Lactated Ringer’s a Clear Winner for Pancreatitis Resuscitation
Pancreatitis, a common and challenging condition, presents frequently in emergency departments across the country, affecting around 34 of every 100,000 adults annually. This often-severe disease is marked by inflammation... read more
Misunderstanding Buffering in Critical Illness
It is was disappointing to read the recent review in Intensive Care Medicine on buffering in metabolic acidosis. I consider this a "pre-Copernican" approach to acid–base that does not respect basic physical–chemical principles. The... read more
Prediction of Prolonged Mechanical Ventilation in the ICU via Machine Learning
Early recognition of risk factors for prolonged mechanical ventilation (PMV) could allow for early clinical interventions, prevention of secondary complications such as nosocomial infections, and effective triage of hospital... read more
Heart Rate Control in Septic Shock: Echocardiographic Evaluation and Monitoring
Our study demonstrated a modest reduction in heart rate by approximately 10 beats per minute, accompanied by a slower decrease in noradrenaline requirements com-pared to the control group in the overall population. This... read more
Optimizing ICU Weaning: Globalizing Personalized Weaning Strategies
this study provides compelling evidence supporting the concept of individualized weaning in the ICU. By tailoring spontaneous breathing trial (SBT) methods to match specific patient conditions, it represents an essential... read more
Amazon Outlet – Deal Hunter’s Paradise Awaits
Ready to uncover incredible savings? Dive into the Amazon Outlet and explore our massive selection of Overstock Deals. Forget waiting for a sales event, we offer genuinely low prices on markdowns and overstocks all year round.... read more
Effect on Norepinephrine Administration Timing on Prognosis of Septic Shock Patients
Norepinephrine initiation ≤1 h is associated with lower 28-day mortality in patients with septic shock. Early norepinephrine administration is also associated with a shorter time to achieve MAP ≥65 mmHg, lower 24-h intravenous... read more
Sepsis: Clinical Diagnosis and Treatment
Sometimes our body's reaction to infection can result in damage to internal tissues and organs. Such a condition is referred to as sepsis. Some of the symptoms of sepsis are high fever, increased heart and breathing rate,... read more
An Optimal Antibiotic Selection Framework for Sepsis Patients Using AI
In this work we present OptAB, the first completely data-driven online-updateable antibiotic selection model based on Artificial Intelligence (AI) for Sepsis patients accounting for side-effects. OptAB performs an iterative... read more
Personalized Therapies in ARDS
Acute respiratory distress syndrome (ARDS) can result from a variety of clinical conditions, causing lung injury either directly through local inflammation or indirectly because of systemic inflammatory mediators ARDS is... read more
Personalizing Beta-blockade in Septic Shock
Clinical trials provide only part of the necessary framework for clinical decision-making. In practice, a detailed understanding of each patient’s hemodynamic profile is essential. We believe that the echocardiography-guided... read more
Metabolic Disorders and Critically Ill Patients: From Pathophysiology to Treatment
Cellular metabolic abnormalities are responsible for systems and organ failures, so the modern approach of organ dysfunctions now includes prevention or treatment of such disorders. This book is a comprehensive tool, allowing... read more
Lymphocyte Count Trajectories Associated with Prognosis of Sepsis Patients
Three distinct lymphocyte trajectories were identified in sepsis patients using GBTM. Trajectory 3 was a strong predictor of 7-day and 28-day mortality, while Trajectory 1 was associated with early death. These findings... read more
Mechanical Ventilation Timing in Sepsis
A recent study by Dr. Kim and colleagues examined the association between the timing of mechanical ventilation (MV) and clinical outcomes in ICU patients with sepsis. The study included 2440 adult sepsis patients from... read more
AI Interpretation of Chest Radiographs in the ICU. Ready for Prime Time?
Chest radiography (CXR) is the primary tool to visualize thoracic pathologies in the ICU. However, accurate interpretation of CXRs is challenging, even when imaging is performed under optimal conditions. This results... read more
The Infectious Disease Diagnosis: A Case Approach
This text uses cases to illustrate differential diagnoses of various infectious diseases. Unlike any other book on the market, this book is specifically designed for ease of use and can cater to a variety of medical professionals... read more
Outcomes of Older Adults With Sepsis at Admission to an ICU
Our study suggests that treating older adults with therapies recommended by the Surviving Sepsis Campaign may improve outcomes in this age group, although mortality remains high for older adults with sepsis. In addition,... read more
Rethinking Energy and Protein Provision for Critically Ill Patients
In critically ill patients, we suggest that energy and protein be delivered progressively in stable or recovering patients. If a patient deteriorates, regardless of days spent in the ICU, low-dose energy and protein should... read more
The Beta-Blocker Story: Getting It Right
The idea of using beta-blockers as a treatment for ventricular fibrillation occurred to James Black over 60 years ago. He developed propranolol and cimetidine, among other pharmacologic agents, work for which he won the Nobel... read more
Early Tracheostomy in Ventilated COVID-19 Patients Reduces VAP Incidence
Tracheostomy can reduce mechanical ventilation (MV) duration, ICU and hospital length of stay (LOS), and ventilator-associated pneumonia (VAP) risk in critically ill patients. The timing of tracheostomy in COVID-19 patients... read more
ARF Caused by Penicillium Marneffei Infection After Kidney Transplantation
Penicillium Marneffei (PM) infections often present with nonspecific clinical manifestations, and severe respiratory failure (ARF) after infection is particularly uncommon. This case report a patient who developed severe... read more
Intranasal Dexmedetomidine vs. Inhaled Nitrous Oxide for Pediatric Procedural Sedation and Analgesia
The results of this clinical trial support that IN DEX is not inferior to 50% nitrous oxide in providing analgesia for a painful procedure among children 3–15 years of age. Furthermore, IN DEX can be considered as an alternative... read more
