Evaluation Effects of Nebulized Hypertonic Saline and Nebulized Corticosteroids in Patients with ARDS
Acute respiratory distress syndrome (ARDS) is a common clinical syndrome of acute respiratory failure as a result of diffuse lung inflammation and oedema manifested by hypoxemia and stiffness in the lungs. This study... read more
Strong Ion Difference to Predict Mortality in Septic Shock: Mortality Prediction Model for Admission and 24-hour Mortality
Stewart's model examines the relationship between the movement of ions across biological membranes and the consequent changes in pH related to modifications in three dependent variables which are the strong ion difference... read more
72‐h Infusion of Prostacyclin in Mechanically Ventilated Patients with Pulmonary Infection and Endotheliopathy
Acute respiratory failure (ARF) is common in critically ill patients, and 50% of patients in intensive care units require mechanical ventilation. The COVID‐19 pandemic revealed that COVID‐19 infection induced ARF... read more
Increased Sound Levels in the Cardiac ICU Associated with Increased Heart Rate, Blood Pressure, and Sedation
Sound levels in the CICU were consistently higher than recommended. An increase in heart rate, blood pressure and sedation utilization may suggest a stress response to persistent and sudden loud sounds. Given known negative... read more
Multidisciplinary Collaborative Bundled Care Improves Outcomes in ICU Patients with Endotracheal Intubation
Multidisciplinary analgesic and sedative bundled care has demonstrated the potential to decrease restraint use in patients undergoing endotracheal intubation and mechanical ventilation, reduce the need for analgesic and sedative... read more
Corticosteroid Therapy and Pulmonary Embolism in Polytrauma Patients
Pulmonary embolism is a frequent complication in polytrauma patients. The aim of our study was to evaluate the effect of low-dose corticosteroid therapy on the incidence of pulmonary embolism (PE) in polytrauma patients.... read more
Succinate-containing Crystalloid Solution in Correction of COVID-19-associated Endotheliopathy
The use of a succinate-containing infusion solution in patients with a new coronavirus infection promotes a more rapid and sustainable correction of COVID-19-associated endotheliopathy, which, in turn, is manifested by a... read more
Weaning Sedation in Pediatric Intensive Care
The use of sedation and analgesia to provide comfort, safety, and pain treatment are central principles in the care of critically ill children. Most critically ill children are at risk of experiencing pain and discomfort... read more
Ketamine May Reduce Opioid Requirements Following Cardiac Surgery
Ketamine may be a reasonable choice for postoperative cardiac surgery analgesia and may reduce the need for opioids on discharge, and possibly during admission. This study is a single center, retrospective, observational,... read more
Predictors of Functional Impairment in Severe COVID-19 Patients Two Months After Discharge
The Post-COVID-19 Functional Status (PCFS) scale is a validated tool for assessing functional impairment in COVID-19 patients. While this retrospective monocentric study identified multiple risk factors associated with... read more
Management of Pain, Anxiety, and Delirium in Critically Injured Pediatric Trauma Patients
PICU-specific care bundles have been beneficial in standardizing the assessment, prevention and treatment of pain, anxiety and delirium. While these practices show promise in addressing current management challenges in... read more
Shock Indices as Prognostic Indicators: among Sepsis and Septic Shock Patients with and without Comorbidities Presenting to Emergency Department
Almost 30 million people are affected, and 3 million deaths happen every year because of sepsis. According to WHO's (World Health Organization) Global Report on Epidemiology and Burden of Sepsis report 2020, half of the... read more
Early Antiviral Use and Supplemental Oxygen Decrease the Risk of Secondary Bacterial Infections
This nested case control study shows that early use of antiviral agents and non-invasive oxygen supplementation leads to decreased susceptibility to secondary bacterial infections. On the other hand, use of antibiotics... read more
Cardiac Damage in Patients Infected with Different COVID-19 Variants of Concern
Coronavirus Disease 2019 causes significant morbidity, and different variants of concern (VOCs) can impact organ systems differently. We conducted a single-center retrospective cohort analysis comparing biomarkers and... read more
Long-term Prevalence of PTSD Symptom in Family Members of Severe COVID-19 Patients
The prevalence of PTSD-related symptoms among family members of severely ill COVID-19 patients stayed high up to 18 months after the patients' ICU discharge. Some showed delayed onset of PTSD-related symptoms in the remote... read more
Two Biomarkers Improve CRB-65 Predictability for Death Due to Community-Acquired Pneumonia
Augmenting CRB-65 (confusion, respiratory rate, blood pressure, and age 65 or older) score with troponin T high-sensitive (TnT-hs) and procalcitonin (PCT) help to predict death or intensive care unit (ICU) admission of patients... read more
In COVID-19 Patients Supported with ECMO, ICU Mortality Is Associated with the Blood Transfusion Rate
Three-quarters of patients 3 days in these centers between July 2020 and November 2021 were included in the analysis.... read more
Predicting ICU Admission in COVID-19-Infected Pregnant Women Using Machine Learning
Routinely collected clinical and laboratory data of COVID-19-infected pregnant women may help recognize high-risk groups who are more liable for complications and more severe course or prognosis and require an ICU admission.... read more
Mini Bronchoalveolar Lavage vs. Endo-Tracheal Aspirate in Diagnosing Bacterial Pneumonia in ICU
This study supports the use of endotracheal aspirate (ETA) as a cost-effective and efficient alternative to mBAL for the diagnosis of pneumonia in intubated ICU patients, particularly in settings where resources are limited.... read more
Temporary ICU – Preparedness Concept to Increase Capacity
The temporary ICU (TICU) concept demonstrates promising potential in enhancing preparedness and maintaining critical care surge capacity during pandemics or mass casualty incidents. While shortages of medical equipment,... read more
Therapy Dogs Aren’t Just for Patients
My hospital brought in a therapy dog for our ED team after a critical incident stress debriefing (CISD). I had never received dog therapy before. The big eyes and loving licks on our hands honestly helped. Perhaps what... read more
The predictive value of LAR for determining the need for ICU admission among hospitalized patients with community-acquired pneumonia
In this study, lactate-to-albumin ratio (LAR) was found to be a good predictor of ICU admissions in hospitalized patients with CAP and was non-inferior to PSI or CURB-65 scores. LAR was found to be a good predictor of... read more
