AKI and Mortality Predictors of Systemic Autoimmune Diseases and COVID-19
The present study highlights renal parameters and outcomes associated with various systemic autoimmune diseases and COVID-19. Patients who presented with low oxygen saturation (... read more
Prescribing Patterns and Effectiveness of Ceftolozane/Tazobactam in Immunosuppressed Patients
Treatment with Ceftolozane/Tazobactam (C/T) resulted in a high rate of clinical success in this real-world cohort of immunosuppressed patients, despite dosing that frequently deviated from labelled dosing. Pseudomonas... read more
Irwin and Rippe’s Intensive Care Medicine
With a focus on evidence-based, state-of-the-art information throughout, the eighth edition of Irwin and Rippe's Intensive Care Medicine offers authoritative guidance to the wide variety of specialty physicians and non-physicians... read more
Multi-dimensional Outcomes Following ECPR
Recent trials suggested that extracorporeal cardio-pulmonary resuscitation (ECPR) with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) or "ECMELLA" (VA-ECMO plus Impella) may improve short-term survival and neurological... read more
VEGFR1 Genetic Regulation During Sepsis and Association with ARDS Susceptibility
We identified biologically relevant protein quantitative trait loci (pQTLs) of vascular endothelial growth factor receptor 1 (VEGFR1) levels during sepsis in TCF20 and identified CYP2D6 as the gene more biologically implicated.... read more
Therapeutic Hypothermia After Cardiac Arrest
Therapeutic hypothermia has emerged as a very important treatment option for patients with cardiac arrest as it provides significant protection from developing neurologic injury once the patient has been successfully resuscitated.... read more
Bundling Procedures in Critically Ill Trauma Patients and ICU LOS
Intubated trauma patients who presented with certain mechanisms (gunshot wounds (GSW), pedestrian struck), received blood transfusions, or exhibited severe/profound ISS may be more likely to receive immediate bundled lines... read more
APRV vs. BIPAP Ventilation in COVID-19 Associated ARDS
Despite of higher mean tidal volumes and higher mean airway pressures in airway pressure release ventilation (APRV) vs. biphasic positive airway pressure (BIPAP), both modes did not present an increased risk of volu- or barotrauma... read more
Cytokeratin-18 Levels in COVID-19 Patients
This study analyzed 176 samples, including 63 ICU-admitted patients and 88 non-ICU-admitted patients. A substantial difference was found between the AST and CK-18 levels of the patients receiving ICU care and those who did... read more
Essentials of Neurosurgical Anesthesia & Critical Care
This handbook is aimed at first-line health care providers involved in the perioperative care of adult and pediatric neurosurgical patients. It is unique in its systematic focus on how to deal with common and important... read more
Favorable Outcomes When Using Prolonged CPR Combined with ECPR
Extracorporeal CPR (ECPR) combined with continuous renal replacement therapy (CRRT) successfully rescues a patient who experienced sudden cardiac arrest for 152 minutes. ECPR is an effective and advanced form of extracorporeal... read more
Emergency ECMO Deployment During Liver Transplantation in POPH Patients
Portopulmonary hypertension (POPH) is a challenge in the perioperative setting. Orthotopic liver transplantation (OLT) is a therapeutic option in that setting. ECMO may be necessary for patients with POPH in the perioperative... read more
Primary Management of Polytrauma
This well-illustrated book describes a practical approach to the primary management of patients who have multiple injuries, or polytrauma, with the aim of providing medical and paramedical personnel with the knowledge required... read more
Ventilator Associated Pneumonia in ICU: Identification, Evaluation and Prevention
This study highlights the significant prevalence of Pseudomonas aeruginosa (PA) as a major bacterial pathogen causing ventilator-associated pneumonia (VAP) in ICU patients, with a high detection rate of 71.7% in tested patients,... read more
Early Weaning From Invasive Mechanical Ventilation via HFNO vs. Conventional Weaning in ARF Patients
In patients with resolving acute hypoxemic respiratory failure (ARF), early extubation with high flow nasal oxygen is feasible and provides a better alternative to conventional weaning from invasive mechanical ventilation,... read more
New Insights: Mortality in Nosocomial Lower Respiratory Tract Infections
This multicenter, multinational study conducted in Europe and Latin America sheds light on the clinical landscape of nLRTI, which continues to be an essential issue in the context of critical care. We provide insights... read more
ICU-AW in Cardiogenic Shock Patients Requiring Mechanical Circulatory Support
This study provides insights into the characteristics of intensive care unit-acquired weakness (ICU-AW) in patients with Cardiogenic Shock (CS) requiring mechanical circulatory support (MCS). ICU-AW frequently occurred... read more
Rapid and Accurate Sepsis Identification Using AI
This study demonstrates that by providing streamlined predictions using CBC+DIFF data without requiring extensive clinical parameters, the AI-CDSS can be seamlessly integrated into clinical workflows, enhancing rapid, accurate... read more
New Insights: Inhaled Nitric Oxide in Severe COVID-19 Patients
This study provides novel insights into the use of inhaled nitric oxide in severe ARDS COVID-19 patients. Specifically, we demonstrate that the iNO effect of oxygenation improvement is delayed with a prolonged feature that... read more
CAR-T Therapy – Critical Care Considerations of Chimeric Antigen Receptor
Despite significantly improving the treatment of blood cancers, CAR T-cell therapy still faces significant hurdles due to its complex and varied toxicities, which require ongoing research to optimize management; while understanding... read more
Managing Recurrent Septic Shock – Dual Blood Purification with CytoSorb and oXiris
This case report presents a patient with recurrent septic shock who experienced significant clinical improvement after receiving adjunctive treatment with a combination of continuous renal replacement therapy (CRRT) using... read more
Cellular Therapy with Mesenchymal Stromal Cells in Sepsis
Cellular therapy with mesenchymal stromal cells (MSCs) is a promising therapeutic modality in sepsis. Positive effects are mainly associated with frequent infusions and the dose of 1 × 106 cell/kg. Larger scale studies... read more
