general intensive care. Despite limited reporting in neurocritical care, we have successfully utilized HFNC in our cohort... read more
Antibiotic Prophylaxis Effectiveness in Polytrauma Patients
The results indicate that antibiotic prophylaxis has no significant effect on mortality and clinical status compared with placebo or standard care in adult polytrauma patients but may reduce the risk of VAP. However,... read more
Vital Signs and Serum Biomarkers Model Outperforms Shock Index in HCI Prediction
In this study of surgical ICU patients with concern for ongoing bleeding, a prediction model using serial VS and biomarkers outperformed the SI and may help identify those requiring hemorrhage control interventions (HCI). This... read more
Textbook of Neonatal Resuscitation
Powerful resource for interactive, simulation-based teaching and learning! The Neonatal Resuscitation Program (NRP) is an educational program jointly sponsored by the American Academy of Pediatrics (AAP) and the American... read more
Early Experience on Universal Prophylaxis in Infants Against RSV
During the 2023-2024 season, nirsevimab significantly reduced the risk of bronchiolitis and confirmed RSV infections in primary care, hospital, and pediatric ICU admissions among infants aged 0 to 11 months, even in a season... read more
Cytomegalovirus Infection in Immunocompromised ICU Patients: What Intensivists Need To Know
Cytomegalovirus (CMV) infection and disease in critically ill immunocompromised patients pose a unique challenge for intensivists. The broad spectrum of clinical presentations and the difficulty in distinguishing CMV-related... read more
Unlocking the Predictive Power of Nutritional Scores in Septic Patients
This study highlights the significant prognostic utility of nutritional status evaluation in septic patients admitted to internal medicine wards. Among the tools evaluated, the mNUTRIC score—likely because of its dual... read more
Dynamic Nomogram for AKI Prediction in ICU Patients with AHF
After strict screening, 1338 patients with acute heart failure (AHF) were included in the derivation set, and 3,129 in the validation set. Sepsis, use of human albumin, age, mechanical ventilation, aminoglycoside administration,... read more
Resource Utilization Associated with ECMO vs. Microaxial Flow Pump for Infarct-related Cardiogenic Shock
Microaxial flow pump was associated with lower resource utilization compared to venoarterial extracorporeal membrane oxygenation (VA-ECMO). Resource utilization should be incorporated in prospective RCTs and taken into account... read more
Risk Factors for Impairments in Quality of Life and Activities of Daily Living in Survivors of Critical Illness
This systematic review was able to identify that survivor of critical illnesses experienced changes in worsening quality of life, with impairment also in their functionality in terms of basic and instrumental activities of... read more
Central vs. Peripheral VA-ECMO Cannulation on Postoperative Graft Dysfunction in Lung Transplantation
Lung transplantation (LTx) is the definitive treatment for end-stage pulmonary diseases, with venoarterial extracorporeal membrane oxygenation (VA-ECMO) used as a common perioperative support. However, it remains unclear... read more
The Only EKG Book You’ll Ever Need
Clear and concise, The Only EKG Book You'll Ever Need has provided quick and accurate discussions on using an EKG to diagnose cardiac and non-cardiac conditions for nearly 30 years. This ninth edition is packed with full-color... read more
Unfractionated Heparin May Improve Near-term Survival in ICU Patients with Sepsis Pneumonia
This study found that early administration of heparin, particularly in sufficient doses (Heparin Sodium 5000 units/mL, 1 mL per dose, three times daily (TID)) for more than 7 d, was associated with reduced near-term mortality... read more
Management of Patients Supported with VA-ECMO
Veno-arterial extracorporeal membrane oxygenation (VA ECMO) application in adult patients has significantly increased in recent years. The Extracorporeal Life Support Organization (ELSO) registry includes more than 39,000... read more
Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences
Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices... read more
Predicting MODS in Trauma-induced Sepsis with Machine Learning Models
The nomogram and machine learning models provide enhanced predictive accuracy for multiple organ dysfunction syndrome (MODS) in trauma-induced sepsis patients compared to traditional scoring systems. These tools, accessible... read more
Postoperative Liver Dysfunction After Lung Transplantation with Extracorporeal Life Support and 1-year Mortality
In this retrospective cohort study, we identified an elevated 1-year mortality rate among patients who developed postoperative liver dysfunction, as defined by the presence of HLD, DILI-like symptoms, and cholestasis subsequent... read more
Mental Health in the First Year After ICU-treated Sepsis
Existing data on the prevalence of mental health impairments (MHI) following sepsis and intensive care are based predominantly on self-reported symptoms assessed by using questionnaires, small sample sizes, and clinically... read more
Extracorporeal Life Support: The ELSO Red Book, 6th Edition
Written by over two hundred experts from around the world, this new edition is the definitive reference text on Extracorporeal Life Support, providing both the latest evidence and practical advice on how to clinically manage... read more
Association Between the Lactate-to-Albumin Ratio (LAR) Index and AKI Risk in Critically Ill Patients with Sepsis
Lactate-to-albumin ratio (LAR) is an emergency predictive indicator of sepsis-related mortality. An elevated LAR is associated with poor outcomes in critically ill patients. However, its predictive value for acute kidney... read more
Which Antimicrobial Treatment for Patients with Bloodstream Infection During ECMO Support?
Enterococcus sp. was incriminated in about a third of BSI among patients with ECMO support. High appropriateness would only be obtained with piperacilline/tazobactam or carbapenems in association with vancomycin while 3rd... read more
