Reducing Natalizumab Concentration May Reduce PML Risk
Serum concentrations of natalizumab do not appear to rise before patients with relapsing-remitting multiple sclerosis are diagnosed with progressive multifocal leukoencephalopathy, contradicting the hypothesis that exposure... read more
Cooling patients with TBI improve survival chances
New research from Royal Holloway published today in Critical Care Medicine shows that lowering the body temperature of people who have suffered a traumatic brain injury (TBI) as soon as possible after the trauma may significantly... read more
Effectiveness of Pre-Hospital Blood Products
University of Warwick is collaborating with researchers at the NIHR Surgical Reconstruction and Microbiology Research Centre (SRMRC) to support a ground-breaking new study to investigate the effectiveness of giving patients... read more
Milestone-based Assessment for Internal Medicine Residents
This Cross-Sectional study investigates how well correlated are 2 academic rating systems measuring medicine residents' training and whether medical knowledge scores correlate with American Board of Internal Medicine... read more
Redirecting Videolaryngoscopy
The debate of VL versus DL is not a new one and most will remember several years ago when respected voices were making strong statements about the impending irrelevance of DL as they hailed a new standard intubation device,... read more
Statins Associated with Reduced Alzheimer Risk
An analysis of Medicare data suggests that high use of cholesterol-lowering statins was associated with a reduced risk of Alzheimer’s disease (AD), according to an article published online in JAMA Neurology. Previous research... read more
Uncontrolled Bleeding Stopped By Injectable Viscous Hydrogel
A new study describes a novel embolic agent for endovascular embolization procedures that has a hemostatic activity comparable to that of metallic coils, the current gold standard. The nanocomposite STBs are injected through... read more
Kiosk for Patient Self Check-In Launched by drchrono
Mobile EHR provider drchrono has unveiled a new Kiosk that equips provider offices for patient self check-in and new Patient Education functionality on iPad enabling providers to share their materials with patients. With... read more
Plazomicin Succeeds in Phase 3 cUTI and CRE Trial
Plazomicin an antibiotic being developed to fight multidrug-resistant bacterial infections, has met the primary objective of noninferiority compared with meropenem in a phase 3 registration trial among patients with complicated... read more
Severe Adult ARDS Prediction Models
Outcomes and survival prediction models for severe adult acute respiratory distress syndrome treated with extracorporeal membrane oxygenation. Although the use of ECMO for severe refractory ARDS has markedly increased since... read more
Measuring Moral Distress Among Critical Care Clinicians
Moral distress is a common experience among critical care professionals, leading to frustration, withdrawal from patient care, and job abandonment. The Italian Moral Distress Scale-Revised is a valid and reliable instrument... read more
Glutamine, fish oil and antioxidants in critical illness
We hypothesize that the harmful effect of IMHP compared to HP enteral nutrition in a heterogeneous group of critically ill patients is limited to the medical critically ill patients and mediated by an early increase in (epa... read more
Anesthesiologist reaction time increased after night call
For anesthesiologists, reaction time increases after a night call, with greater increases seen in correlation with reliance on avoidance as a coping mechanism. Post-call psychomotor vigilance test mean reaction time decreased... read more
End-Inspiratory Pause Prolongation in ARDS Patients
Prolonging EIP allowed a significant decrease in Vt without changes in PaCO2 in passively ventilated ARDS patients. This produced a significant decrease in plateau pressure and driving pressure and significantly increased... read more
Blood Products Can Safely be Transported by Drones
Blood products don't seem to suffer damage when transported by drones, researchers report. Large bags of blood products, such as those transfused into patients everyday, can maintain temperature and cellular integrity... read more
Non-invasive Respiratory Support and Methylxanthines Reduce Re-Intubations
In a meta-analysis of randomized studies evaluating efforts to reduce re-intubations and respiratory failure in preterm infants, non-invasive respiratory support and use of methylxanthines (theophylline, caffeine) were found... read more
VR Technology for Surgical Procedures Planning
Researchers at the University of Basel in Switzerland developed a technology that uses CT data to generate 3-D images that can be viewed in a virtual environment to help surgeons as they plan surgical procedures. The technology,... read more
